Disputas- Master of Science Wei Meng

Avhandlingen er tilgjengelig her! The doctoral thesis! Prøveforelesning starter kl. 09.15 i auditorium Cortex, MH2. Prøveforelesningen over oppgitt emne: “Current and future molecular biomarkers for inflammatory bowel disease: opportunities and challenges for clinical implementation”. Prøveforelesningen strømmes her/ The trial lecture will be streamed here. Disputasen starter 11.15 i auditorium Cortex, MH2. Disputasen strømmes her/ The defense will be streamed here. Auditoriet er åpent for publikum. Disputasen vil strømmes og et opptak vil være tilgjengelig i et døgn. The auditorium is open to the public. The defense will still be streamed, and a recording of the disputation will be available for 24 hours.

Populærvitenskapelig sammendrag av avhandlingen:

Ulcerative colitis (UC) is a chronic inflammatory disease. The increasing incidence of UC worldwide is of global concern and is a burden to the healthcare system.
The exact cause of UC is unknown. Several factors including environment, genetics, and immune responses contribute to UC onset. As a chronic disease, UC cannot be cured and has both active and inactive states.
The treatment goal is to maintain UC patients in an inactive state (remission). Patients in remission relapse frequently and there are no existing methods for reliable prognosis of relapse.
Although studies have intensively focused on active UC, the state of remission is not well understood. The application of sequencing data together with bioinformatic analysis may provide a better understanding of UC in remission at a molecular level and might identify potential predictors for relapse. The results might improve patient outcomes and UC management.

Hovedveileder
Professor Ruth H. Paulssen, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.


Biveileder
Ph.d. Kay Martin Johnsen, Universitetssykehuset Nord Norge.
Senior forsker Christopher G. Fenton, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet. 

Bedømmelseskomité
Forsker Atle van Beelen Granlund, St. Olav's Hospital – 1. opponent.
Ph.d. Thomas Fleischer, Oslo universitetssykehus – 2. opponent.
Professor Eva Sjøttem, Institutt for medisinsk biologi, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet – leder av komité.

Disputasleder: førsteamanuensis Torgil Riise Vangberg, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.