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Aud Karin Øvervatn

Avdelingsingeniør Institutt for medisinsk biologi
Engelsk flaggikon Samisk flaggikon

Autofagi
Cellesignalering

  • Hoem, Gry; Larsen, Kenneth Bowitz; Øvervatn, Aud Karin; Brech, Andreas; Lamark, Trond; Sjøttem, Eva; Johansen, Terje. The FMRpolyGlycine protein mediates aggregate formation and toxicity independent of the CGG mRNA hairpin in a cellular model for FXTAS. Frontiers in Genetics 2019; Volum 10. ISSN 1664-8021.s doi: 10.3389/fgene.2019.00249.

  • Overå, Katrine Stange; Garcia Garcia, Juncal; Bhujabal, Zambarlal; Jain, Ashish; Øvervatn, Aud Karin; Larsen, Kenneth Bowitz; Deretic, Vojo; Johansen, Terje; Lamark, Trond; Sjøttem, Eva. TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1. Journal of Cell Science 2019; Volum 132:jcs236596 (23). ISSN 0021-9533.s 1 - 16.s doi: 10.1242/jcs.236596.

  • Bhujabal, Zambarlal; Birgisdottir, Åsa birna; Sjøttem, Eva; Brenne, Hanne Britt; Øvervatn, Aud Karin; Habisov, Sabrina; Kirkin, Vladimir; Lamark, Trond; Johansen, Terje. FKBP8 recruits LC3A to mediate Parkin-independent mitophagy. EMBO Reports 2017; Volum 18 (6). ISSN 1469-221X.s 947 - 961.s doi: 10.15252/embr.201643147.

  • Olsvik, Hallvard Lauritz; Lamark, Trond; Takagi, Kenji; Larsen, Kenneth Bowitz; Evjen, gry; Øvervatn, Aud Karin; Mizushima, Tsunehiro; Johansen, Terje. FYCO1 contains a C-terminally extended, LC3A/B-preferring LC3-interacting region (LIR) motif required for efficient maturation of autophagosomes during basal autophagy. Journal of Biological Chemistry 2015; Volum 290 (49). ISSN 0021-9258.s 29361 - 29374.s doi: 10.1074/jbc.M115.686915.

  • Alemu, Endalkachew Ashenafi; Lamark, Trond; Torgersen, Knut Martin; Birgisdottir, Åsa birna; Larsen, Kenneth Bowitz; Jain, Ashish; Olsvik, Hallvard Lauritz; Øvervatn, Aud Karin; Kirkin, Vladimir; Johansen, Terje. ATG8 Family Proteins Act as Scaffolds for Assembly of the ULK Complex SEQUENCE REQUIREMENTS FOR LC3-INTERACTING REGION (LIR) MOTIFS. Journal of Biological Chemistry 2012; Volum 287 (47). ISSN 0021-9258.s doi: 10.1074/jbc.M112.378109.

  • Pankiv, Serliy; Alemu, Endalkachew; Brech, Andreas; Bruun, Jack-Ansgar; Lamark, Trond; Øvervatn, Aud Karin; Bjørkøy, Geir; Johansen, Terje. FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport. Journal of Cell Biology 2010; Volum 188 (2). ISSN 0021-9525.s 253 - 269.s doi: 10.1083/jcb.200907015.

  • Jain, Ashish; Lamark, Trond; Sjøttem, Eva; Larsen, Kenneth Bowitz; Awuh, Jane Atesoh; Øvervatn, Aud Karin; McMahon, Michael; Hayes, John D; Johansen, Terje. p62/SQSTM1 Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription. Journal of Biological Chemistry 2010; Volum 285 (29). ISSN 0021-9258.s 22576 - 22591.s doi: 10.1074/jbc.M110.118976.

  • Larsen, Kenneth Bowitz; Lamark, Trond; Øvervatn, Aud Karin; Harneshaug, Ingvill; Johansen, Terje; Bjørkøy, Geir. A reporter cell system to monitor autophagy based on p62/SQSTM1. Autophagy 2010; Volum 6 (6). ISSN 1554-8627.s 784 - 793.

  • Clausen, Terje; Lamark, Trond; Isakson, Pauline; Finley, Kim; Larsen, Kenneth Bowitz; Brech, Andreas; Øvervatn, Aud Karin; Stenmark, Harald; Bjørkøy, Geir; Simonsen, Anne; Johansen, Terje. p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy. Autophagy 2010; Volum 6 (3). ISSN 1554-8627.s 330 - 344.s doi: 10.4161/auto.6.3.11226.

  • Pankiv, Serliy; Lamark, Trond; Bruun, Jack-Ansgar; Øvervatn, Aud Karin; Bjørkøy, Geir; Johansen, Terje. Nucleocytoplasmic Shuttling of p62/SQSTM1 and Its Role in Recruitment of Nuclear Polyubiquitinated Proteins to Promyelocytic Leukemia Bodies. Journal of Biological Chemistry 2010; Volum 285 (8). ISSN 0021-9258.s 5941 - 5953.s doi: 10.1074/jbc.M109.039925.

  • Kirkin, Vladimir; Lamark, Trond; Sou, Yu-Shin; Bjørkøy, Geir; Nunn, Jennifer Ann Lillebo; Bruun, Jack-Ansgar; Shvets, Elena; McEwan, David G.; Clausen, Terje; Wild, Philipp; Bilusic, Ivana; Theurillat, Jean-Philippe; Øvervatn, Aud Karin; Ishii, Tetsuro; Elazar, Zvulun; Komatsu, Masaaki; Dikic, Ivan; Johansen, Terje. A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates. Molecular Cell 2009; Volum 33 (4). ISSN 1097-2765.s 505 - 516.s doi: 10.1016/j.molcel.2009.01.020.

  • Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Øvervatn, Aud Karin; Brech, Andreas; Johansen, Terje. MONITORING AUTOPHAGIC DEGRADATION OF P62/SQSTM1. Methods in Enzymology 2009; Volum 452. ISSN 0076-6879.s 181 - 197.s doi: 10.1016/S0076-6879(08)03612-4.

  • Pankiv, Serliy; Clausen, Terje; Lamark, Trond; Brech, A; Bruun, Jack-Ansgar; Outzen, heidi; Øvervatn, Aud Karin; Bjørkøy, Geir; Johansen, Terje. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. (Fulltekst: http://www.jbc.org/cgi/content/full/282/33/24131 Journal of Biological Chemistry 2007; Volum 282. ISSN 0021-9258.s 24131 - 24145.s doi: 10.1074/jbc.M702824200.

  • Bjørkøy, Geir; Lamark, Trond; Brech, A; Outzen, heidi; Perander, maria; Øvervatn, Aud; Stenmark, H; Johansen, Terje. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. Journal of Cell Biology 2005; Volum 171. ISSN 0021-9525.s 603 - 614.

  • Bjørkøy, G; Lamark, T; Brech, Andreas; Outzen, H; Perander, M; Øvervatn, A; Stenmark, Harald Alfred; Johansen, T.. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. Journal of Cell Biology 2005; Volum 171. ISSN 0021-9525.s 603 - 614.

  • Lamark, Trond; Perander, maria; Outzen, Heidi; Kristiansen, kurt; Øvervatn, Aud Karin; Michaelsen, Espen; Bjørkøy, Geir; Johansen, Terje. Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.. (Fulltekst: http://www.jbc.org/cgi/pmidlookup?view=long&pmid=12813044 Journal of Biological Chemistry 2003; Volum 10 (278(36)). ISSN 0021-9258.s 34568 - 34581.s doi: 10.1074/jbc.M303221200.

  • Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Brech, A; Outzen, heidi; Perander, maria; Øvervatn, Aud; Stenmark, H; Johansen, Terje. P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3. Imaging Week 2006-11-13 - 2006-11-15 2006.

  • Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Brech, A; Outzen, heidi; Perander, maria; Øvervatn, Aud; Stenmark, H; Johansen, Terje. P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3. 4th International Symposium on Autophagy: Exploring the Froniers of Autophagy Research 2006-10-01 - 2006-10-05 2006.

  • Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Brech, A; Outzen, heidi; Øvervatn, Aud; Stenmark, H; Johansen, Terje. p62 as a direct link between protein aggregates and the autophgic machinery. Invited oral pesentation 2006-05-05 - 2006-05-05 2006.

  • Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Brech, A; Outzen, heidi; Perander, maria; Øvervatn, Aud; Stenmark, H; Johansen, Terje. P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3. Invited oral presentation 2006-11-16 - 2006-11-16 2006.

  • Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Brech, A; Outzen, heidi; Perander, maria; Øvervatn, Aud; Stenmark, H; Johansen, Terje. P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3. Imaging Week 2006-11-13 - 2006-11-15 2006.

  • Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Brech, A; Outzen, heidi; Perander, maria; Øvervatn, Aud; Stenmark, H; Johansen, Terje. P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3. 4th International Symposium on Autophagy: Exploring the Froniers of Autophagy Research 2006-10-01 - 2006-10-05 2006.

  • Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Brech, A; Outzen, heidi; Øvervatn, Aud; Stenmark, H; Johansen, Terje. p62 as a direct link between protein aggregates and the autophgic machinery. Invited oral pesentation 2006-05-05 - 2006-05-05 2006.

  • Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Brech, A; Outzen, heidi; Perander, maria; Øvervatn, Aud; Stenmark, H; Johansen, Terje. P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3. Invited oral presentation 2006-11-16 - 2006-11-16 2006.

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