Aud Karin Øvervatn
Overingeniør
Stillingsbeskrivelse
Autofagi
Cellesignalering
Gry Hoem,
Kenneth Bowitz Larsen,
Aud Karin Øvervatn,
Andreas Brech,
Trond Lamark,
Eva Sjøttem
m.fl.:
The FMRpolyGlycine protein mediates aggregate formation and toxicity independent of the CGG mRNA hairpin in a cellular model for FXTAS
Katrine Stange Overå,
Juncal Garcia Garcia,
Zambarlal Bhujabal,
Ashish Jain,
Aud Karin Øvervatn,
Kenneth Bowitz Larsen
m.fl.:
TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1
Zambarlal Bhujabal,
Åsa birna Birgisdottir,
Eva Sjøttem,
Hanne Britt Brenne,
Aud Karin Øvervatn,
Sabrina Habisov
m.fl.:
FKBP8 recruits LC3A to mediate Parkin-independent mitophagy
EMBO Reports 05. april 2017 DOI
Hallvard Lauritz Olsvik,
Trond Lamark,
Kenji Takagi,
Kenneth Bowitz Larsen,
gry Evjen,
Aud Karin Øvervatn
m.fl.:
FYCO1 contains a C-terminally extended, LC3A/B-preferring LC3-interacting region (LIR) motif required for efficient maturation of autophagosomes during basal autophagy
Endalkachew Ashenafi Alemu,
Trond Lamark,
Knut Martin Torgersen,
Åsa birna Birgisdottir,
Kenneth Bowitz Larsen,
Ashish Jain
m.fl.:
ATG8 Family Proteins Act as Scaffolds for Assembly of the ULK Complex SEQUENCE REQUIREMENTS FOR LC3-INTERACTING REGION (LIR) MOTIFS
Serliy Pankiv,
Endalkachew Alemu,
Andreas Brech,
Jack-Ansgar Bruun,
Trond Lamark,
Aud Karin Øvervatn
m.fl.:
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
Journal of Cell Biology 2010 DOI
Serliy Pankiv,
Trond Lamark,
Jack-Ansgar Bruun,
Aud Karin Øvervatn,
Geir Bjørkøy,
Terje Johansen
:
Nucleocytoplasmic Shuttling of p62/SQSTM1 and Its Role in Recruitment of Nuclear Polyubiquitinated Proteins to Promyelocytic Leukemia Bodies
Journal of Biological Chemistry 2010 DOI
Ashish Jain,
Trond Lamark,
Eva Sjøttem,
Kenneth Bowitz Larsen,
Jane Atesoh Awuh,
Aud Karin Øvervatn
m.fl.:
p62/SQSTM1 Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription
Journal of Biological Chemistry 2010 DOI
Kenneth Bowitz Larsen,
Trond Lamark,
Aud Karin Øvervatn,
Ingvill Harneshaug,
Terje Johansen,
Geir Bjørkøy
:
A reporter cell system to monitor autophagy based on p62/SQSTM1
Autophagy 2010
Terje Clausen,
Trond Lamark,
Pauline Isakson,
Kim Finley,
Kenneth Bowitz Larsen,
Andreas Brech
m.fl.:
p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
Autophagy 2010 DOI
Geir Bjørkøy,
Trond Lamark,
Serliy Pankiv,
Aud Karin Øvervatn,
Andreas Brech,
Terje Johansen
:
MONITORING AUTOPHAGIC DEGRADATION OF P62/SQSTM1
Methods in Enzymology 2009 DOI
Vladimir Kirkin,
Trond Lamark,
Yu-Shin Sou,
Geir Bjørkøy,
Jennifer Ann Lillebo Nunn,
Jack-Ansgar Bruun
m.fl.:
A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates
Molecular Cell 2009 DOI
Serliy Pankiv,
Terje Clausen,
Trond Lamark,
A Brech,
Jack-Ansgar Bruun,
heidi Outzen
m.fl.:
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
Geir Bjørkøy,
Trond Lamark,
A Brech,
heidi Outzen,
maria Perander,
Aud Øvervatn
m.fl.:
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
Journal of Cell Biology 2005
G Bjørkøy,
T Lamark,
Andreas Brech,
H Outzen,
M Perander,
A Øvervatn
m.fl.:
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
Journal of Cell Biology 2005
Trond Lamark,
maria Perander,
Heidi Outzen,
kurt Kristiansen,
Aud Karin Øvervatn,
Espen Michaelsen
m.fl.:
Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.
Geir Bjørkøy,
Trond Lamark,
Serliy Pankiv,
A Brech,
heidi Outzen,
maria Perander
m.fl.:
P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3
2006
Geir Bjørkøy,
Trond Lamark,
Serliy Pankiv,
A Brech,
heidi Outzen,
maria Perander
m.fl.:
P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3
2006
Geir Bjørkøy,
Trond Lamark,
Serliy Pankiv,
A Brech,
heidi Outzen,
Aud Øvervatn
m.fl.:
p62 as a direct link between protein aggregates and the autophgic machinery
2006
Geir Bjørkøy,
Trond Lamark,
Serliy Pankiv,
A Brech,
heidi Outzen,
maria Perander
m.fl.:
P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3
2006
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