Bilde av Hadler-Olsen, Elin Synnøve
Bilde av Hadler-Olsen, Elin Synnøve
Institutt for medisinsk biologi elin.hadler-olsen@uit.no +4777620912 48197033

Elin Synnøve Hadler-Olsen


Professor

Stillingsbeskrivelse

Professor oral anatomi og patologi

Jeg er utdannet tannlege og underviser om munn- og tenners oppbygning og funksjon normalt og i ulike sykdomstilstander. Forskningen min er også sentrert rundt munn og tenner der jeg blant annet jobber med problemstillinger rundt kreft i munnen og munn- og tannhelsedata fra befolkningsstudier.

 


  • Elin Synnøve Hadler-Olsen, Malin Hansen, Michelle Palo, Marta Warzoszczak :
    Alkohol som risikofaktor for hode-halskreft – en litteraturstudie
    Norsk tannlegeforening Tidende 2023 DOI
  • Hege Nermo, Elin Synnøve Hadler-Olsen :
    Are dental visiting patterns and oral pain associated with dental disease among Norwegian adults? A cross-sectional study based on the Tromsø study
    Clinical and Experimental Dental Research 2023 ARKIV / DOI
  • Farah Asa'ad, Natalia Petrenya, Birgitta Jönsson, Gro Eirin Holde, Nils Oscarson, Elin Synnøve Hadler-Olsen m.fl.:
    Polymorphism in epigenetic regulating genes in relation to periodontitis, number of teeth, and levels of high-sensitivity C-reactive protein and glycated hemoglobin: The Tromsø Study 2015-2016
    Journal of Periodontology 2023 ARKIV / DOI
  • Renate Harriet Andreassen, Birgitta Jönsson, Elin Synnøve Hadler-Olsen :
    Oral health related quality of life in long-term survivors of head and neck cancer compared to a general population from the seventh Tromsø study
    BMC Oral Health 2022 ARKIV / DOI
  • Juliane Winkler, Pengyuan Liu, Kiet Phong, Johanna H. Hinrichs, Nassim Ataii, Katherine Williams m.fl.:
    Bisphenol A replacement chemicals, BPF and BPS, induce protumorigenic changes in human mammary gland organoid morphology and proteome
    Proceedings of the National Academy of Sciences of the United States of America 2022 ARKIV / DOI
  • Renate Andreassen, Elin Synnøve Hadler-Olsen :
    Eating and speech problems in oral and pharyngeal cancer survivors – Associations with treatment-related side-effects and time since diagnosis
    Special Care in Dentistry: managing special patients, settings, and situations 2022 ARKIV / DOI
  • Sigurd Hadler-Olsen, Jeanett Steinnes, Hege Nermo, Anders Sjögren, Elin Synnøve Hadler-Olsen :
    Pain, discomfort, and functional impairment after extraction of primary teeth in children with palatally displaced canines–a randomized control trial comparing extraction of the primary canine versus extraction of the primary canine and the primary first molar
    Acta Odontologica Scandinavica 2022 ARKIV / DOI
  • Rabeia Almahmoudi, Abdelhakim Salem, Elin Synnøve Hadler-Olsen, Gunbjørg Svineng, Tuula Salo, Ahmed Al-Samadi :
    The effect of interleukin-17F on vasculogenic mimicry in oral tongue squamous cell carcinoma
    Cancer Science 2021 ARKIV / DOI
  • Elin Synnøve Hadler-Olsen, Birgitta Jönsson :
    Oral health and use of dental services in different stages of adulthood in Norway: a cross sectional study
    BMC Oral Health 2021 ARKIV / DOI
  • Elin Synnøve Hadler-Olsen, Elizabeth Thon, Gro Eirin Holde, Birgitta Jönsson, Nils Oscarson, Anders Tillberg :
    Temporomandibular disorders in an adult population in northern Norway: A cross-sectional study
    Clinical and Experimental Dental Research 2021 ARKIV / DOI
  • Sini Karinen, Krista Juurikka, Roosa Hujanen, Wafa Whabi, Elin Synnøve Hadler-Olsen, Gunbjørg Svineng m.fl.:
    Tumour cells express functional lymphatic endothelium-specific hyaluronan receptor in vitro and in vivo: Lymphatic mimicry promotes oral oncogenesis?
    Oncogenesis 2021 ARKIV / DOI
  • Elin Synnøve Hadler-Olsen :
    Erfaringer med økonomiske støtteordninger for tannbehandling hos personer som er behandlet for hode-halskreft
    Den norske tannlegeforenings tidende 2021 ARKIV
  • Anna Maria Wirsing, Inger-Heidi Bjerkli, Sonja Eriksson Steigen, Oddveig G Rikardsen, Synnøve Norvoll Magnussen, Beate Hegge m.fl.:
    Validation of Selected Head and Neck Cancer Prognostic Markers from the Pathology Atlas in an Oral Tongue Cancer Cohort
    Cancers 2021 ARKIV / DOI
  • Synnøve Norvoll Magnussen, Jimita Prashant Toraskar, Elin Synnøve Hadler-Olsen, Tonje S. Steigedal, Gunbjørg Svineng :
    Nephronectin as a matrix effector in cancer
    Cancers 25. februar 2021 ARKIV / DOI
  • Synnøve Norvoll Magnussen, Jimita Prashant Toraskar, Imola Wilhelm, Janos Hasko, Stine Figenschau, Judit Molnar m.fl.:
    Nephronectin promotes breast cancer brain metastatic colonization via its integrin-binding domains
    Scientific Reports 2020 ARKIV / DOI
  • Inger-Heidi Bjerkli, Elin Synnøve Hadler-Olsen, Elisabeth Sivy Nginamau, Helene Laurvik, Tine Merete Søland, Daniela Elena Costea m.fl.:
    A combined histo-score based on tumor differentiation and lymphocytic infiltrate is a robust prognostic marker for mobile tongue cancer
    Virchows Archiv 30. juni 2020 ARKIV / DOI
  • Inger-Heidi Bjerkli, Helene Laurvik, Elisabeth Sivy Nginamau, Tine Merete Søland, Daniela Elena Costea, Håkon Hov m.fl.:
    Tumor budding score predicts lymph node status in oral tongue squamous cell carcinoma and should be included in the pathology report
    PLOS ONE 25. september 2020 ARKIV / DOI
  • Meri Sieviläinen, Anna Maria Wirsing, Aini Hyytiäinen, Rabeia Almahmoudi, Priscila Rodrigues, Inger-Heidi Bjerkli m.fl.:
    Evaluation challenges in the validation of B7-H3 as oral tongue cancer prognosticator
    Head and Neck Pathology 21. september 2020 ARKIV / DOI
  • Inger-Heidi Bjerkli, Olav Jetlund, Gunnhild Karevold, Åsa Karlsdottir, Ellen A. Andreassen Jaatun, Lars Uhlin-Hansen m.fl.:
    Characteristics and prognosis of primary treatment-naïve oral cavity squamous cell carcinoma in Norway, a descriptive retrospective study
    PLOS ONE 2020 ARKIV / DOI
  • Sonja Eriksson Steigen, Tine Merete Søland, Elisabeth Sivy Nginamau, Helene Laurvik, Daniela Elena Costea, Anne Christine Johannessen m.fl.:
    Grading of oral squamous cell carcinomas – Intra and interrater agreeability: Simpler is better?
    Journal of Oral Pathology & Medicine 2020 ARKIV / DOI
  • Elin Synnøve Hadler-Olsen, Anna Maria Wirsing :
    Tissue-infiltrating immune cells as prognostic markers in oral squamous cell carcinoma: a systematic review and meta-analysis
    British Journal of Cancer 2019 ARKIV / DOI
  • Elin Synnøve Hadler-Olsen, Jan-Olof Winberg :
    Method for Determining Gelatinolytic Activity in Tissue: In Situ Gelatin Zymography
    Methods in molecular biology 2019 ARKIV / DOI
  • Elin Synnøve Hadler-Olsen, Jan-Olof Winberg :
    Method for Determining Gelatinolytic Activity in Tissue Extracts: Real-Time Gelatin Zymography.
    Methods in molecular biology 2019 ARKIV / DOI
  • Mark Owyong, Jonathan Chou, Renske van den Bijgaart, Niwen Kong, Gizem Efe, Carrie Maynard m.fl.:
    MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy
    Life Science Alliance (LSA) 2019 ARKIV / DOI
  • Steinar Risnes, Qalbi Khan, Elin Synnøve Hadler-Olsen, Amer Sehic :
    Tooth identification puzzle: A method of teaching and learning tooth morphology
    European journal of dental education 2018 DOI
  • Anna Maria Wirsing, Ida Korsnes Ervik, Marit Seppola, Lars Uhlin-Hansen, Sonja Eriksson Steigen, Elin Synnøve Hadler-Olsen :
    Presence of high-endothelial venules correlates with a favorable immune microenvironment in oral squamous cell carcinoma
    Modern Pathology 2018 ARKIV / DOI
  • Pirjo Åström, Krista Juurikka, Elin Synnøve Hadler-Olsen, Gunbjørg Svineng, Nilva K. Cervigne, Ricardo D. Coletta m.fl.:
    The interplay of matrix metalloproteinase-8, transforming growth factor-β1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma
    British Journal of Cancer 2017 ARKIV / DOI
  • Synnøve Magnussen, Elin Synnøve Hadler-Olsen, Daniela Elena Costea, Eli Berg, Cristiane de Albuquerque Cavalcanti Jacobsen, Bente Mortensen m.fl.:
    Cleavage of the urokinase receptor (uPAR) on oral cancer cells: Regulation by transforming growth factor - beta1 (TGF-beta1) and potential effects on migration and invasion
    BMC Cancer 2017 ARKIV / DOI
  • Synnøve Magnussen, Gerd Berge, Ruth Schwienbacher, Anna Maria Wirsing, Elin Synnøve Hadler-Olsen :
    The spatiotemporal immune profile during mouse oral carcinogenesis
    Molecular Oncology 2023 DOI
  • Ruth Schwienbacher, Anna Engan Aamodt, Anna Maria Wirsing, Gerd Berge, Elin Synnøve Hadler-Olsen, Synnøve Magnussen :
    The spatiotemporal immune profile during mouse oral carcinogenesis - high-endothelial venules develop during early stages - and accumulate in late-stage disease
    2023
  • Ruth Schwienbacher, Anna Engan Aamodt, Anna Maria Wirsing, Gerd Berge, Elin Synnøve Hadler-Olsen, Synnøve Magnussen :
    The spatiotemporal immune profile during mouse oral carcinogenesis - high-endothelial venules develop during early stages - and accumulate in late-stage disease
    2023
  • kristina garfjell Kantola, Elin Synnøve Hadler-Olsen, Jan Are Kolset Johnsen, Rolf Wynn :
    Oral health in Norwegian psychiatric inpatients
    2023
  • Elin Synnøve Hadler-Olsen :
    Munn- og halskreft - hva forventes av allmenntannlegen?
    2023
  • Elin Synnøve Hadler-Olsen :
    Pasienten med munn- og halskreft
    2023
  • Rolf Wynn, kristina garfjell Kantola, Elin Synnøve Hadler-Olsen, Jan-Are Kolset Johnsen :
    Oral health in inpatients with psychiatric or substance use disorders
    International Journal of Integrated Care (IJIC) 2022 DOI
  • Elin Synnøve Hadler-Olsen :
    Seneffekter, tannhelse, økonomi og livskvalitet
    2022
  • Elin Synnøve Hadler-Olsen, Marit Aaby Vebenstad :
    Sårbare pasienter må dekke egen tannbehandling
    08. desember 2021 FULLTEKST
  • Kristina Garfjell Kantola, Elin Synnøve Hadler-Olsen, Jan-Are Kolset Johnsen, Rolf Wynn :
    ORAL HEALTH IN INPATIENTS WITH PSYCHIATRIC OR SUBSTANCE USE DISORDERS
    2021
  • Elin Synnøve Hadler-Olsen, Therese Bondø, Lene Marita Steinvik :
    Forsker på tannhelse blant unge
    06. juli 2021
  • Kristina Garfjell Kantola, Jan-Are Kolset Johnsen, Elin Synnøve Hadler-Olsen, Rolf Wynn :
    DENTAL COMORBIDITY IN A PSYCHIATRIC INPATIENT POPULATION
    2021
  • Elin Synnøve Hadler-Olsen, Bondø Therese, Andreas Jörn Schmalfuss, Veronica Turange, Anne Sofie Rønnfeldt, Lene Marita Steinvik :
    Unge drar ikke til tannlegen: – Kvier seg for regninga
    05. juli 2021 FULLTEKST
  • Vibeke Hervik Bull, Elin Synnøve Hadler-Olsen, Ellen Berggreen, Astrid Jullumstrø Feuerherm, Vibeke Elise Ansteinsson :
    De odontologiske kompetansesentrene satser på forskning på sårbare grupper for å redusere ulikheter i oral helse
    Den norske tannlegeforenings tidende 2021
  • Abdelhakim Salem, Elin Synnøve Hadler-Olsen, Ahmed Al-Samadi :
    Editorial: Angiogenesis and Angiogenesis Inhibitors in Oral Cancer
    Frontiers in Oral Health 2021 FULLTEKST / DOI
  • Elin Synnøve Hadler-Olsen, Anna Maria Wirsing :
    Reply to ‘Comment on “Tissue-infiltrating immune cells as prognostic markers in oral squamous cell carcinoma: a systematic review and meta-analysis”’
    British Journal of Cancer 2019 DOI
  • Elin Synnøve Hadler-Olsen :
    Forsker vil ha rettferdighet for munn- og halskreftpasienter
    13. september 2019 FULLTEKST
  • Elin Synnøve Hadler-Olsen, Are Rydland :
    Når behandlingsskader blir problemet
    Morgenbladet 17. oktober 2018
  • Elin Synnøve Hadler-Olsen :
    High Endothelial venules and inflammation in oral squamous cell carcinoma
    2018
  • Synnøve Magnussen, Jimita Prashant Toraskar, Imola Wilhelm, Janos Hasko, Stine Figenschau, Judith Molnar m.fl.:
    Nephronectin promotes breast cancer brain metastatic colonization via its integrin-binding domains
    2018
  • Sonja Eriksson Steigen, Anna Maria Wirsing, Elin Synnøve Hadler-Olsen, Lars Uhlin-Hansen, Marit Seppola, Ida Korsnes Ervik :
    Oral cancer and high endothelial venules (HEV)
    2017
  • Elin Synnøve Hadler-Olsen, Hans Thomas Brox, Eva-Britta Thode Hansen :
    Kirurgi uten kirurg - spesialistens råd til allmenntannlegen
    2017

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    Forskningsinteresser

    Munnhulekreft
    Tumorbiologi
    Oral helse


    Min interesse og forskning innen munnhulekreft spenner fra prosjekter rundt tumorbiologi/immunologi og prognostiske markører til livskvalitet, rehabilitering og oppfølging av senskader etter behandling. Jeg har også forskningsprosjekter rundt munnhelse og bruk av tannhelsetjenester både i befolkningen generelt og hos utsatte grupper. 

    Undervisning

    Oral anatomi og patologi


    Medlem i forskningsgruppe



    CV

    Forskningsleder Tannhelsetjenestens kompetansesenter for Nord-Norge 2020-

    Professor IMB 2018-

    Instituttleder IKO 2018-2020

    Visiting researcher UCSF, department of Anatomy, Prof. Zena Werb's lab 2015-2016

    Tannlege Avdeling for klinisk patologi, Universitetssykehuset i Nord-Norge 2014-2019

    Tannlege med veilederfunksjon Universitetstanklinikken i Tromsø, 2012-2014

    Førsteamanuensis i oral anatomi, IMB  2010- 2018

    Phd Universitetet i Tromsø, Institutt for medisinsk biokjemi 2010:  "Oral and Skin Squamous cell carcinomas - Role of the Microenvironment in Tumor Progression"

    Privatpraktiserende tannlege i Tromsø 2007-2010

    Stipendiat Universitetet i Tromsø, Institutt for medisinsk biologi, 2005-2010

    Tannlege Tromsø tannhelsedistrikt 1999-2005

    Tannlege Stavanger tannhelsedistrikt 1998-1999

    Cand odont Universitetet i Bergen 1998



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