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Bilde av Aasum, Ellen
Bilde av Aasum, Ellen
Institutt for medisinsk biologi ellen.aasum@uit.no +4777646486 99372997 Her finner du meg

Ellen Aasum

Professor

Stillingsbeskrivelse

 

For more information, please visit the English site.

  • Synne Hansen, Tina Myhre Pedersen, Julie Marin, Neoma Tove Boardman, Ajay M. Shah, Ellen Aasum m.fl.:
    Overexpression of NOX2 Exacerbates AngII‐Mediated Cardiac Dysfunction and Metabolic Remodelling
    Antioxidants 2022 ARKIV / DOI
  • Neoma Tove Boardman, Tina Myhre Pedersen, Line Rossvoll, Anne Dragøy Hafstad, Ellen Aasum :
    Diet-induced obese mouse hearts tolerate an acute high fatty acid exposure that also increases ischemic tolerance
    American Journal of Physiology. Heart and Circulatory Physiology 2020 ARKIV / DOI
  • Anne Dragøy Hafstad, Synne Simonsen Hansen, Jim Lund, Celio X.C. Santos, Neoma Tove Boardman, Ajay M. Shah m.fl.:
    NADPH oxidase 2 mediates myocardial oxygen wasting in obesity
    Antioxidants 2020 ARKIV / DOI
  • Neoma Tove Boardman, Line Rossvoll, Jim Lund, Anne Dragøy Hafstad, Ellen Aasum :
    3-Weeks of Exercise Training Increases Ischemic-Tolerance in Hearts From High-Fat Diet Fed Mice
    Frontiers in Physiology 02. oktober 2019 ARKIV / DOI
  • Tina Myhre Pedersen, Neoma Boardman, Anne Dragøy Hafstad, Ellen Aasum :
    Isolated perfused working hearts provide valuable additional information during phenotypic assessment of the diabetic mouse heart
    PLOS ONE 2018 ARKIV / DOI
  • Synne Simonsen Hansen, Ellen Aasum, Anne Dragøy Hafstad :
    The role of NADPH oxidases in diabetic cardiomyopathy
    Biochimica et Biophysica Acta - Molecular Basis of Disease 2018 ARKIV / DOI
  • Neoma Boardman, Anne Dragøy Hafstad, Jim Lund, Line Rossvoll, Ellen Aasum :
    Exercise of obese mice induces cardioprotection and oxygen sparing in hearts exposed to high-fat load
    American Journal of Physiology. Heart and Circulatory Physiology 2017 DOI
  • Adam A. Nabeebaccus, Anna Zoccarato, Anne Dragøy Hafstad, Celio X.C. Santos, Ellen Aasum, Alison C. Brewer m.fl.:
    Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation
    JCI Insight 2017 DOI
  • Latt S. Mansor, Keshavi Metha, Dunja Aksentijevic, Carolyn A. Carr, trine Lund, Mark A. Cole m.fl.:
    Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation
    Journal of Physiology 2016 DOI
  • Wahida Salma, Veronika Franeková, trine Lund, Anje Christina Höper, Stian Ludvigsen, Jim Lund m.fl.:
    Dietary Calanus oil antagonizes angiotensin II-induced hypertension and tissue wasting in diet-induced obese mice
    Prostaglandins, Leukotrienes and Essential Fatty Acids 2016 DOI
  • Mark A. Cole, Amira H. Abd Jamil, Lisa C Heather, Andrew J Murray, Elizabeth R Sutton, Mary Slingo m.fl.:
    On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury
    The FASEB Journal 2016 DOI
  • Jim Lund, Anne Dragøy Hafstad, Neoma Tove Boardman, Line Rossvoll, Natale Pinheiro Lage Rolim, Muhammad Shakil Ahmed m.fl.:
    Exercise training promotes cardioprotection through oxygen-sparing action in high fat-fed mice
    American Journal of Physiology. Heart and Circulatory Physiology 2015 DOI
  • Anne Dragøy Hafstad, Neoma Tove Boardman, Ellen Aasum :
    How Exercise May Amend Metabolic Disturbances in Diabetic Cardiomyopathy
    Antioxidants and Redox Signaling 2015 ARKIV / DOI
  • Jens Petter Bakkehaug, Anders Benjamin Kildal, Erik Torgersen Engstad, Neoma Tove Boardman, Torvind Næsheim, Leif R. Rønning m.fl.:
    Myosin activator omecamtiv mecarbil increases myocardial oxygen consumption and impairs cardiac efficiency mediated by resting myosin ATPase activity
    Circulation: Heart Failure 2015 DOI
  • Neoma Tove Boardman, Jan Magnus Aronsen, William Edward Louch, Ivar Sjaastad, Frode Willoch, Geir Arve Christensen m.fl.:
    Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2
    American Journal of Physiology. Heart and Circulatory Physiology 2014 ARKIV / DOI
  • Anje Christina Höper, Wahida Salma, Selene Julie Sollie, Anne Dragøy Hafstad, Jim Lund, Ahmed Murtaz Khalid m.fl.:
    Wax esters from the marine copepod calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice
    Journal of Nutrition 2014 DOI
  • Neoma Tove Boardman, Jan Magnus Aronsen, William Edward Louch, Ivar Sjaastad, Frode Willoch, Geir Arve Christensen m.fl.:
    Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2
    American Journal of Physiology. Heart and Circulatory Physiology 2014 DOI
  • Ellen Aasum :
    Relationship Between Substrate Metabolism and Cardiac Efficiency
    Springer Science+Business Media B.V. 2014 DOI
  • Anje Christina Höper, Wahida Salma, Ahmed Murtaz Khalid, Anne Dragøy Hafstad, Selene Julie Sollie, Jan Raa m.fl.:
    Oil from the marine zooplankton Calanus finmarchicus improves the cardiometabolic phenotype of diet-induced obese mice
    British Journal of Nutrition 2013 DOI
  • Anne Dragøy Hafstad, Jim Lund, Elin Synnøve Hadler-Olsen, Anje Christina Höper, Terje Larsen, Ellen Aasum :
    High- and Moderate-Intensity Training Normalizes Ventricular Function and Mechanoenergetics hi Mice With Diet-Induced Obesity
    Diabetes 2013 DOI
  • Thomas Gero von Lueder, Jørgen A. Gravning, Ole-Jakob How, Leif Erik Vinge, Muhammad Shakil Ahmed, Kurt Allen Krobert m.fl.:
    Cardiomyocyte-restricted inhibition of G protein-coupled receptor kinase-3 attenuates cardiac dysfunction after chronic pressure overload
    American Journal of Physiology. Heart and Circulatory Physiology 2012 DOI
  • Ellen Aasum :
    Myocardial energetics and efficiency
    Hearts and Metabolism 2011
  • Ahmed Murtaz Khalid, Anne Dragøy Hafstad, Terje Larsen, david lester Severson, Neoma Tove Boardman, Martin Hagve m.fl.:
    Cardioprotective effect of the PPAR ligand tetradecylthioacetic acid in type 2 diabetic mice
    American Journal of Physiology. Heart and Circulatory Physiology 2011 DOI
  • Neoma Tove Boardman, Terje Larsen, david lester Severson, M Fadiel Essop, Ellen Aasum :
    Chronic and acute exposure of mouse hearts to fatty acids increases oxygen cost of excitation-contraction coupling
    American Journal of Physiology. Heart and Circulatory Physiology 2011 DOI
  • Anne Dragøy Hafstad, Neoma Tove Boardman, Jim Lund, Martin Hagve, Ahmed Murtaz Khalid, Ulrik Wisløff m.fl.:
    High intensity interval training alters substrate utilization and reduces oxygen consumption in the heart
    Journal of applied physiology 2011 DOI
  • Ellen Aasum :
    Obesity/diabetes-induced alterations in cardiac metabolism and mechanoenergetics
    2023
  • Jens Petter Bakkehaug, Anders Benjamin Kildal, Erik Torgersen Engstad, Neoma Tove Boardman, Torvind Næsheim, Leif R. Rønning m.fl.:
    Response to Letter Regarding Article, "Myosin Activator Omecamtiv Mecarbil Increases Myocardial Oxygen Consumption and Impairs Cardiac Efficiency Mediated by Resting Myosin ATPase Activity"
    Circulation: Heart Failure 2015 DOI
  • Anne Dragøy Hafstad, Ellen Aasum, Jim Lund, Santos Celio X, Ajay Shah :
    A role of NADPH oxidase in obesity-induced myocardial oxygen wasting
    2015
  • Ellen Aasum :
    Exercise and its beneficial role on the diabetic heart
    2014
  • Ellen Aasum :
    Cardiac efficiency and mechanoenergetics in diabetic cardiomyopathy
    2014
  • Ellen Aasum :
    Cardiac Efficiency and Mechanoenergetics in Diabetic Cardiomyopathy
    2014
  • Jim Lund, Ellen Aasum :
    The effect of nitrate/nitrite on cardiac energetics
    2014
  • Anne Dragøy Hafstad, Jim Lund, Ellen Aasum, Celio X Santos, Ajay Shah :
    A role of NADPH oxidase in obesity-induced myocardial oxygen wasting
    2014
  • Anne Dragøy Hafstad, Jim Lund, Ellen Aasum, C Santos, Ajay Shah :
    Prevention of obesity-induced myocardial oxygen-wasting through NADPH-oxidase inhibition
    2013
  • Wahida Salma, Anje Christina Höper, trine Lund, Stian Ludvigsen, Kirsti Ytrehus, Ellen Aasum m.fl.:
    Dietary supply with Calanus oil antagonizes angiotensin IIinduced hypertension, cardiac hypertrophy and cachexia in obese mice
    2013
  • Anne Dragøy Hafstad, Jim Lund, Martin Hagve, Elin Synnøve Hadler-Olsen, Anje Christina Höper, Terje Larsen m.fl.:
    High and moderate intensity training prevent diet-induced impairments in cardiac mechanoenergetics and ventricular function
    2012
  • Anje Christina Höper, Terje Larsen, Ahmed Murtaz Khalid, Wahida Salma, Selene Julie Sollie, Jim Lund m.fl.:
    Low-dose supplementation with Calanus oil attenuates visceral adiposity and low-grade inflammation during high fat feeding
    2012
  • Jim Lund, Anne Dragøy Hafstad, Terje Larsen, Ellen Aasum :
    High and moderate intensity training prevent obesity-related oxygen waste and development of left ventricular dysfunction in the presence of high fat
    2012
  • Ellen Aasum :
    Diabetic cardiomyopathy - metabolic interventions and exercise
    2012
  • Anne Dragøy Hafstad, Jim Lund, Terje Larsen, Ellen Aasum :
    Cardiovascular Research Group, Faculty of Health Sciences, University of Tromsø, Norway. Exercise training prevent obesity-induced impairment of myocardial function and mechanoenergetics, as well as mitochondrial capacity and fatty acid-induced proton leak
    2012
  • Wahida Salma, Anje Christina Höper, Ahmed Murtaz Khalid, Selene Julie Sollie, Jim Lund, Anne Dragøy Hafstad m.fl.:
    Wax ester purified from Calanus oil reduces visceral obesity and low-grade inflammation in adipose tissue during high fat feeding
    2012
  • Wahida Salma, Selene Julie Sollie, Anje Christina Höper, Ahmed Murtaz Khalid, Jim Lund, Anne Dragøy Hafstad m.fl.:
    Dietary supplementation with Calanus oil reduces visceral fat deposition and improves insulin sensitivity during high fat feeding
    2012
  • Neoma Tove Boardman, Ellen Aasum :
    Cardiometabolic adaptations to altered fuel supply, Ca2+ handling and exercise
    UiT Norges arktiske universitet 2011
  • Anne Dragøy Hafstad, Jim Lund, Anje Christina Høper, Elin Synnøve Hadler-Olsen, Martin Hagve, Ulrik Wisløff m.fl.:
    Exercise improves ventricular function and decreases myocardial oxygen waste in diet-induced obese mice
    2011
  • Anje Christina Høper, Terje Larsen, Jim Lund, Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Ellen Aasum :
    Oil extracted from the marine copepod Calanus finmarchicus reduces diet-induced obesity and insulin resistance, and improves aerobic capacity in mice
    2011
  • Ellen Aasum :
    Prevention of cardiac inefficiency in type 2 diabetes by means of high-intensity exercise training
    2011
  • Ellen Aasum :
    Heart function and metabolism in type 2 diabetic db/db mice
    2011
  • Anne Dragøy Hafstad, Jim Lund, Anje Christina Høper, Elin Synnøve Hadler-Olsen, Martin Hagve, Ulrik Wisløff m.fl.:
    High intensity interval training normalizes cardiac energetics and ventricular function in diet-induced obese mice
    2011
  • Martin Hagve, Espen Sanden, Ellen Aasum, Terje Larsen :
    Palmitate-induced uncoupling reduces oxidative stress in cardiac mitochondria respiring on complex II substrate
    2011
  • Anne Dragøy Hafstad, Jim Lund, Anje Christina Høper, Elin Synnøve Hadler-Olsen, Martin Hagve, Ulrik Wisløff m.fl.:
    Exercise improves ventricular function and decreases myocardial oxygen waste in diet-induced obese mice
    Circulation 2011

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