Bilde av Smedsrød, Bård
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Bilde av Smedsrød, Bård
Institutt for medisinsk biologi bsm000@post.uit.no +4777644687 Her finner du meg

Bård Smedsrød


Professor emeritus / arbeidspakkeleder i NFR-prosjektet LUPCON

Stillingsbeskrivelse

Professor emeritus / arbeidspakkeleder i NFR-prosjektet LUPCON


  • Javier Sánchez Romano, Jaione Simon-Santamaria, Peter Anthony McCourt, Bård Helge Smedsrød, Kim Erlend Mortensen, Antonia Sagona m.fl.:
    Liver sinusoidal cells eliminate blood-borne phage K1F
    mSphere 2024 DOI
  • Julian Philipp, Aleksandra Dabkowska, Anita Reiser, Kilian Frank, Rafał Krzysztoń, Christiane Brummer m.fl.:
    pH-dependent structural transitions in cationic ionizable lipid mesophases are critical for lipid nanoparticle function
    Proceedings of the National Academy of Sciences of the United States of America 2023 ARKIV / DOI
  • Milton Boaheng Antewi, Gianina Aurica Dumitriu, Jaione Santamaria Simon, Javier Sanchez Romano, Ruomei Li, Bård Smedsrød m.fl.:
    Liver sinusoidal endothelial cells show reduced scavenger function and downregulation of Fc gamma receptor IIb, yet maintain a preserved fenestration in the Glmp gt/gt mouse model of slowly progressing liver fibrosis
    PLOS ONE 2023 ARKIV / DOI
  • Ruomei Li, Sabin Bhandari, Inigo Zubiavrre Martinez, Jack-Ansgar Bruun, Ilona Halva Urbarova, Bård Smedsrød m.fl.:
    Changes in the proteome and secretome of rat liver sinusoidal endothelial cells during early primary culture and effects of dexamethasone
    PLOS ONE 2022 ARKIV / DOI
  • Kjetil Elvevold, Ingelin Kyrrestad, Bård Smedsrød :
    Protocol for Isolation and Culture of Mouse Hepatocytes (HCs), Kupffer Cells (KCs), and Liver Sinusoidal Endothelial Cells (LSECs) in Analyses of Hepatic Drug Distribution
    Methods in molecular biology 2022 ARKIV / DOI
  • Anett Kristin Larsen, Jaione Simon-Santamaria, kjetil helge Elvevold, Bo Gøran Ericzon, Kim Erlend Mortensen, Peter Anthony McCourt m.fl.:
    Autofluorescence in freshly isolated adult human liver sinusoidal cells
    European journal of histochemistry 2021 ARKIV / DOI
  • Sabin Bhandari, Anett Kristin Larsen, Peter Anthony McCourt, Bård Smedsrød, Karen Kristine Sørensen :
    The scavenger function of liver sinusoidal endothelial cells in health and disease
    Frontiers in Physiology 11. oktober 2021 ARKIV / DOI
  • Karen Kristine Sørensen, Bård Smedsrød :
    The Liver Sinusoidal Endothelial Cell: Basic Biology and Pathobiology
    John Wiley & Sons 2020
  • Cristina Ionica Øie, Deanna Wolfson, Tanji Yasunori, Gianina Dumitriu, Karen Kristine Sørensen, Peter Anthony McCourt m.fl.:
    Liver sinusoidal endothelial cells contribute to the uptake and degradation of entero bacterial viruses.
    Scientific Reports 2020 ARKIV / DOI
  • Willeke De Haan, Cristina Ionica Øie, Mohammed Benkheil, Wouter Dheedene, Stefan Vinckier, Giulia Coppiello m.fl.:
    Unraveling the transcriptional determinants of liver sinusoidal endothelial cell specialization
    American Journal of Physiology - Gastrointestinal and Liver Physiology 2020 DOI
  • Sabin Bhandari, Ruomei Li, Jaione Simon-Santamaria, Peter Anthony McCourt, Steinar Daae Johansen, Bård Smedsrød m.fl.:
    Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages
    BMC Molecular and Cell Biology 2020 ARKIV / DOI
  • Wiebke Albrecht, Franziska Kappenberg, Tim Brecklinghaus, Regina Stoeber, Rosemarie Marchan, Mian Zhang m.fl.:
    Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations
    Archives of Toxicology 2019 ARKIV / DOI
  • Richard England, Jennifer Moss, Kathryn J Hill, kjetil helge Elvevold, Bård Smedsrød, Marianne B Ashford :
    Evaluating liver uptake and distribution of different poly(2-methyl-2-oxazoline) modified lysine dendrimers following intravenous administration
    Biomaterials Science 2019 DOI
  • Aitor Benedicto, Alba Herrero, Irene Romayor, Joana Marquez, Bård Smedsrød, Elvira Olaso m.fl.:
    Liver sinusoidal endothelial cell ICAM-1 mediated tumor/endothelial crosstalk drives the development of liver metastasis by initiating inflammatory and angiogenic responses
    Scientific Reports 2019 ARKIV / DOI
  • Kalle Sigfridsson, Pia Skantze, Urban Skantze, Lena Svensson, Lars Lofgren, Pär Nordell m.fl.:
    Nanocrystal formulations of a poorly soluble drug. 2. Evaluation of nanocrystal liver uptake and distribution after intravenous administration to mice
    International Journal of Pharmaceutics 2017 DOI
  • Leif Longva, Eirik Reierth, Lars Moksness, Bård Smedsrød :
    Peer reviewing: a private affair between the individual researcher and the publishing houses, or a responsibility of the university?
    Journal of Electronic Publishing 22. mai 2017 ARKIV / DOI
  • Caroline Godfrey, Lourdes R. Desviat, Bård Smedsrød, France Piétri-Rouxel, Michela A. Denti, Petra Disterer m.fl.:
    Delivery is key: lessons learnt from developing splice-switching antisense therapies
    EMBO Molecular Medicine 2017 ARKIV / DOI
  • Kalle Sigfridsson, Urban Skantze, Pia Skantze, Svante Johansson, Iain Grant, Bård Smedsrød m.fl.:
    Nanocrystal formulations of a poorly soluble drug. 1. In vitro characterization of stability, stabilizer adsorption and uptake in liver cells
    International Journal of Pharmaceutics 2017 DOI
  • Cristina Ionica Øie, Kirstine Roepstorff, Carsten Behrens, Jesper Bøggild Kristensen, Ditte Maria Karpf, Gert Bolt m.fl.:
    High-affinity von Willebrand factor binding does not affect the anatomical or hepatocellular distribution of factor VIII in rats
    Journal of Thrombosis and Haemostasis 2016 ARKIV / DOI
  • Geir Ivar Nedredal, Kjetil Helge Elvevold, MF Chedid, Lars Marius Ytrebø, CF Rose, S Sen m.fl.:
    Pulmonary vascular clearance of harmful endogenous macromolecules in a porcine model of acute liver failure
    Annals of Hepatology 2016 SAMMENDRAG / ARKIV / DOI
  • Cristina Ionica Øie, Igor Snapkov, Kjetil Elvevold, Baldur Sveinbjørnsson, Bård Smedsrød :
    FITC conjugation markedly enhances hepatic clearance of N-formyl peptides
    PLOS ONE 2016 ARKIV / DOI
  • Karen Kristine Sørensen, Jaione Simon-Santamaria, Robert S. McCuskey, Bård Smedsrød :
    Liver sinusoidal endothelial cells
    Comprehensive Physiology 2015 DOI
  • Adil El Taghdouini, Anita Løvstad Sørensen, Andrew Henry Reiner, Mar Coll, Stefaan Verhulst, Inge Mannaerts m.fl.:
    Genome-wide analysis of DNA methylation and gene Expression patterns in purified, uncultures human liver cells and activated hepatic stellate cells
    OncoTarget 2015 ARKIV / DOI
  • Jaione Simon-Santamaria, Christine Hanssen Rinaldo, Piotr Kardas, Ruomei Li, Ivana Malovic, kjetil helge Elvevold m.fl.:
    Efficient uptake of blood-borne BK and JC polyomavirus-like particles in endothelial cells of liver sinusoids and renal vasa recta
    PLOS ONE 2014 ARKIV / DOI
  • Viola Mönkemöller, Mark Schuttpelz, Peter Anthony McCourt, Karen Kristine Sørensen, Bård Smedsrød, Thomas Rolf Huser :
    Imaging fenestrations in liver sinusoidal endothelial cells by optical localization microscopy
    Physical Chemistry, Chemical Physics - PCCP 07. mai 2014 DOI
  • Anett Kristin Larsen, Javier Sanchez Romano, Jaione Santamaria Simon, Kim Erlend Mortensen, Ingelin Kyrrestad Karlstrøm, Eirik Abrahamsen Lænsman m.fl.:
    Liver sinusoidal scavenger cells eliminate betaherpesvirus from the blood stream.
    Journal of Hepatology 2023 DOI
  • Javier Sanchez Romano, Jaione Santamaria Simon, Peter Anthony Gerard Mccourt, Christopher Florian Holte, Bård Smedsrød, Antonia Sagona m.fl.:
    Rapid blood clearance of phage K1F-GFP is mediated by the liver and executed by Kupffer cells and liver sinusoidal endothelial cells in collaboration
    2023
  • Anett Kristin Larsen, Javier Sanchez Romano, Eirik Abrahamsen Lænsman, Anne Lotte Vada Hatlegjerde, Jaione Simon-Santamaria, Kim Erlend Mortensen m.fl.:
    Liver sinusoidal scavenger cells eliminate betaherpesvirus from the blood stream
    2022
  • Javier Sanchez Romano, Anett Kristin Larsen, Jaione Simon-Santamaria, Cristina Ionica Øie, Bård Smedsrød, Peter Anthony McCourt m.fl.:
    The role of scavenger endothelial cells in bacteriophage pharmacokinetics
    2022
  • Javier Sanchez Romano, Anett Kristin Larsen, Jaione Simon-Santamaria, Cristina Ionica Øie, Bård Smedsrød, Peter Anthony McCourt m.fl.:
    The role of scavenger endothelial cells in bacteriophage pharmacokinetics
    2022
  • Anett Kristin Larsen, Javier Sanchez Romano, Jaione Simon-Santamaria, Kim Erlend Mortensen, Bo Gøran Ericzon, Peter Anthony McCourt m.fl.:
    Role of liver sinusoidal endothelial cells in elimination of virus
    2022
  • Leif Longva, Bård Smedsrød :
    Stans gratisarbeidet for grådige tidsskriftsforlag
    Khrono.no 26. desember 2021 ARKIV
  • Bård Smedsrød :
    Old drugs to reinvigorate old liver cells
    The journals of gerontology. Series A, Biological sciences and medical sciences 2020 DOI
  • Anett Kristin Larsen, Jaione Simon-Santamaria, kjetil helge Elvevold, Bo G. Ericzon, Bård Smedsrød, Karen Kristine Sørensen :
    Autofluorescence in freshly isolated adult human liver sinusoidal cells
    2019
  • Sabin Bhandari, Ruomei Li, Ingelin Kyrrestad, Jack-Ansgar Bruun, Ilona Urbarova, Bård Smedsrød m.fl.:
    Effect of glucocorticoids on liver sinusoidal endothelial cells in vitro
    2019
  • Javier Sanchez Romano, Anett Kristin Larsen, kjetil helge Elvevold, Christopher Florian Holte, Jaione Simon-Santamaria, Hans H. Hirsch m.fl.:
    SECVIR - The role of scavenger endothelial cells in elimination of virus
    2019
  • Ingelin Kyrrestad, Ruomei Li, Sabin Bhandari, Jaione Simon-Santamaria, Bård Smedsrød, Karen Kristine Sørensen :
    A protocol for in vitro toxicity studies in liver sinusoidal endothelial cells
    2019
  • Karen Kristine Sørensen, Milton Boaheng Antwi, Gianina Dumitriu, Ruomei Li, Bård Smedsrød, Winnie Eskild :
    Scavenger function of liver sinusoidal endothelial cells in a transgenic mouse model of liver fibrosis is reduced
    2019
  • Leif Longva, Jan Erik Frantsvåg, Bård Smedsrød :
    Plan S og implementering
    Khrono.no 05. november 2018 ARKIV / FULLTEKST
  • Bård Smedsrød :
    Episode #9 I serien Nå Er Det Alvor: Bård Smedsrød - en mann som lever for å levere
    02. mars 2018 DATA
  • Bård Smedsrød :
    Carnivore-dietten, fasting, sukker, helsetrender, vitaminer, mineraler + +
    21. juli 2018 DATA
  • Bård Smedsrød :
    The problem with peer review
    23. oktober 2018 DATA
  • Bård Smedsrød, Leif Longva, Jan Erik Frantsvåg :
    Voldsom sløsing med offentlige penger i vitenskapelig publisering
    Dagens næringsliv 28. februar 2018 ARKIV
  • Deanna Wolfson, Cristina Ionica Øie, Tanji Yasunori, Gianina Dumitriu, Peter Anthony McCourt, Karen Kristine Sørensen m.fl.:
    Uptake and Degradation of Bacteriophages by Liver Sinusoidal Endothelial Cells
    2018 ARKIV
  • Deanna Wolfson, Cristina Ionica Øie, Yasunori Tanji, Karen Kristine Sørensen, Peter Anthony McCourt, Bård Smedsrød m.fl.:
    Multimodal Microscopy to Study the Fate of Bacteriophages in Liver Sinusoidal Endothelial Cells
    2017
  • Sabin Bhandari, Ruomei Li, Jaione Simon-Santamaria, Peter Anthony McCourt, Steinar Daae Johansen, Bård Smedsrød m.fl.:
    The liver sinusoidal endothelial cell – an endothelial cell with a macrophage-like identity
    2017
  • Ruomei Li, Jaione Simon-Santamaria, Sabin Bhandari, Jack-Ansgar Bruun, Ilona Urbarova, Bård Smedsrød m.fl.:
    Phenotypic changes in rat liver sinusoidal endothelial cells during early stages of in vitro culture
    2017
  • Jaione Simon-Santamaria, Ruomei Li, Sabin Bhandari, Jack-Ansgar Bruun, Bård Smedsrød, Inigo Zubiavrre Martinez m.fl.:
    Secretome of the liver sinusoidal endothelial cell
    2016
  • Sabin Bhandari, Ruomei Li, Jaione Simon-Santamaria, Peter Anthony McCourt, Steinar Daae Johansen, Bård Smedsrød m.fl.:
    Next generation deep sequencing of rat liver sinusoidal endothelial cell and Kupffer cell transcriptomes suggests functional complementarity
    2016
  • Jaione Simon-Santamaria, Christine H Rinaldo, Piotr Kardas, Ruomei Li, Ivana Malovic, Kjetil H. Elvevold m.fl.:
    Role of scavenger endothelial cells in polyomavirus JC and BK clearance
    2014

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    Forskningsinteresser

    Role of the scavenger endothelial cell of the vertebrate kingdom, in particular the mammalian liver sinusoidal endothelial cell, in the clearance of colloids and nano particles from the blood circulation.


    Medlem i prosjekt