Bilde av Sanchez Romano, Javier
Bilde av Sanchez Romano, Javier
Institutt for medisinsk biologi javier.s.romano@uit.no +4777625221 +47 4567 1911 Her finner du meg

Javier Sanchez Romano


Postdoktor

Stillingsbeskrivelse

Javier is a veterinary virologist employed in the SECVIR project. In this project, he is studyin the role of the liver sinusoidal endothelial cells (LSECs) as a central player in the cellular arm of the anti-viral innate immune system. In other words, how LSECs take up and eliminate virus from the blood stream. At the same time, Javier has been involved in teaching (MBI-2104 and MBI-3014) and supervision of students.

Besides his work at the Vascular Biology research group, he is a collaborator in the NORHED II project "Climate Change and Infectious Diseases - A One Health Approach (CIDIMOH)" project for the period 2021-2026, which aims to address climate change and infection biology in Uganda and South Sudan. Javier is also a collaborator in the NFR project "Animal welfare, behaviour, health and sustainability – the effects of feeding on reindeer and reindeer herding", which will investigate the short- and long-term effects of supplementary feeding of semi-domesticated reindeer. He has also received a grant from the University of the Arctic with the aim to develop a master's level course in One Health in Northern Communities and Ecosystems.


  • Ingelin Kyrrestad Karlstrøm, Anett Kristin Larsen, Javier Sanchez Romano, Jaione Santamaria Simon, Ruomei Li, Karen Kristine Sørensen :
    Infection of liver sinusoidal endothelial cells with Muromegalovirus muridbeta1 involves binding to neuropilin-1 and is dynamin-dependent
    Frontiers in Cellular and Infection Microbiology 2023 ARKIV / DOI
  • Alaka Lamsal, Morten Tryland, Katrine M. Paulsen, Javier Sanchez Romano, Ingebjørg H. Nymo, Karin Stiasny m.fl.:
    Serological screening for tick-borne encephalitis virus in eight Norwegian herds of semi-domesticated reindeer (Rangifer tarandus tarandus)
    Zoonoses and Public Health 2023 ARKIV / DOI
  • Morten Tryland, Javier Sanchez Romano, Ingebjørg Helena Nymo, Torill Mørk, Rán Þórarinsdóttir, Eva Marie Breines m.fl.:
    A Screening for Virus Infections among Wild Eurasian Tundra Reindeer (Rangifer tarandus tarandus) in Iceland, 2017–2019
    Viruses 2023 ARKIV / DOI
  • Karin Wallin Philippot, Jerome Baron, Javier Sanchez Romano, Heidi Rautiainen, Jenny Frössling, Ingebjørg Helena Nymo m.fl.:
    Infectious keratoconjunctivitis in semi-domesticated reindeer (Rangifer tarandus tarandus): a questionnaire-based study among reindeer herders in Norway and Sweden
    Acta Veterinaria Scandinavica (AVS) 2023 ARKIV / DOI
  • Milton Boaheng Antewi, Gianina Aurica Dumitriu, Jaione Santamaria Simon, Javier Sanchez Romano, Ruomei Li, Bård Smedsrød m.fl.:
    Liver sinusoidal endothelial cells show reduced scavenger function and downregulation of Fc gamma receptor IIb, yet maintain a preserved fenestration in the Glmp gt/gt mouse model of slowly progressing liver fibrosis
    PLOS ONE 2023 ARKIV / DOI
  • Ruchika Shakya, Morten Tryland, Rose Vikse, Javier Sanchez Romano, Kjetil Åsbakk, Ingebjørg Helena Nymo m.fl.:
    Inkoo and Sindbis viruses in blood sucking insects, and a serological study for Inkoo virus in semi-domesticated Eurasian tundra reindeer in Norway
    Virology Journal 2022 ARKIV / DOI
  • Rebecca K. Davidson, Christiane Kruse Fæste, Silvio Uhlig, Feng-Ling Tukun, Hans Edvin Lian, Hans Arne Solvang m.fl.:
    Pharmacokinetics of a long-acting subcutaneous eprinomectin injection in semi-domesticated reindeer (Rangifer tarandus tarandus) - a pilot study
    Environmental Toxicology and Pharmacology 2022 FULLTEKST / ARKIV / DOI
  • Morten Tryland, Birgitta Åhman, Javier Sanchez Romano :
    Health and diseases of semi-domesticated reindeer in a climate change perspective
    Routledge 2022 ARKIV
  • Morten Tryland, Ingebjørg Helena Nymo, Javier Sanchez Romano, Jan Åge Riseth :
    Husbandry and Diseases of Semi-Domesticated Eurasian Tundra Reindeer in Fennoscandia
    Springer Nature 2022 DOI
  • Christine Hanssen Rinaldo, Ingebjørg Helena Nymo, Javier Sanchez Romano, Eva Marie Breines, Francisco Javier Ancin Murguzur, Morten Tryland :
    Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway
    Pathogens 2021 ARKIV / DOI
  • Morten Tryland, Javier Sanchez Romano, Ingebjørg Helena Nymo, Eva Marie Breines, Francisco Javier Ancin Murguzur, Ole Christian Kjenstad m.fl.:
    A Screening for Virus Infections in Eight Herds of Semi-domesticated Eurasian Tundra Reindeer (Rangifer tarandus tarandus) in Norway, 2013–2018
    Frontiers in Veterinary Science 2021 ARKIV / DOI
  • Javier Sanchez Romano, Anna Omazic, Mikael Leijon, Åsa Hagström, Morten Tryland, Juha Kantanen m.fl.:
    Screening of Eurasian Tundra Reindeer for Viral Sequences by Next-Generation Sequencing
    International Journal of Environmental Research and Public Health (IJERPH) 2021 ARKIV / DOI
  • Morten Tryland, Terje D. Josefsen, Javier Sanchez Romano, Nina Marcin, Torill Mørk, Jon M. Arnemo :
    Case Report: Subclinical Verminous Pneumonia and High Ambient Temperatures Had Severe Impact on the Anesthesia of Semi-domesticated Eurasian Tundra Reindeer (Rangifer tarandus tarandus) With Medetomidine–Ketamine
    Frontiers in Veterinary Science 2021 ARKIV / DOI
  • Javier Sanchez Romano, Karen Kristine Sørensen, Anett Kristin Larsen, Torill Mørk, Morten Tryland :
    Ocular Histopathological Findings in Semi-Domesticated Eurasian Tundra Reindeer (Rangifer tarandus tarandus) with Infectious Keratoconjunctivitis after Experimental Inoculation with Cervid Herpesvirus 2
    Viruses 2020 FULLTEKST / ARKIV / DOI
  • Anna Omazic, Caroline Aurosell, Valery Fedorov, Åsa Hagström, Juha Kantanen, Mikael Leijon m.fl.:
    Seroprevalence of pestivirus in Eurasian tundra reindeer in Finland, Sweden, Norway, Iceland and Russian Federation
    Infection Ecology & Epidemiology 2019 ARKIV / DOI
  • Javier Sanchez Romano, Lisa Grund, Anna Obiegala, Ingebjørg Helena Nymo, Francisco Javier Ancin Murguzur, Hong Li m.fl.:
    A Multi-Pathogen Screening of Captive Reindeer (Rangifer tarandus) in Germany Based on Serological and Molecular Assays
    Frontiers in Veterinary Science 2019 ARKIV / DOI
  • Javier Sanchez Romano, Mikael Leijon, Åsa Hagström, Tomas Jinnerot, Urlika Rockström, Morten Tryland :
    Chlamydia pecorum associated with an outbreak of infectious keratoconjunctivitis in semi-domesticated reindeer in Sweden
    Frontiers in Veterinary Science 2019 ARKIV / DOI
  • Morten Tryland, Ingebjørg Helena Nymo, Javier Sanchez Romano, Torill Mørk, Joern Klein, Ulrika Rockström :
    Infectious Disease Outbreak Associated with Supplementary Feeding of Semi-Domesticated Reindeer
    Frontiers in Veterinary Science 2019 ARKIV / DOI
  • Javier Sanchez Romano, Torill Mørk, Sauli Laaksonen, Erik Ågren, Ingebjørg Helena Nymo, Marianne Sunde m.fl.:
    Infectious keratoconjunctivitis in semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus): Microbiological study of clinically affected and unaffected animals with special reference to cervid herpesvirus 2
    BMC Veterinary Research 2018 ARKIV / DOI
  • Morten Tryland, Javier Sanchez Romano, Nina Marcin, Ingebjørg Helena Nymo, Terje D. Josefsen, Karen Kristine Sørensen m.fl.:
    Cervid herpesvirus 2 and not Moraxella bovoculi caused keratoconjunctivitis in experimentally inoculated semi-domesticated Eurasian tundra reindeer
    Acta Veterinaria Scandinavica (AVS) 2017 ARKIV / DOI
  • Anett Kristin Larsen, Javier Sanchez Romano, Jaione Santamaria Simon, Kim Erlend Mortensen, Ingelin Kyrrestad Karlstrøm, Eirik Abrahamsen Lænsman m.fl.:
    Liver sinusoidal scavenger cells eliminate betaherpesvirus from the blood stream.
    Journal of Hepatology 2023 DOI
  • Ingelin Kyrrestad Karlstrøm, Anett Kristin Larsen, Javier Sanchez Romano, Jaione Santamaria Simon, Ruomei Li, Karen Kristine Sørensen :
    The dynamin-inhibitor dynasore blocks cytomegalovirus infection in primary mouse liver sinusoidal endothelial cells
    2023
  • Ingelin Kyrrestad Karlstrøm, Anett Kristin Larsen, Javier Sanchez Romano, Jaione Santamaria Simon, Ruomei Li, Karen Kristine Sørensen :
    Dynamin-inhibitors dynasore and MitMAB block muromegalovirus muridbeta1 infection in liver sinusoidal endothelial cells.
    2023
  • Javier Sanchez Romano, Jaione Santamaria Simon, Peter Anthony Gerard Mccourt, Christopher Florian Holte, Bård Smedsrød, Antonia Sagona m.fl.:
    Rapid blood clearance of phage K1F-GFP is mediated by the liver and executed by Kupffer cells and liver sinusoidal endothelial cells in collaboration
    2023
  • Javier Sanchez Romano :
    Virus infections under the radar – an NGS analysis
    2022
  • Javier Sanchez Romano :
    Identifying pathogenic virus infections in semi-domesticated reindeer: Virus infections under the radar – PCR and NGS
    2022
  • Anett Kristin Larsen, Javier Sanchez Romano, Eirik Abrahamsen Lænsman, Anne Lotte Vada Hatlegjerde, Jaione Simon-Santamaria, Kim Erlend Mortensen m.fl.:
    Liver sinusoidal scavenger cells eliminate betaherpesvirus from the blood stream
    2022
  • Javier Sanchez Romano, Anett Kristin Larsen, Jaione Simon-Santamaria, Cristina Ionica Øie, Bård Smedsrød, Peter Anthony McCourt m.fl.:
    The role of scavenger endothelial cells in bacteriophage pharmacokinetics
    2022
  • Javier Sanchez Romano, Anett Kristin Larsen, Jaione Simon-Santamaria, Cristina Ionica Øie, Bård Smedsrød, Peter Anthony McCourt m.fl.:
    The role of scavenger endothelial cells in bacteriophage pharmacokinetics
    2022
  • Anett Kristin Larsen, Javier Sanchez Romano, Jaione Simon-Santamaria, Kim Erlend Mortensen, Bo Gøran Ericzon, Peter Anthony McCourt m.fl.:
    Role of liver sinusoidal endothelial cells in elimination of virus
    2022
  • Ingelin Kyrrestad, Javier Sanchez Romano, Anett Kristin Larsen, Ruomei Li, Jaione Simon-Santamaria, Kenneth Bowitz Larsen m.fl.:
    Effect of dynamin inhibitor dynasore on primary mouse liver sinusoidal endothelial cells (LSEC)
    2022
  • Morten Tryland, Birgitta Åhman, Javier Sanchez Romano :
    Health and diseases of semi-domesticated reindeer in a climate change perspective
    Routledge 2022 ARKIV / FULLTEKST / DOI
  • Ann Albihn, Anna Omazic, Åsa Hagström, Morten Tryland, Juha Kantanen, Javier Sanchez Romano m.fl.:
    Virome in Eurasian tundra reindeer (Rangifer t. tarandus) in Norway, Sweden, Finland and Russia – Evidence from Next-Generation-Sequencing (NGS)
    2021
  • Ulrika Rockström, Ann Albihn, Morten Tryland, Javier Sanchez Romano, Erik Ågren, Camilla Risvoll m.fl.:
    Climate change will increase the risk for infectious diseases in the mouth and eyes of reindeer in the Nordic countries
    2021
  • Javier Sanchez Romano, Caroline Aurosell, Valery Fedorov, Åsa Hagström, Juha Kantanen, Mikael Leijon m.fl.:
    Seroprevalence of pestivirus – a potential viral health threat to semi-domesticated and wild reindeer in the Nordic countries and Russia
    2021
  • Javier Sanchez Romano, Anett Kristin Larsen, kjetil helge Elvevold, Christopher Florian Holte, Jaione Simon-Santamaria, Hans H. Hirsch m.fl.:
    SECVIR - The role of scavenger endothelial cells in elimination of virus
    2019
  • Javier Sanchez Romano, Morten Tryland, Ingebjørg Helena Nymo, Anett Kristin Larsen, Karen Kristine Sørensen :
    Infectious keratoconjunctivitis in reindeer - The role of the reindeer alphaherpesvirus
    UiT Norges arktiske universitet 2019
  • Javier Sanchez Romano, Karen Kristine Sørensen, Ingebjørg Helena Nymo, Torill Mørk, Morten Tryland :
    Histopathological study of eye tissues from semi-domesticated reindeer with infectious keratoconjunctivitis caused by cervid herpesvirus 2 in an experimental setting
    2018
  • Morten Tryland, Javier Sanchez Romano, Ingebjørg Helena Nymo, Emily Elisabeth Magnuson, Hong Li :
    Serological screening for viral pathogens among semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus) from eight reindeer herding districts in Norway
    2018
  • Javier Sanchez Romano, Torill Mørk, Sauli Laaksonen, Erik Ågren, Ingebjørg Helena Nymo, Marianne Sunde m.fl.:
    Infectious keratoconjunctivitis in semidomesticated reindeer
    2017
  • Javier Sanchez Romano, Morten Tryland, John A. Angelos, Torill Mørk, Ingebjørg Helena Nymo, Karen Kristine Sørensen :
    The pathogenic role of Moraxella bovoculi in infectious keratoconjunctivitis in semi-domesticated reindeer
    2017
  • Torill Mørk, Berit Marie Blomstrand, Ingebjørg Helena Nymo, Javier Sanchez Romano, Britt Gjerset, Morten Tryland :
    A case of sheep-associated Malignant catarrhal fever in domestic reindeer (Rangifer tarandus tarandus)
    2017
  • Javier Sanchez Romano, Morten Tryland, Ingebjørg Helena Nymo, Torill Mørk, Terje D. Josefsen, Karen Kristine Sørensen :
    Severe transmissible eye infection in reindeer: bacterium or virus?
    2015
  • Morten Tryland, Javier Sanchez Romano, Nina Marcin, P Kiær, OC Kjenstad, Torill Mørk m.fl.:
    Reindeer alphaherpesvirus (CvHV2) and not Moraxella bovoculi caused infectious keratoconjunctivitis experimentally in semi-domesticated reindeer (Rangifer tarandus tarandus)
    2015
  • Morten Tryland, Javier Sanchez Romano, Nina Marcin, Karen Kristine Sørensen, Ingebjørg Helena Nymo, Terje D. Josefsen m.fl.:
    The cause of infectious keratoconjunctivitis in semi-domesticated reindeer - an experimental approach
    2015
  • Javier Sanchez Romano, Nina Marcin, Tone Lille-Mæhlum, Carlos G Das Neves, Sauli Laaksonen, Erik Olof Ågren m.fl.:
    Infectious keratoconjunctivitis in reindeer and the role of Cervid Herpesvirus 2
    2014

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    Forskningsinteresser

    Javier's main research interests are infection biology and virology. He has a collaborative scientific background focused on infection biology (human and nonhuman) in the circumpolar north, but he is also interested in education and the necessity of a holistic approach to health and the development of the One Health concept in the Arctic. 

    His involvement in the SECVIR project is helping him to develop his skills further, including infection biology, virus propagation and purification, molecular biology or advance microscopy. 


    Medlem i forskningsgruppe