Bilde av Øvervatn, Aud Karin
Bilde av Øvervatn, Aud Karin
Overingeniør Autophagy Research Group aud.overvatn@uit.no +4777644725 Her finner du meg

Aud Karin Øvervatn


Stillingsbeskrivelse

Autofagi
Cellesignalering


  • Katrine Stange Overå, Juncal Garcia Garcia, Zambarlal Bhujabal, Ashish Jain, Aud Karin Øvervatn, Kenneth Bowitz Larsen m.fl.:
    TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1
    Journal of Cell Science 02. desember 2019 ARKIV / DOI
  • Gry Hoem, Kenneth Bowitz Larsen, Aud Karin Øvervatn, Andreas Brech, Trond Lamark, Eva Sjøttem m.fl.:
    The FMRpolyGlycine protein mediates aggregate formation and toxicity independent of the CGG mRNA hairpin in a cellular model for FXTAS
    Frontiers in Genetics 2019 ARKIV / DOI
  • Zambarlal Bhujabal, Åsa birna Birgisdottir, Eva Sjøttem, Hanne Britt Brenne, Aud Karin Øvervatn, Sabrina Habisov m.fl.:
    FKBP8 recruits LC3A to mediate Parkin-independent mitophagy
    EMBO Reports 05. april 2017 DOI
  • Hallvard Lauritz Olsvik, Trond Lamark, Kenji Takagi, Kenneth Bowitz Larsen, gry Evjen, Aud Karin Øvervatn m.fl.:
    FYCO1 contains a C-terminally extended, LC3A/B-preferring LC3-interacting region (LIR) motif required for efficient maturation of autophagosomes during basal autophagy
    Journal of Biological Chemistry 2015 ARKIV / DOI
  • Endalkachew Ashenafi Alemu, Trond Lamark, Knut Martin Torgersen, Åsa birna Birgisdottir, Kenneth Bowitz Larsen, Ashish Jain m.fl.:
    ATG8 Family Proteins Act as Scaffolds for Assembly of the ULK Complex SEQUENCE REQUIREMENTS FOR LC3-INTERACTING REGION (LIR) MOTIFS
    Journal of Biological Chemistry 2012 ARKIV / DOI
  • Kenneth Bowitz Larsen, Trond Lamark, Aud Karin Øvervatn, Ingvill Harneshaug, Terje Johansen, Geir Bjørkøy :
    A reporter cell system to monitor autophagy based on p62/SQSTM1
    Autophagy 2010
  • Ashish Jain, Trond Lamark, Eva Sjøttem, Kenneth Bowitz Larsen, Jane Atesoh Awuh, Aud Karin Øvervatn m.fl.:
    p62/SQSTM1 Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription
    Journal of Biological Chemistry 2010 DOI
  • Serliy Pankiv, Endalkachew Alemu, Andreas Brech, Jack-Ansgar Bruun, Trond Lamark, Aud Karin Øvervatn m.fl.:
    FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
    Journal of Cell Biology 2010 DOI
  • Serliy Pankiv, Trond Lamark, Jack-Ansgar Bruun, Aud Karin Øvervatn, Geir Bjørkøy, Terje Johansen :
    Nucleocytoplasmic Shuttling of p62/SQSTM1 and Its Role in Recruitment of Nuclear Polyubiquitinated Proteins to Promyelocytic Leukemia Bodies
    Journal of Biological Chemistry 2010 DOI
  • Terje Clausen, Trond Lamark, Pauline Isakson, Kim Finley, Kenneth Bowitz Larsen, Andreas Brech m.fl.:
    p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
    Autophagy 2010 DOI
  • Geir Bjørkøy, Trond Lamark, Serliy Pankiv, Aud Karin Øvervatn, Andreas Brech, Terje Johansen :
    MONITORING AUTOPHAGIC DEGRADATION OF P62/SQSTM1
    Methods in Enzymology 2009 DOI
  • Vladimir Kirkin, Trond Lamark, Yu-Shin Sou, Geir Bjørkøy, Jennifer Ann Lillebo Nunn, Jack-Ansgar Bruun m.fl.:
    A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates
    Molecular Cell 2009 DOI
  • Serliy Pankiv, Terje Clausen, Trond Lamark, A Brech, Jack-Ansgar Bruun, heidi Outzen m.fl.:
    p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    Journal of Biological Chemistry 2007 FULLTEKST / DOI
  • G Bjørkøy, T Lamark, Andreas Brech, H Outzen, M Perander, A Øvervatn m.fl.:
    p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    Journal of Cell Biology 2005
  • Geir Bjørkøy, Trond Lamark, A Brech, heidi Outzen, maria Perander, Aud Øvervatn m.fl.:
    p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    Journal of Cell Biology 2005
  • Trond Lamark, maria Perander, Heidi Outzen, kurt Kristiansen, Aud Karin Øvervatn, Espen Michaelsen m.fl.:
    Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.
    Journal of Biological Chemistry 2003 FULLTEKST / DOI
  • Geir Bjørkøy, Trond Lamark, Serliy Pankiv, A Brech, heidi Outzen, Aud Øvervatn m.fl.:
    p62 as a direct link between protein aggregates and the autophgic machinery
    2006
  • Geir Bjørkøy, Trond Lamark, Serliy Pankiv, A Brech, heidi Outzen, maria Perander m.fl.:
    P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3
    2006
  • Geir Bjørkøy, Trond Lamark, Serliy Pankiv, A Brech, heidi Outzen, maria Perander m.fl.:
    P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3
    2006
  • Geir Bjørkøy, Trond Lamark, Serliy Pankiv, A Brech, heidi Outzen, maria Perander m.fl.:
    P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3
    2006

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