Bilde av Gabrielsen, Mari
Bilde av Gabrielsen, Mari
Molekylær farmakologi og toksikologi mari.gabrielsen@uit.no +4777644877 Her finner du meg

Mari Gabrielsen


Førsteamanuensis

Vitenskapelige arbeidsområder


  • Ingebrigt Sylte, Mari Gabrielsen, kurt Kristiansen :
    Homology Modeling of Transporter Proteins
    Methods in molecular biology 2023 ARKIV / DOI
  • Linn Evenseth, Riccardo Ocello, Mari Gabrielsen, Matteo Masetti, Maurizio Recanatini, Ingebrigt Sylte m.fl.:
    Exploring Conformational Dynamics of the Extracellular Venus flytrap Domain of the GABA B Receptor: A Path-Metadynamics Study
    Journal of Chemical Information and Modeling 2020 ARKIV / DOI
  • Linn Evenseth, Mari Gabrielsen, Ingebrigt Sylte :
    The GABAB Receptor—Structure, Ligand Binding and Drug Development
    Molecules 2020 ARKIV / DOI
  • Linn Evenseth, Dawid Warszycki, Andrzej J Bojarski, Mari Gabrielsen, Ingebrigt Sylte :
    In Silico Methods for the Discovery of Orthosteric GABAB Receptor Compounds
    Molecules 2019 ARKIV / DOI
  • Thibaud Freyd, Dawid Warszycki, Stefan Mordalski, Andrzej J Bojarski, Ingebrigt Sylte, Mari Gabrielsen :
    Ligand-guided homology modelling of the GABA<sub>B2</sub> subunit of the GABA<sub>B</sub> receptor
    PLOS ONE 2017 ARKIV / DOI
  • Elvar Örn Viktorsson, Mari Gabrielsen, Nugalya Kumarachandran, Ingebrigt Sylte, Pål Rongved, Ove Alexander Høgmoen Åstrand m.fl.:
    Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations
    Steroids 2017 DOI
  • Ove Alexander Høgmoen Åstrand, Elvar Örn Viktorsson, Aleksander Lim Kristensen, Dag Ekeberg, Hanne Røberg-Larsen, Steven Ray Haakon Wilson m.fl.:
    Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors
    Journal of Steroid Biochemistry and Molecular Biology 2017 ARKIV / DOI
  • Irina Kufareva, Vsevolod Katritch, Thibaud Freyd, Mari Gabrielsen, kurt Kristiansen, Ingebrigt Sylte m.fl.:
    Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: Meeting new challenges
    Structure 2014 DOI
  • Mari Gabrielsen, Rafal Kurczab, Agata Siwek, Malgorzata Wolak, Aina Westrheim Ravna, kurt Kristiansen m.fl.:
    Identification of novel serotonin transporter compounds by virtual Screening
    Journal of Chemical Information and Modeling 2014 ARKIV / DOI
  • Mari Gabrielsen, Karol Wolosewicz, Anna Zawadzka, Jerzy Kossakowski, Gabriel Nowak, Malgorzata Wolak m.fl.:
    Synthesis, Antidepressant Evaluation and Docking Studies of Long-Chain Alkylnitroquipazines as Serotonin Transporter Inhibitors
    Chemical Biology and Drug Design (CB&DD) 2013 DOI
  • Yan Baglo, Mari Gabrielsen, Ingebrigt Sylte, Odrun Arna Gederaas :
    Homology Modeling of Human -Butyric Acid Transporters and the Binding of Pro-drugs 5-Aminolevulinic Acid and Methyl Aminolevulinic Acid used in Photodynamic Therapy
    PLOS ONE 2013 ARKIV / DOI
  • Mari Gabrielsen, Rafal Kurczab, aina westrheim Ravna, Irina Kufareva, Ruben Abagyan, Zdzislaw Chilmonczyk m.fl.:
    Molecular mechanism of serotonin transporter inhibition elucidated by a new flexible docking protocol
    European Journal of Medicinal Chemistry 2012 DOI
  • Mari Gabrielsen, aina westrheim Ravna, kurt Kristiansen, Ingebrigt Sylte :
    Substrate binding and translocation of the serotonin transporter studied by docking and molecular dynamics simulations
    Journal of Molecular Modeling 2012 ARKIV / DOI
  • Malgorzata Jaronczyk, Karol Wolosewicz, Mari Gabrielsen, Gabriel Nowak, Irina Kufareva, Aleksander P Mazurek m.fl.:
    Synthesis, in vitro binding studies and docking of long-chain arylpiperazine nitroquipazine analogues, as potential serotonin transporter inhibitors
    European Journal of Medicinal Chemistry 2012 DOI
  • Yan Baglo, Mari Gabrielsen, Ingebrigt Sylte, Odrun Arna Gederaas :
    Homology Modeling of Human -Butyric Acid Transporters and the Binding of Pro-drugs 5-Aminolevulinic Acid and Methyl Aminolevulinic Acid used in Photodynamic Therapy
    2013
  • Mari Gabrielsen :
    Structure, function and inhibition of the serotonin transporter studied by molecular docking, -dynamics and virtual screening
    UiT Norges arktiske universitet 2011
  • Mari Gabrielsen, Ingebrigt Sylte, Svein G. Dahl, aina westrheim Ravna :
    A short update on the structure of drug binding sites on neurotransmitter transporters
    BMC Research Notes 2011 DOI
  • Mari Gabrielsen :
    Docking of substrates and inhibitors into the substrate binding site of two serotonin transporter models
    2011
  • Mari Gabrielsen :
    The search for new SERT inhibitors, possible antidepressant drugs
    2011

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