spring 2019

MBI-3003 Toxicology - 10 ECTS

Sist endret: 12.09.2019

The course is provided by

Faculty of Health Sciences


Tromsø |

Application deadline

Applicants from Nordic countries: 1st of December.

Type of course

Students following the master programme in biomedicine, or other students interested in the topic such as singular course students.

Admission requirements

A bachelor degree in biomedicine or an equivalent bachelor degree.

There is a minimum limit of 3 students for this course. Should there be fewer that 3 students, the course will not run. 

Recommended prerequisites are MBI-2001 Biochemistry, BIO-2305 General animal physiology and MBI-2005 General pharmacology and toxicology.

The minimum average grade requirement is:

  • C - for bachelor's degree or equivalent issued in Europe, Canada, USA, Australia and New Zealand
  • B - for bachelor's degree or equivalent issued in all other countries

Applicationcode to singular course (nordic applicants): 9371

Course content

The following topics are included:

exposure to potentially toxic substances, adverse effects, chemical interactions, epidemiology and human toxicology, toxicodynamics and toxicokinetics, risk assessment and risk management, exposure and monitoring, genetic toxicology, reproductive toxicology, imunotoxicology, skin toxicology, respiratory toxicology, hepato-, nephro- and neuro-toxicity, occupational toxicology, biocides and pesticides.

Recommended prerequisites

BIO-2305 General animal physiology, MBI-2001 Biochemistry, MBI-2005 General pharmacology and toxicology

Objectives of the course

Students should be able to

· explain how toxic substances are handled by an organism (toxicokinetics) and how they affect the organism (toxicodynamics).

· describe the nature of various toxic compounds as well as toxic effects, including their biochemical and molecular mechanisms of action

· explain the dose-response relationships and time-response relationships

Language of instruction


Teaching methods

The course includes lectures (32 hours) and a compulsory semester project. The students must give a mandatory presentation of the semester project to his/her fellow students. The semester project must be approved before the student may attend the exam.


Written exam (4 hours) and alphabetical grades (A-F). The semester project is not a part of the assessment for the alphabetical grade.

Course work requirements: A semester project with an oral presentation of the project must be approved in order to attend the final exam.

A re-sit exam/postponed exam will be arranged early in the following semester, for candidates who failed the exam, or who, for valid reasons, were unable to attend. Previous exams here.

Date for examination

Written test 23.05.2019

The date for the exam can be changed. The final date will be announced in the StudentWeb early in May and early in November.


Course overlap

BIO-262 General and human toxicology 10 stp
MBI-3002 Pharmacology 5 stp

Recommended reading/syllabus

Information about syllabus/reading will be given when the course starts.


Andersen, Anine Therese

Telefon: +4777645363 anine.t.andersen@uit.no

Lisbeth Aasmoe

Førsteamanuensis II