Type of course

Theoretical and practical subject.

The course is available as a singular or elective course independent of study program, also to exchange students and free-movers. The course is offered on condition that a minimum number of students register for the course(minimum every second year).

Admission requirements

Course content

The course is a continuation of KJE-1002 Organic Chemistry and you will do your first steps into the exciting and challenging field of organic synthesis. Several topics known from KJE-1002 like enol chemistry will be treated in more detail. Additionally, a series of new and important types of reactions and their mechanisms will be introduced, e.g. radical reactions, reactions of carbenes, pericyclic reactions and peptide couplings. Important features in the planning of organic syntheses like chemo-, regio- and stereoselectivity and control by protection/deprotection strategies are discussed. In the lab, you will become familiar with general laboratory practice including safety, performance of a range of organic reactions and different separation techniques.

After passing the exam, you as a student will:

Knowledge:

-know a set of important organic transformations

-recognize a standard set of reagents and understand their mode of action

-understand central aspects in the control of organic reactions

-understand the underlying principles for a set of separation techniques

Skills:

-be able to draw the mechanism of important organic reactions

-be able to choose appropriate reagents for the selective transformation of a set of functional groups

-be able to determine the outcome of a reaction and identify possible side reactions

-be able to foresee some experimental requirements for organic transformations based on the mechanism and the reactivity of the reagents

-know were to find information about chemical hazards and how to treat chemicals

-be able to perform organic reactions under different conditions

-be able to isolate and purify organic compounds

General competence:

-recognize reagents and transformations described in the scientific literature

-have gained understanding of how to work and behave in an organic chemistry laboratory

Language of instruction and examination

Teaching methods

Seminars/exercises: 65 h

Laboratory: introduction to laboratory techniques and two literature syntheses; (the laboratory will be open for three weeks)

Assessment

The overall course grade is based on a written 4-hour final exam. Lettergrades (A-F).

Theoretical exercises, a literature analysis and a special topic presentation are work requirements to be completed before the candidate can take the written exam.

Candidates who receive an F (fail) can sign up for the exam again next semester. However, it is recommended to re-take the entire course.

Recommended reading/syllabus

Hand-outs/lecture notes will be provided via Fronter.

Suggested bibliography:

Anslyn, E. og Dougherty, D. A.: Modern Physical Organic Chemistry, 2006

University Science Books, ISBN 1-891389-31-9