RNA and molecular pathology research group (RAMP)
Maria Perander, Kristin Fenton, Zhe Xing

About us

The RNA and molecular pathology (RAMP) research group is studying underlying disease mechanisms in autoimmune disorders and cancer. The group has ongoing studies aimed at increasing the understanding of systemic lupus erythematosus (SLE) and lupus nephritis pathology, the role of RNA/protein nuclear bodies (paraspeckles) and long non-coding RNAs in breast cancer, and the role of endogenous lipid mediators (resolvins) in the transition from acute to chronic inflammation. Extensive efforts are needed to fill the knowledge gaps regarding the complexity of molecular disease mechanisms, diagnostic procedures, and treatment development in chronic inflammatory diseases.

Research projects



Breast cancer-associated long non-coding RNA NEAT1 and paraspeckles in cellular stress responses
Perander, Maria /
Lupus Nephritis-disease mechanisms, detection and therapy
Pedersen, Hege Lynum / Fenton, Kristin Andreassen /
Human Lupus Nephritis
Pedersen, Hege Lynum /
Tissue engineering, organ-on-a-chip and inflammation resolution
Xing, Zhe /

Publications

Link to publications from the RAMP research group.

Members


RNA and molecular pathology research group (RAMP)


Department of Medical Biology (MH-building)

Hansine Hansens veg 74, 9019 Tromsø

hege.lynum.pedersen@uit.no

If interested in bachelor or master projects - read more about our research under "research projects" and/or contact us; Hege Lynum Pedersen, Maria Perander, Kristin Fenton, Zhe Xing

Current PhD students at our group:

Isaac Odonkor: Main supervisor: Maria Perander

Aud Malin Karlsson Hovd. Main supervisor: Hege Lynum Pedersen

Stephanie Rose Nielsen. Main supervisor: Maria Perander

Former PhD students at our group:

2019. "Breast cancer-associated NEAT1 in cellular stress response pathways." Seyed Mohammad Lellahi. Main supervisor: Maria Perander.

2018: "Tertiary Lymphoid Structures (TLS) in Lupus Nephritis. Induction, formation, and detection". Seyey Esmaeil Dorraji. Main supervisor: Kristin Fenton.

2018: "Immunopathology and DNase I in lupus nephritis" Kjersti Daae Horvei. Main supervisor: Hege Lynum Pedersen.

2016: "Comprehensive Analysis of Non-Coding Transcriptomes in Breast Cancer –A Next Generation Sequencing Approach" Erik Knutsen. Main supervisor: Maria Perander.

 
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