Molecular Pharmacology and Toxicology Research Group

About

The Molecular Pharmacology and Toxicology research group uses a combination of experimental and theoretical methods to study molecular mechanism of drugs and toxic substances, and to identify new compounds with a putative therapeutic potential.

Members


Projects



Teaching

Our research group has the responsibility for coordinating teaching in pharmacology and toxicology at all study programmes at the Faculty of Health Sciences except for pharmacy (Kurt Kristiansen). The scientific staff connected to the teaching unit mainly teach basic pharmacology with a focus on the pharmacodynamics and pharmacokinetics of drug groups, but also some clinical pharmacology (medicine year 4 and 6). We also teach basic toxicology in several study programmes at UiT. 


We are responisble for two of the courses in the biomedicine course portfolio:


The scientific staff connected to the Pharmacology and Toxicology teaching unit teach in the following courses (2023): 

Biomedicine - Biomedisin (bachelor and master programmes)


Medicine - Medisin profesjonsstudium


Odontology - Odontologi


Nursing - Sykepleie (full-time and desentralised part-time bachelor programmes)


School nursing/Helsesykepleie (master level programme)


Midwifery - Jordmorfag (master level programme)


Nutrition - Ernæring - bachelor/Klinisk ernæring - master (bachelor and master programmes)


Bioengineering - Bioingeniørfag (bachelor programme)


Publications


Hand eczema and skin complaints in particulate matter-exposed occupations - firefighters, chimney sweepers, and ferrosilicon smelter workers in Norway (Academic article) DOI
Bioaerosol exposure among Norwegian salmon processing workers (Academic lecture)
Eksponering for bioaerosoler og helseeffekter i norsk sjømatindustri (Lecture)

Hall of fame

2010

Anett Kristin Larsen

Proteases from seafood as activators of protease-activated receptor-2 in airway epithelial cells (PhD thesis)


2011

Mari Gabrielsen

Structure, function and inhibition of the serotonin transporter studied by molecular docking, -dynamics and virtual screening (PhD thesis)


Stian Sjøli

Kinetic and docking studies of inhibitors targeting the catalytic zinc in MA clan enzymes (PhD thesis)


2012

Imin Wushur

Structure and fuction of Scaptodrosophila lebanoensis alcohol dehydrogenase (PhD thesis)


2013

Olga Shiryaeva

Respiratory symptoms, lung function, and occupational exposure among seafood industry workers. A study among employees at Norwegian salmon factories and Russian North-West trawl fleet (Arkhangelsk) (PhD thesis)


2014 

Inger Lindin

Mitogen-activated protein kinase-activated protein kinase 5 - Structure, function and inhibition (PhD thesis)


2015

Sampada Satchidanand Bhagwat

Biological exposure agents relevant to the seafood industry work environment as inducers of inflammatory responses in skin and airway cell models (PhD thesis)


2017

Marte Renate Thomassen

Occupational exposure, respiratory health and sensitisation among crab processing workers. A study among processors of king crab (Paralithodes camtschaticus) and edible crab (Cancer pagurus) in Norwegian land based crab processing plants (PhD thesis)


2018 

Thibaud Freyd

Allosteric modulation of GABAergic and glutamatergic metabotropic receptors (PhD thesis)


2019

Linn Samira Mari Evenseth

Ligand binding and dynamics of the GABAB receptor Venus flytrap domain (PhD thesis)


2023 

Fatema Amatur Rahman

Zinc binding and chelating compounds as inhibitors of bacterial metalloproteases and human matrix metalloproteases (PhD thesis)


Molecular Pharmacology and Toxicology Research Group


Professor Ingebrigt Sylte (group leader)
Department of Medical Biology, Faculty of Health Sciences, UiT The Arctic University of Norway, 9037 Tromsø
+4777644705
ingebrigt.sylte@uit.no
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