Sølvi Anderssen. 2000. A study of structure and evolution of the ERV-H family of primate-specific retroviruslike elements. Dr. scient. thesis.

Maria Perander. 2000. Atypical protein kinase C 8: Function in the MEK/ERK signalling pathway and characterization of sequence motifs involved in regulation of subcellular localization.Dr. scient. thesis.

Cecilie Rekdal. 2004. A functional study of the nuclear protein SPBP. Dr. scient. thesis.

Jack-Ansgar Bruun. 2004. Regulation of Pax6 activity by phosphorylation and protein-protein interactions. Dr. scient. thesis

Heidi Outzen. 2005. A search for novel interaction partners for the atypical protein kinase Cs. Dr. scient. thesis

Ernst Ivan Simon Thomassen. 2009. Regulation of the activity of Pax6 by protein-protein interactions mediated by its DNA-binding domains. PhD thesis.

Sylvia Sagen Johnsen. 2009. A functional study of transcriptional co-regulator SPBP. PhD thesis.

Serhiy Pankiv. 2009. p62/SQSTM1 and FYCO1: novel interaction partners of LC3 involved in autophagy. PhD thesis.

Julianne Elvenes. 2011. A study of the transcription factor Pax6: Nuclear mobility and interacting proteins . PhD thesis.

Endalkachew A. Alemu. 2011. A study of novel protein interactions involving atypical protein kinase Cs and ATG8 family proteins. PhD thesis.

Ashish Jain. 2012. Roles of p62 in the Nrf2-Keap1 oxidative stress response pathway in mammals and flies. PhD thesis.

Sagar Darvekar. 2013. A functional study of the chromatin-binding protein SPBP and its homologue RAI1. PhD thesis.

Jennifer Ann Lillebo Nunn. 2014. Functional characterization and regulation of the selective autophagy receptor NBR1. PhD thesis.

Steingrim Svenning. 2014. Evolution and functional analyses of the selective autophagy receptor NBR1. PhD thesis.

Hallvard Lauritz Olsvik. 2016. FYCO1 and NBR1: Autophagy and beyond. PhD thesis.

Mads Skytte Rasmussen. 2017. Roles of LIR-dependent interactions in processing and phosphorylation of ATG8 family proteins. PhD thesis.

Zambarlal Babanrao Bhujabal. 2017. FKBP8 and the autophagy-inducing Class III PI3K Complex. PhD thesis.

Gry Hoem. 2018. Triggering mechanisms in the molecular pathogenesis of FXTAS. PhD thesis.

Yakubu Princely Abudu. 2019. Roles of SAMM50 and NIPSNAP proteins in mitophagy. PhD thesis.

Birendra Kumar Shrestha. 2019. Regulation of Autophagy-related proteins: Roles of post-translational modifications. PhD thesis.

Katrine Stange Overå. 2020. TRIM proteins in autophagy: A study of TRIM32 and TRIM27. PhD thesis.

Thaddaeus Mutugi Nthiga. 2020. Role of CALCOCO1 in scaling down endoplasmic reticulum and Golgi by autophagy. PhD thesis.

Anthimi Palara. 2021. Mechanism and structural requirements for formation of p62 bodies and

degradation of p62 by selective autophagy. PhD thesis.

Juncal Garcia Garcia. 2021. Exploring the roles of TRIM27 and TRIM32 in autophagy. PhD thesis.

Nikoline Lander Rasmussen. 2023. All roads lead to the lysosome: Exploring the degradation of TNIP1 by selective autophagy. PhD thesis.

Completed Master of Science in Biomedicine 1996-2023

Including: Msc in Biomedicine, Msc in Molecular Biotechnology and Msc in Medical Student Research Program 

Eva Sjøttem. 1992. Binding of nuclear proteins to the long terminal repeats of the RTTVL-H family of retrovirus-like elements. Master thesis in MolecularBiotechnology.

Maria Perander. 1993. Heterologous expression in Escherichia coli of the DNA-binding domains of four zebrafish Pax family transcription factors. Master thesis in Molecular Biotechnology.

Gunbjørg Svineng. 1993. A comparative analysis of RTVL-H long terminal repeats from the human chromosome 18. Master thesis in Biomedicine.

Madjid Delghandi. 1994. Functional analyses of one POU family and three Pax family transcription factors from zebrafish. Master thesis in Biomedicine.

Cecilie Andersen. 1995. Functional mapping of the DNA-binding domain of the novel murine transcription factor SPBP. Master thesis in Molecular Biotechnology.

Jack-Ansgar Bruun. 1996. Cloning and functional analyses of a class II POU domain transcription factor from zebrafish. Master thesis in Biomedicine.

Hang Lu, H. 1996. cDNA sequence of the novel murine transcription factor SPBP. Master thesis in Molecular Biotechnology.

Marit Pedersen. 1997. Study of the genomic organization of the Pax6 and Pax10 genes from zebrafish. Master thesis in Molecular Biotechnology.

Odd-Gunnar Wikmark. 1998. Involvement of the zinc finger domain of SPBP in self-interaction revealed via its interaction with a part of the GT1 protein. Master thesis in Molecular Biotechnology.

Stein Ivar Aspmo. 1999. Identification of proteins interacting with the transactivating domain of the transcription factor Pax6. Master thesis in Molecular Biotechnology.

Carlo Gunnar Ossum. 1999. Src-signalling to the human c-myc P1P2 promoter. Master thesis in Biomedicine.

Ernst Ivan Simon Thomassen. 2000. Protein transduction: Delivery of recombinant Tat-PTD fusion proteins into target cells. Master thesis in Biomedicine.

Garth Tylden. 2000. Pax6 and Chx10: A mutational analysis of the interaction between two homeodomain proteins coexpressed during eye morphogenesis. Master thesis in Molecular Biotechnology.

Espen Michaelsen. 2000. Role of the OPR motif in the interaction between the atypical protein kinase C l and the scaffolding protein p62. Master thesis in Molecular Biotechnology.

Silje Reidunn Steinsvik. 2002. Identification of amino acid residues critically involved in forming the interaction surfaces of the PB1 domains of the atypical protein kinase Cs and the scaffolding proteins Par6 and p62. Master thesis in Molecular Biotechnology.

Elisabeth Jarnæss. 2003. Identification of critical amino acids required for the function of the transcriptional activation domain of Stat5a. Master thesis in Molecular Biotechnology.

Julianne Elvenes. 2005. Interactions between the homeodomain and paired domain within and between Pax-family proteins. Master thesis in Molecular Biotechnology.

Rebecca Uglehus Dale. 2005. Proteins interacting with the ePHD domain of SPBP. Master thesis in Molecular Biotechnology.

Endalkachew Ashenafi Alemu. 2005. Identification of novel interaction partners for the atypical protein kinase C lambda/iota. Master thesis in Biomedicine.

Rune Hogseth. 2005. Activation of Pax6 by p38 MAPK isoforms and mutational analyzes of evolutionary cconserved residues in the C-terminus of Pax6. Master thesis in Biomedicine.

Camilla Johanne Sletten. 2006. Self-interaction and polyubiquitin binding by the p62-interacting scaffold protein NBR1. Master thesis in Biomedicine.

Maria Jæger. 2006. Mapping of a nuclear localization signal and a nuclear export signal in the scaffold protein p62/SQSTM1. Master thesis in Molecular Biotechnology.

Ajeagah Divine Usah. 2006. Identification of putative interaction partners of the nuclear protein SPBP. Master thesis in Biomedicine.

Helle Klenow. 2006. A study of the nuclear protein SPBP. Master thesis in Biomedicine.

Agnete Bratsberg Kristiansen. 2007. A study of the nuclear protein SPBP and its interactions with ARID1B, hsRPB7 and chromatin. Master thesis in Molecular Biotechnology.

Jane A. Awuh. 2008. Identification of novel interaction partners for p62/Sequestosome 1 using a candidate approach. Master thesis in Biomedicine.

Eivor Lid Gamst. 2009. A study of the transcriptional co-regulator SPBP as a target for SUMOylation. Master in Molecular Biotechnology.

Terje Høyvarde Clausen. 2009. Master thesis, Medical Student Research Program.

Steingrim Svenning. 2009. Characterization of the Arabidopsis thaliana homologue of NBR1. Master thesis in Biomedicine.

Hallvard Lauritz Olsvik. 2009. Mapping of functional domains in the autophagic cargo receptor NBR1. Master thesis in Molecular Biotechnology.

Hanne Britt Brenne. 2010. Analysis of the p62/SQSTM1 promoter. Master thesis in Molecular Biotechnology.

Cheneso Moumakwa. 2010. Autophagy: investigating the possible interaction between cochaperone BAG3 and the Ubiquitin-binding protein p62. Master thesis in Biomedicine.

Yakubu Princely Abudu. 2013. Studies of the subcellular distribution of human ATG8 family proteins and their role in autophagy. Master thesis in Biomedicine.

Gry Hoem. 2013. Master thesis, Medical Student Research Program

Line Mari Fredriksen. 2015. A study of the autophagy receptor p62/SQSTM1. Impact of ATF4 and 5' untranslated region of mRNA upon amino acid deprivation. Master thesis in Pharmacy.

Betty Martine Normann Furulund. 2016. Identification of protein interaction candidates for the GOLD domain of FYCO1. Master thesis in Biomedicine.

Helene Bekkeli Schäfer. 2016. A study of Fez1 and Fez2: Localization and knock-out. Master thesis in Pharmacy.

Morten Svendsen Næss. 2017. Mapping of Nuclear Export Signals and domains mediating aggregation of NBR1. Master thesis, Medical Student Research Program.

Heidi Isaksen. 2017. Characterization of ATG8 Family Protein Binding to TRIM23 and TRIM31. Master thesis in Biomedicine.

Jenny Thuy Tien Nguyen. 2017. A study of Fez1 and Fez2. Establishment of Fez1 and Fez2 knock out cells lines
Localization of Fez1 and Fez2. Master thesis in Pharmacy.

Apsana Lamsal. 2018. Study of human PRKAR1A and its role in autophagy. Master thesis in Biomedicine.

Arja K. L. A. Løchen. 2020. A study of the mitochondrial dynamics protein OPA1 and its role in mitophagy. Master thesis in Biomedicine.

Nelsy Efundem Taboko. 2020. ATAD3 proteins in autophagy Do ATAD3 proteins have a direct role in regulating autophagy. Master thesis in Biomedicine.

Waqas Khan. 2020. A study of TRIM32 self-ubiquitination. Master thesis in Biomedicine.

Maryam Hosseini. 2021. The PRMT5 and WDR77 components of the Methylosome bind to ATG8 family proteins but are not substrates. Master thesis in Biomedicine.

Kournoutis, A., Lamark, T., Johansen, T. and Abudu, Y.P. 2024. WDR83/MORG1 inhibits RRAG GTPase-MTORC1 signaling to facilitate basal autophagy. Autophagy, 7:1-2. doi: 10.1080/15548627.2024.2322457.

Abudu, Y.P., Kournoutis, A., Brenne, H.B., Lamark, T. and Johansen, T. 2024. MORG1 limits mTORC1 signaling by inhibiting Rag GTPases. Molecular Cell, 84(3):552-569.e11. doi: 10.1016/j.molcel.2023.11.023. Epub 2023 Dec 15.

Nähse, V., Raiborg, C., Tan, K.W., Mørk, S., Torgersen, M.L., Wenzel, E.M., Nager, M., Salo, V.T., Johansen, T., Ikonen, E., Schink, K.O. and Stenmark, H. 2023. ATPase activity of DFCP1 controls selective autophagy. Nature Communications, 14:4051. doi: 10.1038/s41467-023-39641-9.

Rogov, V.V., Nezis, I.P., Tsapras, P., Zhang, H., Dagdas, Y., Noda, N.N., Nkatogawa, H., Wirth, M., Mouilleron, S., McEwan, D.G., Behrends, C., Deretic, V., Elazar, Z., Tooze, S.A., Dikic, I., Lamark, T., and Johansen, T. 2023. Atg8 family proteins, LIR/AIM motifs and other interaction modes. Autophagy Reports 2, 2188523. doi: 0.1080/27694127.2023.2188523.

Rasmussen, N.L., Zhou, J., Olsvik, H., Kaeser-Pebernard, S., Lamark, T., Dengjel, J. and Johansen, T. 2023. The inflammation repressor TNIP1/ABIN is degraded by autophagy following TBK1 phosphorylation of its LIR. Autophagy Mar 9:1-3. doi: 10.1080/15548627.2023.2185013.

Zhou, J., Rasmussen, N.L., Olsvik, H.L., Akimov, V., Hu, Z., Evjen, G., Kaeser-Pebernard, S., Sankar, D.S., Roubaty, C., Verlhac, P., van de Beck, N., Reggiori, F., Abudu, Y.P., Blagoev, B., Lamark, T., Johansen, T. and Dengjel, J. 2023. TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1. J. Cell Biol. 222: e202108144. doi: 10.1083/jcb.202108144. Epub 2022 Dec 27.

McLaren Berge, A.K., Garcia-Garcia, J., Sjøttem, E., and Olsvik, H.L. 2023. The ubiquitin E3 ligase TRIM27 emerges as a new player in mitophagy. Autophagy Reports, 2, 2164089 doi: 10.1080/27694127.2022.2164089. ®

Olsvik, H.L. and Johansen, T. 2023. AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research. PLoS Biol. 21, e3002002. doi: 10.1371/journal.pbio.3002002.

Kournoutis, A.. and Johansen, T. 2023. LC3B is a cofactor for LMX1B-mediated transcription of autophagy genes in dopaminergic neurons. J. Cell Biol. 222, e202303008. doi: 10.1083/jcb.202303008.

Wang, Y., Eapen, V.V., Kournoutis, A., Onorati, A., Li, X., Zhou, X., Cetinbas, M., Wang, L., Liu, J., Bretz, C., Zhou, Z., Sui, S.J.H., Saladi, S.V., Sadreyev, R.I., Adams, P.D., Kingston, R.E., Yue, Z., Johansen, T. and Dou, Z. 2022. Nuclear autophagy interactome unveils WSTF as a constitutive nuclear inhibitor of inflammation. bioRxiv 2022.10.04.510822; doi:10.1101/2022.10.04.510822

Garcia-Garcia, J., Berge, A.K.M., Overå, K.S., Larsen, K.B., Bhujabal, Z., Brech, A., Abudu, Y.P., Lamark, T., Johansen, T. and Sjøttem, E. 2022. TRIM27 is an autophagy substrate facilitating mitochondria clustering and mitophagy via phosphorylated TBK1. FEBS J. 290,1096-1116. doi:10.1111/febs.16628

Jia, J., Wang, F., Bhujabal, Z., Peters, R., Mudd, M., Duque, T., Allers, L., Javed, R., Salemi, M., Behrends, C., Phinney, B., Johansen, T. and Deretic, V. 2022. Membrane Atg8ylation, stress granule formation, and MTOR regulation during lysosomal damage. Autophagy doi: 10.1080/15548627.2022.2148900. Online ahead of print.®

Jia, J., Wang, F., Bhujabal, Z., Peters, R., Mudd, M., Duque, T., Allers, L., Javed, R., Salemi, M., Behrends, C,. Phinney, B., Johansen, T. and Deretic, V. 2022. Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage. J. Cell Biol. 221, e202207091. doi: 10.1083/jcb.202207091

Rasmussen, N.L., Kournoutis, A., Lamark, T. and Johansen, T. 2022. NBR1: The archetypal selective autophagy receptor. J. Cell Biol. 221:e202208092. doi: 10.1083/jcb.202208092. ®

de la Riva Carrasco, R., Perez Pandolfo, S., Freire, S.S., Romero, N.M., Bhujabal, Z., Johansen, T., Wappner, P., and Melani, M. 2021. The immunophilin Zonda controls regulated exocytosis in endocrine and exocrine tissues. Traffic, 22, 111-122

Nthiga, T.M., Shrestha, B.K., S., Lamark, T., and Johansen, T. 2021. The soluble reticulophagy receptor CALCOCO1 is also a Golgiphagy receptor. Autophagy 17, 2051-2052. doi: 10.1080/15548627.2021.1940610. ®

Nthiga, T.M., Shrestha, B.K., S., Bruun, J.-A., Larsen, K.B., Lamark, T., and Johansen, T. 2021. Regulation of Golgi turnover by CALCOCO1-mediated selective autophagy. J. Cell Biol. 220:e202006128. doi: 10.1083/jcb.202006128.

Petridi, S., Jacomin, A-C., Bhujabal, Z., Johansen, T., and Nezis, I. 2021. Exploring selective autophagy in Drosophila: Methods to identify Atg8-interacting proteins. Methods Cell Biol. 165, 13-29. doi: 10.1016/bs.mcb.2020.10.008.

Klionsky, D……..Johansen, T……, And Tong, C.K. 2021. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. ®

Wirth, M., Mouilleron, S., Zhang, W., Sjøttem, E., Abudu, Y.P., Jain, A., Olsvik, H.L., Bruun, J-A., Razi, M., Jefferies, H.B.J., Lee, R., Joshi, D., O'Reilly, N., Johansen, T., and Tooze, S.A. 2021. Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity. J. Mol. Biol. 433, 166987. doi: 10.1016/j.jmb.2021.166987.

Garcia, J.G., Stange Overå, K., Khan, W., and Sjøttem, E. 2021. Generation of the short TRIM32 isoform is regulated by Lys 247 acetylation and a PEST sequence. PLoS One 16, e0251279.  doi: 10.1371/journal.pone.0251279. eCollection 2021.

Abudu, Y.P., Shrestha, B.K., Zhang, W., Palara, A., Brenne, H.B., Larsen, K.B., Wolfson, D.L., Dumitriu, G., Øie, C.I., Ahluwalia, B.S., Levy, G., Behrends, C., Tooze, S.A., Mouilleron, S., Lamark, T. and Johansen, T. 2021. SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components. J. Cell Biol. 220, e202009092. doi: 10.1083/jcb.202009092.

Abudu, Y.P., Mouilleron, S., Tooze, S.A., Lamark, T., and Johansen, T. 2021. SAMM50 is a receptor for basal piecemeal mitophagy and acts with SQSTM1/p62 in OXPHOS-induced mitophagy.  Autophagy 17, 2656-2658. doi: 10.1080/15548627.2021.1953846.

Lamark, T., and Johansen, T. 2021. Mechanisms of Selective Autophagy. Ann. Rev. Cell Dev. Biol. 37, 143-169. doi: 10.1146/annurev-cellbio-120219-035530.

Claude-Taupin, A., Jia, J., Bhujabal, Z., Garfa-Traoré, M., Kumar, S., da Silva, G.P.D., Javed, R., Gu, Y., Allers, L., Peters, R., Wang, F., da Costa, L.J., Pallikkuth, S., Lidke, K.A., Mauthe, M., Verlhac, P., Uchiyama, Y., Salemi, M., Phinney, B., Tooze, S.A., Mari, M.C., Johansen, T., Reggiori, F., and Deretic, V. 2021. ATG9A protects the plasma membrane from programmed and incidental permeabilization. Nat. Cell Biol. 23, 846-858. doi: 10.1038/s41556-021-00706-w.

Aman, Y., Schmauck-Medina, T., Hansen, M., Morimoto, R.I., Simon, A.K., Bjedov, I., Palikaras, K. Simonsen, A., Johansen, T., Tavernarakis, N., Rubinsztein, D.C., Partridge, L., Kroemer, G., Labbadia, J. and Fang, E.F. 2021. Autophagy in healthy aging and disease. Nat. Aging, 1, 634–650. Doi: 10.1038/s43587-021-00098-4 ®

Klionsky, D.J., Petroni, G., Amaravadi, R.K., Baehrecke, E.H., Ballabio, A., Boya, P., Bravo-San Pedro, J.M., Cadwell, K., Cecconi, F., Choi, A.M.K., Choi, M.E., Chu, C.T., Codogno, P., Colombo, M.I., Cuervo, A.M., Deretic, V., Dikic, I., Elazar, Z., Eskelinen, E-L., Fimia, G.M., Gewirtz, D.A., Green, D.R., Hansen, M., Jäättelä, M., Johansen, T., Juhász, G., Karantza, V., Kraft, C., Kroemer, G., Ktistakis, N.T., Kumar,S., Lopez-Otin, C., Macleod, K.F., Madeo, F., Martinez, J.F., Meléndez, A., Mizushima, N., Münz, C., Penninger, J.M., Perera, R.M., Piacentini, M., Reggiori, F., Rubinsztein, D.C., Ryan, K.M., Sadoshima, J., Santambrogio, L., Scorrano, L., Simon, H-U., Simon, A.K., Simonsen, A., Stolz, A., Tavernarakis, N., Tooze, S.A., Yoshimori, T., Yuan, J., Yue, Z., Zhong, Q., Galluzzi, L., and Pietrocola, F. 2021. Autophagy in major human diseases. EMBO J. 40, e108863 doi: 10.15252/embj.2021108863 ®

Johansen, T., and Lamark, T. 2020. Selective Autophagy: ATG8 Family Proteins, LIR Motifs and Cargo Receptors. J. Mol. Biol. 432, 80-103.®

Shrestha, B.K., Skytte Rasmussen M., Abudu, Y.P., Bruun, J-A., Larsen, K.B., Alemu, E.A., Sjøttem, E., Lamark, T., and Johansen, T. 2020. NIMA-related kinase 9-mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1. J Biol Chem. 295, 1240-1260.

Jakobi, A.J., Huber, S.T., Mortensen, S.A., Schultz, S.W., Palara, A., Kuhm, T., Shrestha, B.K., Lamark, T., Hagen, W.J.H., Wilmanns, M., Johansen, T., Brech, A., and Sachse, C. 2020. Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake. Nature Commun. 11(1):440. doi: 10.1038/s41467-020-14343-8.

Mercado, N., Colley, T., Baker, J.R., Vuppussetty, C., Kono, Y., Clarke, C., Tooze, S., Johansen, T., and Barnes, P.J. 2020. Bicaudal D1 impairs autophagosome maturation in chronic obstructive pulmonary disease. FASEB Bioadv. 1, 688-705.

Jacomin, A.C., Petridi, S., Di Monaco, M., Bhujabal, Z., Jain, A., Mulakkal, N.C., Palara, A., Powell, E.L., Chung, B., Zampronio, C., Jones, A., Cameron, A., Johansen, T., and Nezis, I.P. 2020. Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila. Cell Rep. 31(8):107695. doi: 10.1016/j.celrep.2020.107695.

Birgisdottir, Å.B, and Johansen, T. 2020. Autophagy and endocytosis - interconnections and interdependencies. J. Cell Sci. 133(10):jcs228114. doi: 10.1242/jcs.228114. ®

Nthiga, T.M., Shrestha, B.K., Sjøttem, E., Bruun, J-A., Bowitz Larsen, K., Bhujabal, Z., Lamark, T., and Johansen, T. 2020. CALCOCO1 acts with VAMP-associated proteins to mediate ER-phagy. EMBO J. 39(15):e103649. doi: 10.15252/embj.2019103649.

Nthiga, T.M., Shrestha, B.K., S., Lamark, T., and Johansen, T. 2020. CALCOCO1 is a soluble reticulophagy receptor. Autophagy 16, 1729-1731. doi: 10.1080/15548627.2020.1797289. Online ahead of print. ®

Xu, C., Wang, L., Fozouni, P., Evjen, G., Chandra, V., Jiang, J., Lu, C., Nicastri, M., Bretz, C., Winkler, J.D., Amaravadi, R., Garcia, B.A., Adams, P.D., Ott, M., Tong, W., Johansen, T., Dou, Z., and Berger, S.L. 2020. SIRT1 is downregulated by autophagy in senescence and ageing. Nature Cell Biol. 22, 1170-1179. doi: 10.1038/s41556-020-00579-5

Jacomin., A.C., Gohel, R., Hussain, Z., Varga, A., Maruzs, T., Eddison, M., Sica, M., Jain, A., Moffat, K.G., Johansen, T., Jenny, A., Juhasz, G., and Nezis, I.P. 2020. Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila. Life Sci. Alliance, e202000965. doi: 10.26508/lsa.202000965.

Wang, L., Xu, C., Johansen, T., Berger, S.L., and Dou, Z. 2020. SIRT1 - a new mammalian substrate of nuclear autophagy. Autophagy 17, 593-595. doi: 10.1080/15548627.2020.1860541 ®

Jia J., Abudu, Y.P., Claude-Taupin, A., Gu, Y., Kumar, S., Choi, S.W., Peters, R., Mudd, M.H., Allers, L., Salemi, M., Phinney, B., Johansen, T., and Deretic, V. 2019. Galectins control MTOR and AMPK in response to lysosomal damage to induce autophagy. Autophagy 15, 169-171.

Olsvik, H.L., Svenning, S., Abudu, Y.P., Brech, A., Stenmark, H., Johansen, T., and Mejlvang, J. 2019. Endosomal microautophagy is an integrated part of the autophagic response to amino acid starvation. Autophagy 15, 182-183. ®

Rasmussen, M.S., Birgisdottir, Å.B., and Johansen, T. 2019. Use of Peptide Arrays for Identification and Characterization of LIR Motifs. Methods Mol. Biol.  1880, 149-161.

Birgisdottir, Å.B., Mouilleron, S., Bhujabal, Z., Wirth, M., Sjøttem, E., Evjen, G., Zhang, W., Lee, R., O'Reilly, N., Tooze, S.A., Lamark, T., and Johansen, T. 2019. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy 15, 1333-1355.

Kumar, S., Gu, Y., Abudu, Y.P., Bruun, J.-A., Jain, A., Farzam, F., Mudd, M., Anonsen, J.H., Rusten, T.E., Kasof, G., Ktistakis, N., Lidke, K.A., Johansen, T., and Deretic, V. 2019. Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation. Dev. Cell 49, 130-144. e6. doi: 10.1016/j.devcel.2019.01.027.

Princely Abudu, Y., Pankiv, S., Mathai, B.J., Lystad, A. H., Bindesbøll, C., Brenne, H.B., Yoke, Wui Ng M., Thiede, B., Yamamoto, A., Mutugi Nthiga, T., Lamark, T., Esguerra, C.V., Johansen, T., and Simonsen, A. 2019. NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy. Dev. Cell 49, 509-525.e12. doi: 10.1016/j.devcel.2019.03.013.

Hoem, G., Bowitz Larsen, K., Øvervatn, A., Brech, A., Lamark, T., Sjøttem, E., and Johansen, T. 2019. The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS. Front. Genet. 10, 249. doi: 10.3389/fgene.2019.00249. eCollection 2019.

Johansen, T. 2019. Selective Autophagy: RNA Comes from the Vault to Regulate p62/SQSTM1. Curr. Biol. 29(8):R297-R299. doi: 10.1016/j.cub.2019.03.008. ®

Wirth, M., Zhang, W., Razi, M., Nyoni, L., Joshi, D., O'Reilly, N., Johansen, T., Tooze, S.A., and Mouilleron, S.V. 2019. Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins. Nat. Commun. 10(1):2055. doi: 10.1038/s41467-019-10059-6.

Abudu, Y.P., Pankiv, S., Mathai, B.J., Lamark, T., Johansen, T. and Simonsen, A. 2019. NIPSNAP1 and NIPSNAP2 act as "eat me" signals to allow sustained recruitment of autophagy receptors during mitophagy. Autophagy 15, 1845-1847. ®

Kehl, S.R., Soos, B.A., Saha, B., Choi, S.W., Herren, A.W., Johansen, T., and Mandell, M.A. 2019. TAK1 converts Sequestosome 1/p62 from an autophagy receptor to a signaling platform. EMBO Rep. Sep;20(9):e46238. doi: 10.15252/embr.201846238.

Pölönen, P., Jawahar Deen, A., Leinonen, H.M., Jyrkkänen, H.K., Kuosmanen, S., Mononen, M., Jain, A., Tuomainen, T., Pasonen-Seppänen, S., Hartikainen, J.M., Mannermaa, A., Nykter, M., Tavi, P., Johansen, T., Heinäniemi, M., and Levonen, A.L. 2019. Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma. Oncogene 38, 7473-7490.

Gu, Y., Princely Abudu, Y., Kumar, S., Bissa, B., Choi, S.W., Jia, J., Lazarou, M., Eskelinen, E.L., Johansen, T. and Deretic, V. 2019. Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs. EMBO J. 38:e101994. doi: 10.15252/embj.2019101994.

Overå, K. S., Garcia-Garcia, J., Bhujabal, Z., Jain, A., Øvervatn, A., Larsen, K.B., Deretic, V., Johansen, T., Lamark, T., and Sjøttem, E. 2019. TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1. J Cell Sci. 132(23): jcs236596. doi: 10.1242/jcs.236596.

Schwob, A., Teruel, E., Dubuisson, L., Lormières. F., Verlhac, P., Abudu, Y.P., Gauthier, J., Naoumenko, M., Cloarec-Ung, F.M., Faure, M., Johansen, T., Dutartre, H., Mahieux, R., and Journo, C. 2019. SQSTM-1/p62 potentiates HTLV-1 Tax-mediated NF-κB activation through its ubiquitin binding function. Sci. Rep. 9(1):16014. doi: 10.1038/s41598-019-52408-x.

Hafrén, A., Üstün, S., Hochmuth, A., Svenning, S., Johansen, T., and Hofius, D. 2018. Turnip mosaic virus counteracts selective autophagy of the viral silencing suppressor HCpro. Plant Physiol., 176, 649–662

Fusco, C., Mandriani, B., Di Rienzo, M., Micale, L., Malerba, N., Cocciadiferro, D., Sjøttem, E., Augello, B., Squeo, G.M., Pellico, M.T., Jain, A., Johansen, T., Fimia, G.M., Merla, G. 2018. TRIM50 regulates Beclin 1 proautophagic activity. Biochim. Biophys. Acta, 1865, 908-919

Jia, J., Abudu, Y.P., Claude-Taupin, A., Gu, Y., Kumar, S., Choi, S.W., Peters, R., Mudd, M.H., Allers, L., Salemi, M., Phinney, B., Johansen, T., and Deretic, V. 2018. Galectins Control mTOR in Response to Endomembrane Damage. Mol. Cell, 70, 120-135

Mejlvang, J., Olsvik, H., Svenning, S., Bruun, J.-A., Abudu, Y.P., Bowitz Larsen, K., Brech, A., Hansen, T.E., Brenne, H., Hansen, T., Stenmark, H., and Johansen, T. 2018. Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy. Journal of Cell Biology, 217, 3640-3655

Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Sklar LA, Allers L, Garcia SA, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, Eskelinen EL, Fourie B, Gozuacik D, Hong W, Hotamisligi G, Jäättelä M, Jo EK, Johansen T, Juhász G, Kimchi A, Ktistakis N, Kroemer G, MIzushima N, Münz C, Reggiori F, Rubinsztein D, Ryan K, Schroder K, Simonsen A, Tooze S, Vaccaro MI, Yoshimori T, Yu L, Zhang H, Klionsky DJ. 2018. Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations. Autophagy 14, 925-929. ®

Katheder, N.S., Khezri, R., O’Farrell, F., Schultz, S.W., Jain, A., Rahman, M.M., Schink, K.O., Theodossiou, T.A., Johansen, T., Juhász, G., Bilder, D., Brech, A., Stenmark, H. and Rusten, T.E. 2017. Microenvironmental autophagy promotes tumour growth. Nature, 541, 417-420

Skytte Rasmussen, M., Mouilleron, S., Kumar Shrestha, B., Wirth, M., Lee, R., Bowitz Larsen, K., Abudu Princely, Y., O`Reilly, N., Sjøttem, E., Tooze, S.A., Lamark, T. and Johansen, T. 2017. ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of ATG8 family proteins. Autophagy, 13, 834-853 

Johansen, T., Birgisdottir, Å.B., Huber, J., Kniss, A., Dötsch, V., Kirkin, V. and Rogov, V.V. 2017. Methods for Studying Interactions Between Atg8/LC3/GABARAP and LIR-Containing Proteins. Methods of Enzymol. 587, 143-169

Abreu, S., Kriegenburg, F., Gómez-Sánchez, R., Mari, M., Sánchez-Wandelmer, J.,Skytte Rasmussen, M., Soares Guimarães, R., Zens, B., Schuschnig, M., Hardenberg, R., Peter, M., Johansen, T., Kraft, C., Martens, S. and Reggiori, F. 2017. Conserved Atg8 recognition sites mediate Atg4 association with autophagosomal membranes and Atg8 deconjugation. EMBO Reports, 18, 765-780

Kimura, T., Jain, A., Choi, S.W., Mandell, M.A., Johansen, T. and Deretic, V. 2017. TRIM-directed selective autophagy regulates immune activation. Autophagy, 13, 989-990

Kimura, T., Jia, J., Claude-Taupin, A., Kumar, S., Choi, S.W., Gu, Y., Mudd, M., Dupont, N., Jiang, S., Peters, R., Farzam, F., Jain, A., Lidke, K.A., Adams, C.M., Johansen, T. and Deretic, V. 2017. Cellular and molecular mechanism for secretory autophagy. Autophagy, 13, 1084-1085

Kumar, S., Chauhan, S., Jain, A., Ponpuak, M., Choi, S.W., Mudd, M., Peters, R., Mandell, M.A., Johansen, T., and Deretic, V. 2017. Galectins and TRIMs directly interact and orchestrate autophagic response to endomembrane damage. Autophagy, 13,1086-1087

Bhujabal, Z., Birgisdottir, Å.B., Sjøttem, E., Brenne, H.B., Øvervatn A., Habisov, S., Kirkin, V., Lamark, T. and Johansen, T. 2017. FKBP8 recruits LC3A to mediate Parkin-independent mitophagy. EMBO Reports, 18, 947-961

Galluzzi, L., Baehrecke, E.H., Ballabio, A., Boya, P., Bravo-San Pedro, J.M., Cecconi, F., Choi, A.M., Chu, C.T., Codogno, P., Colombo, M.I., Cuervo, A.M., Debnath, J., Deretic, V., Dikic, I., Eskelinen, E.L., Fimia, G.M., Fulda, S., Gewirtz, D.A., Green, D.R., Hansen, M., Harper, J.W., Jäättelä, M., Johansen, T., Juhasz, G., Kimmelman, A.C., Kraft, C., Ktistakis, N.T., Kumar, S., Levine, B., Lopez-Otin, C., Madeo, F., Martens, S., Martinez, J., Melendez, A., Mizushima, N., Münz, C., Murphy, L.O., Penninger, J.M., Piacentini, M., Reggiori, F., Rubinsztein, D.C., Ryan, K.M., Santambrogio, L., Scorrano, L., Simon, A.K., Simon, H.U., Simonsen, A., Tavernarakis, N., Tooze, S.A., Yoshimori, T., Yuan, J., Yue, Z., Zhong, Q., and Kroemer, G. 2017. Molecular definitions of autophagy and related processes. EMBO J. 36, 1811-1836®

Melani, M., Valko, A., Romero, N.M., Aguilera, M.O., Acevedo, J.M., Bhujabal, Z., Perez-Perri, J., de la Riva-Carrasco, R.V., Katz, M.J., Sorianello, E., D'Alessio, C., Juhász, G., Johansen, T., Colombo, M.I., and Wappner, P. 2017. Zonda is a novel early component of the autophagy pathway in Drosophila. Mol. Biol. Cell, 28, 3070-3081

Tusco, R., Jacomin, A.C., Jain, A., Penman, B.S., Larsen, K.B., Johansen, T., and Nezis,  I.P. 2017. Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses. Nature Commun., 8, 1264. doi:10.1038/s41467-017-01287-9

Lamark, T., Svenning, S., and Johansen, T. 2017. Regulation of selective autophagy: the p62/SQSTM1 paradigm. Essays Biochem., 61, 609-624®

Puvirajesinghe, T.M., Bertucci, F., Jain, A., Scerbo, P., Belotti, E., Audebert, S., Sebbagh, M., Lopez, M., Brech, A., Finetti, P., Charafe-Jauffret, E., Chaffanet, M., Castellano, R., Restouin, A., Marchetto, S., Collette, Y., Gonçalvès, A., Macara, I., Birnbaum, D., Kodjabachian, L., Johansen, T. and Borg, J.P. 2016. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nature Communications 7, 10318. doi: 10.1038/ncomms10318

Klionsky, D.J., …. Johansen, T…….Lamark., T. and xxxx others. 2016. Guidelines for the use and interpretation of assays for monitoring autophagy (3^rd edition). Autophagy 12, 1-222

Kimura, T., Jain, A., Choi, S.W., Mandell, M.A., Johansen, T. and Deretic, V. 2016. TRIM-Directed Selective Autophagy Regulates Immune Activation. Autophagy, 13, 989-990

Habisov, S., Huber, J., Ichimura, Y., Akutsu, M., Rogova, N., Loehr, F., McEwan, D.G., Johansen, T., Dikic, I., Doetsch, V., Komatsu, M., Rogov, V. and Kirkin V. 2016. Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation. J. Biol. Chem. 291, 9025-9041

Goode, A., Butler, K., Long, J., Cavey, J., Scott, D., Shaw, B., Sollenberger, J., Gell, C., Johansen, T., Oldham, N.J., Searle, M.S. and Layfield, R. 2016. Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD. Autophagy, 12, 1094-1104

Hewitt, G., Carroll, B., Sarallah, R., Correia-Melo, C., Ogrodnik, M., Nelson, G., Otten, E.G., Manni, D., Antrobus, R., Morgan, B.A., von Zglinicki, T., Jurk, D., Seluanov, A., Gorbunova, V., Johansen, T., Passos, J.F. and Korolchuk V.I. 2016. SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. Autophagy, 12, 1917-1930

Mandell, M.A., Jain, A., Kumar, S., Castleman, M.J., Anwar, T., Eskelinen, E.L., Johansen, T., Prekeris, R. and Deretic, V. 2016. TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation. J. Cell Sci. 129, 3562-3573

Chauan, S., Kumar, S., Jain, A., Ponpuak, M., Mudd, M.H., Kimura, T., Choi, S.W., Peters, R., Mandell, M., Bruun, J.-A., Johansen, T., and Deretic, V. 2016. TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis. Dev. Cell 39, 13-27

Kimura, T., Jia, J., Kumar, S., Choi, S.W., Gu, Y., Mudd, M., Dupont, N., Jiang, S., Peters, R., Farzam, F., Jain, A., Lidke, K.A., Adams, C.M., Johansen, T. and Deretic, V. 2016. Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy. EMBO J. 36, 42-60

Borel, S., Robert-Hebmann, V., Alfaisal, J., Jain, A., Faure, M, Espert, L., Chaloin, L., Paillart, J.C., Johansen, T. and Biard-Piechaczyk, M. 2015. HIV-1 viral infectivity factor .with light chain 3 and inhibits autophagy. AIDS 29, 275–286

Bertrand M, Petit V, Jain A, Amsellem R, Johansen T, Larue L, Codogno P, Beau I. 2015. SQSTM1/p62 regulates the expression of junctional proteins through epithelial-mesenchymal transition factors. Cell Cycle 14, 364-374

Raiborg, C., Wenzel, E.M., Pedersen, N.M., Olsvik, H., Schink, K.O., Schultz, S.W., Vietri, M., Nisi, V., Bucci, C., Brech, A., Johansen, T. and Stenmark, H. 2015. Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth. Nature 520, 234-238

Bruun, J., Kolberg, M., Ahlquist, T.C., Røyrvik, E., Nome, T., Leithe, E., Lind, G.E., Merok, M.A., Rognum, T.O., Bjørkøy, G., Johansen, T., Lindblom, A., Sun, X.F., Svindland, A., Liestøl, K., Nesbakken, A., Skotheim, R.I. and Lothe, R.A. 2015. Regulator of chromosome condensation 2 identifies high-risk patients within both major phenotypes of colorectal cancer. Clin. Cancer Res. 21, 3759-3770

Ciuffa, R., Lamark, T., Tarafder, A.K., Guesdon, A., Rybina, S., Hagen, W.J., Johansen, T. and Sachse, C. 2015. The Selective Autophagy Receptor p62 Forms a Flexible Filamentous Helical Scaffold. Cell Rep. 11, 748-758

Johansen, T. and Sachse, C. 2015. The higher-order molecual rorganization of p62/SQSTM1. Oncotarget 6, 16796-16797

Jain, A., Rusten, T.E., Katheder, N., Elvenes, J., Bruun, J.A., Sjøttem, E., Lamark, T. and Johansen, T. 2015. p62/sequestosome-1, autophagy-related gene 8 and autophagy in Drosophila are regulated by Nuclear factor erythroid 2-related factor 2 (NRF2), independent of transcription factor TFEB. J. Biol. Chem. 290, 14945-14962

Kimura, T., Jain, A., Choi, S.W., Mandell, M.A., Schroder, K., Johansen, T. and Deretic, V. 2015. TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity. J. Cell Biol. 210, 973-989

Olsvik, H.L., Lamark, T., Takagi, K., Bowitz Larsen, K., Evjen, G., Øvervatn, A., Mizushima, T. and Johansen, T. 2015. FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-Interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes During Basal Autophagy. J. Biol. Chem. 290, 29361-29374

Dou, Z., Xu, C., Donahue, G., Shimi, T., Pan, J.A., Zhu, J., Ivanov, A., Capell, B.C., Drake, A.M., Shah. P.P., Catanzaro, J.M., Daniel Ricketts, M., Lamark, T, Adam, S.A., Marmorstein, R., Zong, W.X., Johansen, T., Goldman, R.D., Adams, P.D. and Berger, S.L. 2015. Autophagy mediates degradation of nuclear lamina. Nature 527, 105-109

Darvekar, S., Elvenes, J., Brenne, H. B., Johansen, T. and Sjøttem, E. 2014. SPBP is a Sulforaphane Induced Transcriptional Coactivator of NRF2 Regulating Expression of the Autophagy Receptor p62/SQSTM1. PLoS One 9,e85262. doi: 10.1371/journal.pone.0085262

Rubio, N., Verrax, J., Dewaele, M., Verfaillie, T., Johansen, T., Piette, J. and Agostinis, P. 2014. p38MAPK-regulated induction of p62 and NBR1 after photodynamic therapy promotes autophagic clearance of ubiquitin aggregates and reduces reactive oxygen species levels by supporting Nrf2–antioxidant signaling. Free Radical Biol. Med. 67, 292-303

Rogov, V., Dötsch, V., Johansen, T. and Kirkin, V. 2014. Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy. Mol. Cell 53,167-178

Kalvari, I., Tsompanis, S., Mulakkal, N.C., Osgood, R., Johansen, T., Nezis, I.P. and Promponas, V.J. 2014.  iLIR: A web resource for prediction of Atg8-family interacting proteins. Autophagy 10, 913-925

Johansen, T. and  Lamark, T. 2014. Selective autophagy goes exclusive. Nat Cell Biol. 16, 395-397

Mandell, M.A., Jain, A., Arko-Mensah, J., Chauhan, S., Kimura, T., Dinkins, C., Silvestri, G., Münch, J., Kirchhoff, F., Simonsen, A., Wei, Y., Levine, B., Johansen, T. and Deretic, V. 2014. TRIM Proteins Regulate Autophagy and Can Target Autophagic Substrates by Direct Recognition. Dev Cell. 30, 394-409

Mandell, M.A., Kimura, T., Jain, A., Johansen, T. and Deretic, V. 2014. TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction. Autophagy 10, 2387-2388

Deosaran E., Larsen, K.B., Hua, R., Sargent, G., Wang, Y., Kim., S., Lamark, T., Jauregui, M., Law, K., Lippincott-Schwartz, J., Brech, A., Johansen, T. and Kim, P.K. 2013. NBR1 acts as an autophagy receptor for peroxisomes. J. Cell Sci. 126, 939-952

Birgisdottir, A. B., Lamark, T. and Johansen, T. 2013. The LIR motif - crucial for selective autophagy. J. Cell Sci.126, 3237-3247

Svenning, S. and Johansen, T. 2013. Selective autophagy. Essays Biochem. 55, 79-92

Darvekar, S., Rekdal, C., Johansen, T. and Sjøttem, E. 2013. A Phylogenetic Study of SPBP and RAI1: Evolutionary Conservation of Chromatin Binding Modules. PLoS One 8,e78907. doi: 10.1371/journal.pone.0078907

Darvekar, S., Johnsen, S.S., Eriksen, A.B., Johansen, T. and Sjøttem, E. 2012. Identification of two independent nucleosome-binding domains in the transcriptional co-activator SPBP. Biochem. J. 442, 65-75

McKnight, N. C., Jeffries, H. B., Alemu, E. A., Saunders, R. E., Howell, M., Johansen, T. and Tooze, S. A. 2012. Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC. EMBO J. 31, 1931-1946

Sancho, A., Duran, J., García-España, A., Mauvezin, C., Alemu, E.A., Lamark, T., Macias, M.J., Desalle, R., Royo, M., Sala, D., Chicote, J.U., Palacín, M., Johansen, T., and Zorzano, A. 2012. DOR/Tp53inp2 and Tp53inp1 Constitute a Metazoan Gene Family Encoding Dual Regulators of Autophagy and Transcription. PLoS ONE 7, e34034. 

Lamark, T. and Johansen, T. 2012. Aggrephagy: Selective Disposal of Protein Aggregates by Macroautophagy. Int. J. Cell Biol. 2012, 736905, 21 pages. doi:10.1155/2012/736905

Aichem, A., Kalveram, B. Spinnenhirn, V., Kluge, K., Catone, N., Johansen, T. and Groettrup, M. 2012. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. J. Cell Sci. 125, 4576-4585

Pilli, M., Arko-Mensah, J., Ponpuak, M., Roberts, E., Master, S., Mandell, M.A., Dupont, N., Ornatowski, W., Jiang, S., Bradfute, S.B., Bruun, J.A., Hansen, T.E., Johansen, T. and Deretic, V. 2012. TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation. Immunity, 37, 223-234

Klionsky, D.J., .....Johansen, T.,.......Lamark, T., ........ and 1267 others. 2012. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8, 445-544.

Kleine, H., Herrmann, A., Lamark, T., Forst, A.H., Verheugd, P., Lüscher-Firzlaff, J., Lippok, B., Feijs, K.L., Herzog, N., Kremmer, E., Johansen, T., Müller-Newen, G. and Luscher B. 2012. Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62. Cell Commun. Signal. 10:28 doi:10.1186/1478-811X-10-28

Alemu, E.A.,, Lamark, T., Torgersen, K.M., Birgisdottir, A.B., Bowitz Larsen, K., Jain, A., Olsvik, H., Øvervatn, A., Kirkin, V. and Johansen, T. 2012. ATG8 Family Proteins Act as Scaffolds for Assembly of the ULK Complex: Sequence Requirements for LC3-Interacting Region (LIR) Motifs. J. Biol. Chem. 287, 39275-39290

Johansen, T. and Lamark, T. 2011. Selective autophagy mediated by autophagic adapter proteins. Autophagy, 7, 279-296.

Hansen, T.E. and Johansen, T. 2011. Following autophagy step by step. BMC Biol. 9, 39. doi:10.1186/1741-7007-9-39

Mostowy, S., Sancho-Shimizu, V., Hamon, M.A., Simeone, R., Brosch, R., Johansen, T. and Cossart P.2011. p62 and NDP52 Proteins Target Intracytosolic Shigella and Listeria to Different Autophagy Pathways. J. Biol. Chem., 286, 26987-95

Svenning, S., Lamark, T., Krause, K. and Johansen, T. 2011. Plant NBR1 is a selective autophagy substrate and a functional hybrid of the mammalian autophagic adapters NBR1 and p62/SQSTM1. Autophagy, 7, 993-1010

Elvenes, J., Thomassen, E.I.S., Sagen Johnsen, S., Kaino, K., Sjøttem, E. and Johansen, T. 2011. Pax6 Represses Androgen Receptor-Mediated Transactivation by Inhibiting Recruitment of the Coactivator SPBP. PLoS ONE 6, e24659.

Pankiv, S., Alemu, E.A., Brech, A., Bruun, J.A., Lamark, T., Øvervatn, A., Bjørkøy, G. and Johansen, T. 2010. FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport. J. Cell Biol. 188, 253-269

Pankiv, S., Lamark, T., Bruun, J.A., Øvervatn, A., Bjørkøy, G. and Johansen, T. 2010. Nucleocytoplasmic shuttling of p62/SQSTM1 and its role in recruitment of nuclear polyubiquitinitated proteins to promyelocytic leukemia bodies. J. Biol. Chem. 285, 5941-5953

Clausen, T. H., Lamark, T., Isakson, P., Finley, K., Bowitz Larsen, K., Brech, A., Øvervatn, A., Stenmark, H., Bjørkøy, G., Simonsen, A. and Johansen, T. 2010. p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy. Autophagy 6, 330-344

Filimonenko, M., Isakson, P., Finley, K.D. Anderson, M., Jeong, H., Melia, T.J., Bartlett, B.J., Myers, K.M., Birkeland, H.C., Lamark, T., Krainc, D., Brech, A., Stenmark, H., Simonsen, A., and Yamamoto, A. 2010. The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy. Mol. Cell 38, 265-279. doi:10.1016/j.molcel.2010.04.007.

Lamark, T. and Johansen, T. 2010. Autophagy: links with the proteasome. Curr. Opin. Cell Biol. 22, 192-198

Ponpuak, M., Davis, A.S., Roberts, E.A., Delgado, M.A., Dinkins, C., Zhao, Z., Virgin, H.W. 4th, Kyei, G.B., Johansen, T., Vergne, I. and Deretic, V. 2010. Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties. Immunity 32, 329-341

Pankiv, S. and Johansen, T. 2010. FYCO1: Linking autophagosomes to microtubule plus end-directing molecular motors. Autophagy 6, 550-552

Jain, A., Lamark, T., Sjøttem, E., Bowitz Larsen, K., Awuh, J.A., Øvervatn, A., McMahon, M., Hayes, J.D. and Johansen, T. 2010. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. J. Biol. Chem., 285, 22576–22591

Dikic, I. , Johansen, T. and Kirkin, V. 2010. Selective autophagy in cancer development and therapy. Cancer Res. 70, 3431-3434

Larsen, K.B., Lamark, T., Øvervatn, A., Harneshaug, I., Johansen, T. and Bjørkøy, G. 2010. A reporter cell system to monitor autophagy based on p62/SQSTM1. Autophagy 6, 784-793

Elvenes, J., Sjøttem, E., Holm, T., Bjørkøy, G. and Johansen, T. 2010. Pax6 localizes to chromatin-rich territories and displays a slow nuclear mobility altered by disease mutations. Cell. Mol. Life Sci. 67, 4079-4094

Nezis, I.P., Shravage, B.V., Sagona, A.P., Lamark, T., Bjørkøy, G., Johansen, T., Rusten, T.E., Brech, A., Baehrecke, E.H. and Stenmark, H. 2010. Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis. J. Cell. Biol. 190, 523-531

Nezis, I.P., Shravage, B.V., Sagona, A.P., Johansen, T., Baehrecke, E.H. and Stenmark, H. 2010. Autophagy as a trigger for cell death: Autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late in nurse cells during late oogenesis in Drosophila. Autophagy, 6, 1214-1215.

Alemu, E.A., Sjøttem, E., Outzen, H., Larsen, K.B., Holm, T., Bjørkøy, G., Johansen, T. 2010. Transforming growth factor-β-inducible early response gene 1 is a novel substrate for atypical protein kinase Cs. Cell. Mol. Life Sci. 68, 1953-1968

Pursiheimo, J.P., Rantanen, K., Heikkinen, P.T., Johansen, T. and Jaakkola, P.M. 2009. Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62. Oncogene 28, 334-344

Kirkin, V., Lamark, T., Sou, Y.S., Bjørkøy, G., Nunn, J.L., Bruun J-A., Shvets, E., McEwan, D.G., Clausen, T.H., Wild, P., Bilusic, I., Theurillat, J.P., Øvervatn, A., Ishii, T., Elazar, Z., Komatsu, M., Dikic, I. and Johansen, T. 2009. A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol. Cell 33, 505-516

Bjørkøy, G., Lamark, T., Pankiv, S., Øvervatn, A., Brech, A. and Johansen T. 2009. Monitoring autophagic degradation of p62/SQSTM1. Meth. Enzymol. 452, 181-197

Nezis, I. P., Lamark, T., Velentzas, A.D., Rusten, T.E., Bjørkøy, G., Johansen, T., Papassideri, I.S., Stravopodis, D.J., Margaritis, L.H., Stenmark, H. and Brech, A. 2009. Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy. Autophagy 5, 298-302

Kirkin, V., Lamark, T., Johansen, T. and Dikic, I. 2009. NBR1 co-operates with p62 in selective autophagy of ubiquitinated targets. Autophagy 5, 732-733

Lamark, T., Kirkin, V., Dikic, I. and Johansen, T. 2009. NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets. Cell Cycle 8, 1986-1990

Zheng, Y.T., Shahnazari, S., Brech, A., Lamark, T., Johansen, T. and Brumell, J.H. 2009. The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway. J. Immunol. 183, 5909-5916

Klionsky, D.J. et al.,Johansen, T. et al., Zhu X., and Deter, R. L. 2008. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4, 151-175.

Grocott, T., Frost, V., Maillard, M., Johansen, T., Wheeler, G.N., Dawes, L.J., Wormstone, I.M. and Chantry, A. 2007. The MH1 domain of Smad3 interacts with Pax6 and
represses autoregulation of the Pax6 P1 promoter. Nucleic Acids Research, 35, 890-901.

Pankiv, S., Høyvarde Clausen, T., Lamark, T., Brech, A., Bruun, J-A.,Outzen, H., Øvervatn, Bjørkøy, G. and Johansen, T. 2007. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J. Biol. Chem. 282, 24131-24145.

Sjøttem, E., Rekdal, C., Svineng, G., Sagen Johansen, S., Klenow, H., Dale Uglehus, R. and Johansen, T. 2007. The ePHD protein SPBP interacts with TopBP1 and together they co-operate to stimulate Ets1-mediated transcription. Nucleic Acids Research 35, 6648-6662.

Bjørkøy, G., Lamark, T. and Johansen, T. 2006. p62/SQSTM1: A Missing Link between Protein Aggregates and the Autophagy Machinery. Autophagy, 2, 138-9.

Erdogan, E., Lamark, T., Stallings-Mann, M., Jamieson, L., Pellechia, M., Thompson, E.A., Johansen, T. and Fields, A.P. 2006. Aurothiomalate Inhibits Transformed Growth by Targeting the PB1 Domain of Protein Kinase C iota. J. Biol. Chem. 281, 28450-28459.

Gruber, F.X., Hjorth-Hansen, H, Mikkola, I., Stenke, L. and Johansen, T. 2006. A novel Bcr-Abl splice isoform is associated with the L248V mutation in CML patients with acquired resistance to imatinib. Leukemia, 20, 2057-2060.

Gruber, F.X., Lamark, T., Anonli, A., Sovershaev, M.A., Olsen, M. Gedde-Dahl, T., Hjort-Hansen, H., and Skogen, B. 2005. Selecting and deselecting imatinib-resistant clones: observations made by longitudinal, quantitative monitoring of mutated BCR-ABL. Leukemia 19, 2159-2165. doi: 10.1038/sj.leu.2403983.

Bruun, J-A., Thomassen, E.I.S., Kristiansen, K., Tylden, G., Holm, T., Mikkola, I., Bjørkøy, G. and Johansen, T. 2005. The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions. Nucleic Acids Res., 33, 2661-2675.

Bjørkøy, G., Lamark, T., Brech, A., Outzen, H., Perander, M., Øvervatn, A., Stenmark, H. and Johansen, T. 2005. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell Biol., 171, 603-614.

Lamark, T., Perander, M., Outzen, H., Kristiansen, K., Øvervatn, A., Michaelsen, E., Bjørkøy, G. and Johansen, T. 2003. Interaction Codes within the Family of Mammalian Phox and Bem1p Domain-containing Proteins. J. Biol. Chem. 278, 34568-34581.

Lamark, T., Ingebrigtsen, M., Bjørnstad, C., Melkko, T., Mollnes, T.E., and Nielsen, E.W. 2001. Expression of active human C1 inhibitor serpin domian in Escherichia coli. Protein Expr. Purif. 22, 349-358. doi: 10.1006/prep.2001.1445.

Mikkola, I., Bruun, J-A., Holm, T. and Johansen, T. 2001. Superactivation of Pax6 mediated transactivation from paired domain-binding sites by DNA independent recruitment of different homeodomain proteins. J. Biol. Chem. 276, 4109-4118.

Perander, M., Bjørkøy, G. and Johansen, T. 2001. Nuclear import and export signals enable rapid nucleocytoplasmic shuttling of the atypical protein kinase C lambda. J. Biol. Chem. 276, 13015-13024.

Rekdal, C., Sjøttem, E. and Johansen, T. 2000. The nuclear factor SPBP contains different functional domains and stimulates the activity of various transcriptional activators. J. Biol. Chem. 275, 40288-40300.

Mikkola, I., Bruun, J-A., Bjørkøy, G., Holm, T. and Johansen, T. 1999. Phosphorylation of the transactivation domain of Pax6 by extracellular signal-regulated kinase and p38 mitogen-activated protein kinase. J. Biol. Chem. 274, 15115-15126.