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Høst 2024
KJE-3314 Organic chemistry II: reactions and selectivity - 10 stp
The course is administrated by
Institutt for kjemi
Type of course
The course is available as a singular or elective course independent of study program, also to exchange students. The course is offered on condition that a minimum number of students register for the course.
Course overlap
KJE-3301 Organic Chemistry 2 5 ects
Course contents
The theoretical part of the course will enable learning of a range of reaction types and the understanding of their chemo, regio and stereo selectivities ; (1) reactions of enolates and enolate equivalents, (2) heterocyclic chemistry, (3) rearrangements and fragmentations, (4) one-electron reactions and electrosynthesis, (5) contemporary coupling reactions and (6) C-H functionalisation and sustainable chemistry. The practical part of the course will cover laboratory safety, a selection of 4 reactions involving unique experimental techniques and conditions, advanced separation and characterisation.
Admission requirements
The course is open to candidates with a bachelor degree in natural sciences or related pharmaceutical and medical sciences with a grade C or better in the Norwegian grading system.
The course is a continuation of KJE-1002 Basic organic chemistry and KJE-1003 Organic chemistry laboratory and these, or equivalent courses elsewhere, are formal prerequisites.
Application code 9371
Obligatory prerequisites
KJE-1002 Organic chemistry, KJE-1003 Practical organic chemistry
Objective of the course
At the end of the course the student...
Knowledge
- can describe and explain reaction types from all the course topics, including a subset of named reactions
- can explain and analyse the selectivity of reactions covered in the course
- can identify a limited set of reagents, explain their functions and hypothesise their effects on the reaction outcome
- can apply knowledge of reactions and selectivities to analyse and compare different hypothetical reaction pathways
- can describe, classify and explain a set of key separation techniques
Skills
- can construct likely mechanistic proposals for the reactions covered in the course
- can predict suitable reagents for a selective transformation
- can analyse relevant theories and methods and independently solve practical and theoretical problems
- predict the outcome of course-relevant reactions and potential side reactions using mechanistic reasoning
- can solve chemical problems of relevance to course reactions and topics
- can perform selected single organic reactions in a reproducible manner under different conditions based on literature procedures
- can isolate and characterise organic compounds, and report the results in the appropriate scientific format
General competence
- can assess safety and enact appropriate practice in an organic chemistry laboratory
- can communicate with specialists and the general public on topics in organic chemistry
- can list and discuss potential ethical issues related to organic chemistry research
- can read and apply scientific literature in organic chemistry
- can relate the field of organic chemistry to one or more of the UN Sustainable Development Goal
Language of instruction
The language of instruction and examination is generally English, but Norwegian or another Scandinavian language may be used if appropriate.
Teaching methods
Micro-lectures and flipped classroom problem solving, quizzes (6), practical laboratory assignments (4 experiments). The classroom activities occur weekly (6 hrs/week).