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Høst 2023

MBI-8008 Molecular and Clinical Aspects of Cancer - Block II - 10 stp


The course is administrated by

Institutt for medisinsk biologi

Type of course

PhD course. It is available as a singular course.

PhD students and students at the Medical Student Research Program at UiT - The Arctic University of Norway apply for admission by registering for class in Studentweb by September 1st.

Application deadline for other applicants is 1 June. Application code is 9301.


Course overlap

BIO-8303 Molecular and Clinical Aspects of Cancer - block II 10 ects

Course contents

The course is divided into three modules:

Module I:

Module I cover the topics DNA repair, Transcriptional regulation, Chromatin and Epigenetics and the impact of these processes for maintenance and proper proliferation and differentiation of the cell. How dysregulation of any these processes may contribute to cancer development is discussed.

Module II:

The topics of Module II are infectious agents and their involvement in different cancer types, inflammation and cancer, and cancer stem cells. The infectious agents discussed are viruses, and how some of their encoded proteins have the ability to disturb the normal regulation of a eukaryotic cell. The inflammation section discusses the role of inflammatory factors for survival and proliferation of cancer cells. The cancer stem cell hypothesis in vascular and solid cancers will be discussed.

Module III:

Module III covers targeted cancer therapy, cancer omics and cancer epidemiology. Factors that may have a preventive effect on cancer development, immunotherapy and molecular medicines and how such

medicines specifically hit the oncoproteins and thereby inhibit growth of cancer cells are discussed. The epidemiology part highlights the impact of genetic and environmental factors in cancer development.


Admission requirements

PhD students and students at the Student Research Programme, or holders of a Norwegian master´s degree of five years or 3+2 years (or equivalent) may be admitted.

External applicants apply for the right to study by June 1st for courses that are taught in the autumn semester. Application is sent through SøknadsWeb. Please use the appliction code "9301 - Singular courses at the PhD level". If granted admission to the course students must register for class and exam in Studentweb by September 1st for autumn semester.


Objective of the course

After completing the course the students will have the

Knowledge to:

Skills to:

Competence to:


Language of instruction

English.

Teaching methods

Learning methods include lectures, seminars, presentations and self-study. The course consists of approximately 254 hours, including 30 hours of lectures, 24 hours of seminars, 120 hours reading syllabus, 20 hours for the course work requirement, and 60 hours of self-tuition (preparation for lectures and exams). The course is given each spring.