Vår 2019

MBI-3007 Eukaryotic Genes and Genomics - 10 stp

The course is administrated by

Institutt for medisinsk biologi

Type of course

Students following the master programme in biomedicine, or other students interested in the topic such as singular course students who meet the course pre-requisites.

Course overlap

MBI-3013 Human molecular genetics: medical and forensic genetics 2 stp

Course contents

The main focus in this course will be on structure, maintenance, function and regulation of the eukaryotic genome. Lectures will be given on analysis of the genome, evolution of the genome, chromosome structure and chromosome packing and the role of this in metabolic processes that involve DNA, regulation of genome activity by post-translational modifications and epigenetics, chromosomal abnormalities in relation to disease, transcriptomics and RNomics. In addition, the course will give an introduction to state of the art methods for genome analysis and genome activities.

Application deadline

Applicants from Nordic countries: 1st of December.

Admission requirements

Pre-requisites: a bachelor in biomedicine, or an equivalent bachelor degree.

Applicationcode (nordic applicants): 9371

The minimum average grade requirement is:

C - for bachelor's degree or equivalent issued in Europe, Canada, USA, Australia and New Zealand
B - for bachelor's degree or equivalent issued in all other countries

Objective of the course

The student should be able to;

- Describe the content, structure, organization, regulation and evolution of eukaryotic genes and genomes on the DNA and RNA levels.

- Describe the dynamic genome involving transposable elements, retrovirus and recombination and hypermutation in the immune system.

- Describe epigenetic mechanisms and modification of DNA and RNA.

- Describe the transcriptiome, RNA function, structure, organization, evolution and regulation.

- Explain genomic abnormalities in relation to disease.

- Give an oral presentation of a topic based on analyses of scientific articles

Language of instruction

English.

Teaching methods

The course will consist of lectures and student seminars.

Assessment

4 hours written exam, graded alphabetically A-F.

Students must pass the coursework requirements in the form of a student presentation of a topic based on analyses of scientific articles in order to be able to attend the final examination.

A re-sit exam/postponed exam will be arranged early in the following semester, for candidates who failed the exam, or who, for valid reasons, were unable to attend.