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Høst 2016
BIO-3609 Basal and Comparative Immunology - 10 stp
The course is administrated by
Norges fiskerihøgskole
Type of course
The course can be taken as a singular course.
Course contents
This course aims to provide an understanding of the components and principal workings of the vertebrate immune system and the lectures will focus both on mammalian species and on fish. The course will particularly discuss on how the immune system protects the body from microorganisms like virus, bacteria, fungi and parasites. We will also examine how immune responses are initiated and terminated, how the immune system "remembers" a pathogenic intruder such that it can respond stronger at subsequent infections (the basis for vaccination). We will also discuss the basis for the immune system to recognize virtually any structure it is exposed to and why the immune system will vigorously reject transplanted foreign tissues.
Admission requirements
Student must have pre-knowledge corresponding to BIO-1001 Cell and molecular biology, and BIO-2601 General microbiology.
Obligatory prerequisites
BIO-2601 General microbiology, MBI-1001 Cell and molecular biology
Objective of the course
Knowledge: The Candidate
- knows the key differences between innate and adaptive immunity
- knows the principal organization of lymphoid organs of mammals and fish
- knows about the most important immunological cell types and their effector mechanisms
- which function various cytokines and the complement system has
- knows the essential immune molecules - B and T cell receptors and MHC Class I and II
- understand the mechanisms that provide the B and T cells with the great repertoire of molecule detection
- have knowledge about the principles for clonal selection of antigen-specific lymphocytes
- know the main differences in the defense against bacteria and viruses
- is able to understand the immunological principles that vaccines is built on
Skills: The Candidate can
- evaluate the effects of different prophylactic treatments including vaccines and vaccination strategies
- evaluate the impact of different immunological parameters, i.e. antibody responses and immune gene profiling by qPCR
General knowledge: The Candidate
- have a good overview of the immune system of higher vertebrates (mammals and fish)
Language of instruction
English.
Teaching methods
Lectures and seminars.
Assessment
Three hours written exam. A - E for passed, F for failed.
A re-sit exam will be arranged for this course.
Date for examination
One written 05.12.2016
The date for the exam can be changed. The final date will be announced at your faculty early in May and early in November.
Recommended reading/syllabus
The course text book is: Basic Immunology: Functions and disorders of the immune system. Abul K. Abbas & Andrew H. Lichtman. Third Edition. Review papers within fish immunology will be presented at the course.
Lecture presentations are also considered required reading.