KJE-2004 Bioinformatics - An introduction - 10 stp

Applicants from Nordic countries: Generell studiekompetanse + Matematikk R1 eller (S1+S2) og enten Matematikk (R1+R2) eller Fysikk (1+2) eller Kjemi (1+2) eller Biologi (1+2) eller Informasjonsteknologi( 1+2) eller Geologi (1+2) eller Teknologi og forskningslære (1+2).

International applicants: Higher Education Entrance Qualification and certified language requirements in English. It is a requirement that students have  some prior knowledge of biology and ecology, chemistry and mathematics (Participants must have taken introductory level university courses, and achieved pass grades, in these subjects).

A list of the requirements for the Higher Education Entrance Qualification in Norway can be found on the Norwegian Agency for Quality Assurance in Education website - nokut.no

Application code: 9336 (Nordic applicants).

Knowledge:

The candidate

Background basics: •

• has basic knowledge about DNA and RNA structure, the central dogma, gene structure and control, and the tree of life and evolution.
• •has basic knowledge about primary and secondary protein structure, and implications for bioinformatics. •
• has insights into structure of databases, types of databases, and data quality.

Sequence alignments: •

• knows the principals of sequence alignments.
• •has knowledge about pairwise sequence alignments and database searching. •
• has knowledge about patterns, profiles and multiple sequence alignments.

Evolutionary processes:

• •has knowledge into basic principles of structure and interpretation of phylogenetic trees •
• has knowledge about how to reconstruct phylogenetic trees

Genome characteristics: •

• has knowledge about general genome features. •
• knows how to predict genes, splice sites, promoters.
• •has knowledge into algorithms for detecting genes, introns/exons.

Secondary structures: •

• has knowledge about how to obtain structure information from primary sequence.

Tertiary structures: •

• knows the most important techniques for determination of protein structure modelling. •
• knows how to analyse structure-function relationships.

Cells and organisms: •

• has knowledge about how to analyse proteome and transcriptome data.
• •has knowledge about clustering methods. •
• has knowledge about systems biology.

Skills:

The candidate  

• can describe the properties of DNA and RNA.
• can explain the central dogma, and is able to outline structures and types of databases.
• •can score alignments, use search tools, reflect on substitution matrices, profiles and hidden Markov models. •
• can carry out phylogenetic analyses and interpret the results.
• •is able to recognize typical gene features. •
• can predict and assess secondary structures from sequence. •
• can outline sequencing and expression profiling techniques. •
• can present academic material

General competence:

The candidate •

• understands the relation between DNA, RNA and protein, and can use this information to discuss their function. •
• can participate in discussions concerning bioinformatics with others. •
• has the ability to plan and execute basic bioinformatics tasks; aligning and handling sequences, database searching, phylogenetic analysis, and basic annotation.
• •can interpret and communicate scientific material on bioinformatics.

The date for the exam can be changed. The final date will be announced at your faculty early in May and early in November.