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KJE-3308 Metal-Organic Compounds in Organic Synthesis - 10 ECTS
Organometallic chemistry is the chemistry of transition metals used in organic synthesis and is routinely used by synthetic chemists.
The course starts with the description of organometallic complexes in terms of electron configuration, bonding and structure. Reaction mechanisms and reactivity of complexes containing different transition metals and ligands are then introduced and applied in the analysis of complex synthetic transformations.
The student will have acquired a solid and broad theoretical basis to understand metallo-organic chemistry. This means that the student
- knows how to use the 18-electron rule
- understands how to determine the oxidation state of metals in complexes
- has an understanding of bonding in organometallic complexes
- recognizes different organometallic reaction mechanisms
- has knowledge about the most common named organometallic reactions
- knows how to draw reaction mechanisms for organometallic reactions
- knows how to compare the reactivity of catalysts
- recognizes the most common named reactions
- can deduce the reaction mechanism of organometallic reactions
- knows how to choose organometallic reagents for complex transformations
- can follow reaction sequences in scientific literature