Master of Science Jostein Grip disputerer for ph.d.-graden i helsevitenskap og vil offentlig forsvare avhandlingen:
“Development of novel wound dressings with soluble beta-glucan (SBG®) as an active ingredient”
Kort sammendrag av avhandlingen:
The increased prevalence of obesity and diabetes are co-morbidities that increase the risk of developing chronic wounds, e.g. venous leg ulcers and diabetic foot ulcer. The goal of this industry sponsored PhD Thesis was to develop complimentary wound healing products to the commercially available Woulgan® Gel using the proprietary β-glucan SBG® for treatment of chronic wounds.
We have developed a spray and a nanofiber formulation for treatment of hard-to-heal wounds, and tested these formulations in vivo on diabetic mice with full thickness wounds. The spray and nanofiber formulations developed in this Thesis exhibit attributes that can be valuable in a clinical setting. Thus, both dressings exhibited strong potential for commercialization on an industrial scale.
Veiledere
Hovedveileder førsteamanuensis Ann Mari Holsæter Biveileder professor Nataša Škalko-Basnet
Biveileder Forskningsdirektør, dr. Rolf Engstad, Biotec BetaGlucans AS
Biveileder Scientific product manager, dr. Ingrid Skjæveland, Biotec BetaGlucans AS
Bedømmelseskomiteen
Professor Jyrki Tapio Heinämäki, University of Tartu, Estonia – 1. opponent
Førsteamanuensis Anita Hafner, University of Zagreb, Croatia – 2. opponent
Førsteamanuensis II Jon Våbenø, Institutt for Farmasi, UiT Norges arktiske universitet – leder av komité
Disputasleder
Førsteamanuensis Lars Småbrekke, Institutt for farmasi, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet
Prøveforelesning over oppgitt emne holdes kl. 10.15, samme sted: “Applications of biopolymers in chronic wound treatment”