Inflammatory bowel diseases (IBD) are chronic diseases of unknown cause which have major health consequences. The ASIB study is a translation research project aiming to investigate underlying causes leading to the disease. Moreover we aim to develop new tests (measurable biomarkers) that can be used as an aid to guide decisions when treating the disease.
The follow-up and treatment of IBD is complex and often involve specialist care. The ASIB study aim to gain insights in mechanisms behind IBD and how to tailor the best treatment for each individual patient.
For this purpose, we have built a large biobank of biological samples. These are primarily samples from the mucosal lining of patients with IBD, collected at routine examinations (endoscopy). Using these samples we can analyse a vast array of different substances within genetic, protein, and metabolites – so-called “omics” platforms where a multitude of compounds can be measured simultaneously. These analyses are performed in collaboration with partners at University of Copenhagen, NTNU and UiT.
Important sub-projects address aspects like
During the active years the project has received funding from HelseNord, Norwegian Research Council, and MABIT.