Cancer-associated fibroblast role in responses of lung tumors to radiotherapy and immunotherapy
Our experimental strategy includes both in vitro functional studies with primary cell cultures, and in vivo approaches in xenograft models. Experiments at the laboratory are performed with freshly resected human tumor cells obtained from resected tumor samples. Our methodology includes a wide range of molecular and cell biological techniques including high-throughput gene and protein profiling, specific gene and protein determination, cell and tissue imaging and functional cell assays. At the in vivo front, the recent acquisition of a pre-clinical image-guided radiation unit will be central in our experimentation, and analyses of xenograft tumors by bioluminescent and/or PET/CT imaging, histology, immunohistochemistry and immunocytochemistry will constitute complementary methodology.
Professor Inigo Martinez, firstname.lastname@example.org, 776 45449/44686.
Senior researcher Turid Hellevik, email@example.com, 776 26 187.