079d428.jpg

Flag icon Flag icon

Espen Åberg

Forsker/Senter for Bioinformatikk (SfB)
Institutt for kjemi

Stillingsbeskrivelse:

Espen Åberg har sin bakgrunn i molekylær bioteknologi med en doktorgrad i molekylær medisin. Etter doktorgradsutdanningen spesialiserte han seg på biologiske signalnettverk, menneskelig og malariakinomikk og legemiddeldesign før han byttet til kreft genomikk ved Norwegian Cancer Genomics Consortium. Han gikk deretter videre til bioinformatisk arbeid, med fokus på genomikk og samspillet mellom vert og mikrober under kolonisering og infeksjon. Han er for tiden ansatt ved ELIXIR Norge som forsker og gjør metagenomiske analyser samt kursing ved Senter for bioinformatikk, UiT, Det arktiske universitetet i Norge (UiT).




Forskningsinteresser

Bioinformatikk, metagenomikk, genomikk

Undervisning

BIO-3323 Bioinformatics: Genomes and genomics

KJE-8602 Bioinformatics - genome and genome analysis

First Marine Microbiome workshop Metagenomics and Bioinformatics for Biodiversity, Nador, Morocco

Elixir-Excelerate Workshop on Marine Metagenomics, May 2018, Oeiras Portugal

Arbeider i CRIStin


  • Ajayi, Clement; Åberg, espen; Askarian, Fatemeh; Sollid, Johanna U Ericson; Johannessen, Mona; Hanssen, Anne Merethe. Genetic variability in the sdrD gene in Staphylococcus aureus from healthy nasal carriers.. BMC Microbiology 2018; Volum 18 (34). ISSN 1471-2180.s doi: 10.1186/s12866-018-1179-7.

  • Alexeeva, Marina; Åberg, espen; Engh, Richard Alan; Rothweiler, Ulli. The structure of a dual-specificity tyrosine phosphorylation-regulated kinase 1A-PKC412 complex reveals disulfide-bridge formation with the anomalous catalytic loop HRD(HCD) cysteine.. Acta Crystallographica Section D: Biological Crystallography 2015; Volum 71. ISSN 0907-4449.s 1207 - 1215.s doi: 10.1107/S1399004715005106.

  • Åberg, espen; Lund, Bjarte Aarmo; Pflug, Alexander; Gani, Osman A.B.S.M.; Rothweiler, Ulli; Oliveira, Taiana Maia De; Engh, Richard Alan. Structural origins of AGC protein kinase inhibitor selectivities: PKA as a drug discovery tool. Biological chemistry 2012; Volum 393 (10). ISSN 1431-6730.s 1121 - 1129.s doi: 10.1515/hsz-2012-0248.

  • von Bubnoff, N.; Gorantla, S.P.; Engh, Richard Alan; Oliveira, Taiana Maia De; Thöne, S.; Åberg, espen; Peschel, C.; Duyster, J.. The low frequency of clinical resistance to PDGFR inhibitors in myeloid neoplasms with abnormalities of PDGFRA might be related to the limited repertoire of possible PDGFRA kinase domain mutations in vitro. Oncogene 2011; Volum 30 (8). ISSN 0950-9232.s 933 - 943.s doi: 10.1038/onc.2010.476.

  • Rothweiler, Ulli; Åberg, espen; Johnson, Kenneth; Hansen, Tom Egil; Jørgensen, Jorunn B; Engh, Richard Alan. p38 alpha MAP Kinase Dimers with Swapped Activation Segments and a Novel Catalytic Loop Conformation. Journal of Molecular Biology 2011; Volum 411 (2). ISSN 0022-2836.s 474 - 485.s doi: 10.1016/j.jmb.2011.06.013.

  • Åberg, espen; Torgersen, Knut Martin; Johansen, Bjarne Herold; Keyse, Stephen M; Perander, maria; Seternes, ole morten. Docking of PRAK/MK5 to the Atypical MAPKs ERK3 and ERK4 Defines a Novel MAPK Interaction Motif. Journal of Biological Chemistry 2009; Volum 284 (29). ISSN 0021-9258.s 19392 - 19401.s doi: 10.1074/jbc.M109.023283.

  • von Bubnoff, N; Engh, Richard Alan; Åberg, espen; Sanger, J; Peschel, C; Duyster, J. FMS-Like Tyrosine Kinase 3-Internal Tandem Duplication Tyrosine Kinase Inhibitors Display a Nonoverlapping Profile of Resistance Mutations In vitro. Cancer Research 2009; Volum 69 (7). ISSN 0008-5472.s 3032 - 3041.s doi: 10.1158/0008-5472.CAN-08-2923.

  • Perander, maria; Åberg, espen; Johansen, Bjarne Herold; Dreyer, Bo; Guldvik, Ingrid Jenny; Outzen, heidi; Keyse, Stephen M; Seternes, ole morten. The Ser(186) phospho-acceptor site within ERK4 is essential for its ability to interact with and activate PRAK/MK5. Biochemical Journal 2008; Volum 411. ISSN 0264-6021.s 613 - 622.s doi: 10.1042/BJ20071369.

  • Michaelsen, espen; Perander, maria; Johansen, Bjarne Herold; Julien, Catherine; Meloche, Sylvain; Keyse, Stephen M; Seternes, ole morten. Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAPK ERK4/MAPK4. Journal of Biological Chemistry 2006; Volum 281 (46). ISSN 0021-9258.s 35499 - 35510.

  • Seternes, Ole Morten; Mikalsen, Theresa; Johansen, Bjarne; Michaelsen, Espen; Armstrong, CG; Morrice, NA; Turgeon, B; Meloche, S; Moens, Ugo Lionel; Keyse, SM. Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway. EMBO Journal 2004; Volum 23 (24). ISSN 0261-4189.s 4780 - 4791.s doi: 10.1038/sj.emboj.7600489.

  • Ajayi, Clement; Åberg, espen; Askarian, Fatemeh; Sollid, Johanna U Ericson; Johannessen, Mona; Hanssen, Anne-Merethe. Genetic variability in the sdrD gene in Staphylococcus aureus from healthy nasal carriers. IBA - annual meeting 2017 2017-11-13 - 2017-11-14 2017.

  • Alexeeva, Marina; Åberg, espen; Engh, Richard Alan; Rothweiler, Ulli. The structure of a dual-specificity tyrosine phosphorylation-regulated kinase 1A-PKC412 complex reveals disulfide-bridge formation with the anomalous catalytic loop HRD(HCD) cysteine.. Contact Meeting 2016 2016-01-21 - 2016-01-24 2016.

  • Åberg, espen; Seternes, Ole Morten; Engh, Richard Alan; Gruber, Franz. Fra Mutasjon til Medisin. Forskningsdagene i Tromsø 2013 - Kreftforeningens Stand 2013-09-20 - 2013-09-21 2013.

  • von Bubnoff, N; Gorantla, SP; Engh, Richard Alan; de Oliveira, Taianá Maia; Thoene, S; Åberg, espen; Peschel, C; Duyster, J. Sorafenib and Nilotinib Are Candidates to Overcome Imatinib Resistance in Myeloproliferation with FIP1L1-PDGFRA. Blood 2009; Volum 114 (22). ISSN 0006-4971.s 1138 - 1138.

  • Åberg, Espen; Perander, maria; Johansen, Bjarne Herold; Julien, Catherine; Meloche, Sylvain; Keyse, Stephen M; Seternes, ole morten. Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAP kinase ERK4/MAPK4. 15th Protein Kinase Meeting 2006-09-21 - 2006-09-24 2006.