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Eyvind Jakob Paulssen

Professor II
Institutt for klinisk medisin




Forskningsinteresser

Fordøyelsessykdommer, inklusive smittsomme leverbetennelser, inflammatorisk tarmsykdom, overvekt og dens komplikasjoner.

CV

Cand.med., Universitetet i Oslo, 1985

Dr. med., Universitetet i Oslo, 1992

Spesialist i indremedisin og fordøyelsessykdommer 2001

Førsteamanuensis II, IKM 2006-2010

Professor II, IKM, 2010 -

Arbeider i CRIStin


  • Kileng, Hege; Gutteberg, Tore Jarl; Goll, Rasmus; Paulssen, Eyvind Jakob. Screening for hepatitis C in a general adult population in a low-prevalence area: the Tromsø study. BMC Infectious Diseases 2019; Volum 19 (189). ISSN 1471-2334.s doi: 10.1186/s12879-019-3832-7.

  • Larsen, Maria Arlen; Isaksen, Victoria Therese; Paulssen, Eyvind Jakob; Goll, Rasmus; Florholmen, Jon. Postprandial leptin and adiponectin in response to sugar and fat in obese and normal weight individuals. (data) (fulltekst) Endocrine (Basingstoke) 2019. ISSN 1355-008X.s 1 - 9.s doi: 10.1007/s12020-019-02102-9.

  • Olsøy, Irene Beate; Henriksen, Stian; Weissbach, Fabian H.; Larsen, Marthe; Borgen, Karoline; Abravanel, Florence; Kamar, Nassim; Paulssen, Eyvind Jakob; Hirsch, Hans H.; Rinaldo, Christine Hanssen. Seroprevalence of hepatitis E virus (HEV) in a general adult population in Northern Norway: the Tromsø study. Medical Microbiology and Immmunology 2019. ISSN 0300-8584.s doi: 10.1007/s00430-019-00599-5.

  • Larsen, Maria Arlen; Isaksen, Victoria Therese; Moen, Odd; Wilsgård, Line; Remjin, Marian; Paulssen, Eyvind Jakob; Florholmen, Jon; Goll, Rasmus. Leptin to adiponectin ratio - A surrogate biomarker for early detection of metabolic disturbances in obesity. NMCD. Nutrition Metabolism and Cardiovascular Diseases 2018. ISSN 0939-4753.s 1 - 8.s doi: 10.1016/j.numecd.2018.06.020.

  • Johnsen, Kay-Martin; Goll, Rasmus; Hansen, Vegar; Olsen, Trine; Rismo, Renathe; Heitmann, Richard; Gundersen, Mona Dixon; Kvamme, Jan-Magnus; Paulssen, Eyvind Jakob; Kileng, Hege; Johnsen, Knut; Florholmen, Jon. Repeated intensified infliximab induction – results from an 11-year prospective study of ulcerative colitis using a novel treatment algorithm. European Journal of Gastroenterology and Hepathology 2017; Volum 29 (1). ISSN 0954-691X.s 98 - 104.s doi: 10.1097/MEG.0000000000000753.

  • Kileng, Hege; Bernfort, Lars; Gutteberg, Tore Jarl; Moen, Odd Sverre; Kristiansen, Magnhild Gangsøy; Paulssen, Eyvind Jakob; Berg, Leif Kyrre; Florholmen, Jon; Goll, Rasmus. Future complications of chronic hepatitis C in a low-risk area: Projections from the hepatitis c study in Northern Norway. BMC Infectious Diseases 2017; Volum 17:624. ISSN 1471-2334.s 1 - 9.s doi: 10.1186/s12879-017-2722-0.

  • Olsen, Trine; Rismo, Renathe; Gundersen, Mona Dixon; Paulssen, Eyvind Jakob; Johnsen, Knut; Kvamme, Jan-Magnus; Goll, Rasmus; Florholmen, Jon. Normalization of mucosal tumor necrosis factor-α: A new criterion for discontinuing infliximab therapy in ulcerative colitis. Cytokine 2016; Volum 79. ISSN 1043-4666.s 90 - 95.s doi: 10.1016/j.cyto.2015.12.021.

  • Breckan, Ragnar K; Paulssen, Eyvind Jakob; Asfeldt, Anne Mette; Kvamme, Jan-Magnus; Straume, Bjørn; Florholmen, Jon. The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study. Helicobacter 2016; Volum 21 (6). ISSN 1083-4389.s 586 - 595.s doi: 10.1111/hel.12316.

  • Isaksen, Victoria Therese; Larsen, Maria Arlen; Goll, Rasmus; Florholmen, Jon; Paulssen, Eyvind Jakob. Hepatic steatosis, detected by hepatorenal index in ultrasonography, as a predictor of insulin resistance in obese subjects. BMC Obesity 2016; Volum 3 (39). ISSN 2052-9538.s doi: 10.1186/s40608-016-0118-0.

  • Rismo, Renathe; Olsen, Trine; Cui, Guanglin; Paulssen, Eyvind Jakob; Christiansen, Ingrid B; Johnsen, Knut; Florholmen, Jon; Goll, Rasmus. Normalization of mucosal cytokine gene expression levels predicts long-term remission after discontinuation of anti-TNF therapy in Crohn's disease. Scandinavian Journal of Gastroenterology 2013; Volum 48 (3). ISSN 0036-5521.s 311 - 319.s doi: 10.3109/00365521.2012.758773.

  • Valle, Per Christian; Breckan, ragnar k; Mortensen, Liisa; Amin, Anil; Kildahl-Andersen, Odd A; Paulssen, Eyvind Jakob. Managing dyspepsia in the young adult patient: effects of different tests for Helicobacter pylori in a "test-and-scope" approach. Scandinavian Journal of Gastroenterology 2013; Volum 48 (8). ISSN 0036-5521.s 913 - 920.s doi: 10.3109/00365521.2013.800988.

  • Rismo, Renathe; Olsen, Trine; Cui, Guanglin; Paulssen, Eyvind Jakob; Christiansen, ingrid b; Florholmen, Jon; Goll, Rasmus. The effect of adalimumab for induction of endoscopic healing and normalization of mucosal cytokine gene expression in Crohn's disease. Scandinavian Journal of Gastroenterology 2012; Volum 47 (10). ISSN 0036-5521.s 1200 - 1210.s doi: 10.3109/00365521.2012.711853.

  • Breckan, ragnar k; Asfeldt, anne mette; Straume, Bjørn; Florholmen, Jon; Paulssen, Eyvind Jakob. Prevalence, comorbidity, and risk factors for functional bowel symptoms: a population-based survey in Northern Norway. Scandinavian Journal of Gastroenterology 2012; Volum 47 (11). ISSN 0036-5521.s 1274 - 1282.s doi: 10.3109/00365521.2012.688215.

  • Florholmen, Jon; Kristiansen, Magnhild Gangsøy; Steigen, Sonja Eriksson; Sørbye, Sveinung Wergeland; Paulssen, Eyvind Jakob; Kvamme, Jan-Magnus; Zbigniew, Konopski; Gutteberg, Tore Jarl; Goll, Rasmus. A rapid chemokine response of macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and the regulated on activation, normal T expressed and secreted chemokine is associated with a sustained virological response in the treatment of chronic hepatitis C. Clinical Microbiology and Infection 2011; Volum 17 (2). ISSN 1198-743X.s 204 - 209.s doi: 10.1111/j.1469-0691.2010.03206.x.

  • Olsen, Karina; Dahl, Per Erling; Paulssen, Eyvind Jakob; Husebekk, Anne; Widell, Anders; Busund, Rolf. Increased risk of transmission of hepatitis C in open heart surgery compared with vascular and pulmonary surgery. Annals of Thoracic Surgery 2010; Volum 90. ISSN 0003-4975.s 1425 - 1431.s doi: 10.1016/j.athoracsur.2010.06.053.

  • Asfeldt, anne mette; Steigen, sonja eriksson; Lochen, ML; Løchen, Maja-Lisa; Straume, Bjørn; Johnsen, roar; Bernersen, Bjørn; Florholmen, Jon; Paulssen, Eyvind Jakob. The natural course of Helicobacter pylori infection on endoscopic findings in a population during 17 years of follow-up: the Sorreisa gastrointestinal disorder study. (fulltekst) European Journal of Epidemiology (EJE) 2009; Volum 24 (10). ISSN 0393-2990.s 649 - 658.s doi: 10.1007/s10654-009-9371-6.

  • Breckan, ragnar k; Paulssen, Eyvind Jakob; Asfeldt, anne mette; Mortensen, Liisa; Straume, Bjørn; Florholmen, Jon. The impact of body mass index and Helicobacter pylori infection on gastro-oesophageal reflux symptoms: A population-based study in Northern Norway. Scandinavian Journal of Gastroenterology 2009; Volum 44 (9). ISSN 0036-5521.s 1060 - 1066.s doi: 10.1080/00365520903093728.

  • Asfeldt, anne mette; Straume, Bjørn; Steigen, sonja eriksson; Lochen, ML; Løchen, Maja-Lisa; Florholmen, Jon; Bernersen, Bjørn; Johnsen, roar; Paulssen, Eyvind Jakob. Changes in the prevalence of dyspepsia and Helicobacter pylori infection after 17 years: The Sorreisa gastrointestinal disorder study. European Journal of Epidemiology (EJE) 2008; Volum 23. ISSN 0393-2990.s 625 - 633.s doi: 10.1007/s10654-008-9275-x.

  • Paulssen, Eyvind Jakob; Lindsetmo, Rolv-Ole. Long-term outcome of endoluminal gastroplication in the treatment of gastro-oesophageal reflux disease: Effect of a second procedure. Scandinavian Journal of Gastroenterology 2008; Volum 43. ISSN 0036-5521.s 5 - 12.s doi: 10.1080/00365520701514560.

  • Asfeldt, anne mette; Straume, Bjørn; Paulssen, Eyvind Jakob. Impact of observer variability on the usefulness of endoscopic images for the documentation of upper gastrointestinal endoscopy. Scandinavian Journal of Gastroenterology 2007; Volum 42. ISSN 0036-5521.s 1106 - 1112.s doi: 10.1080/00365520701259240.

  • Gordeladze, Jan Oxholm; Haugen, Trine B.; Paulssen, Eyvind Jakob; Paulssen, Ruth H. Phospholipase C activation in rat pituitary adenoma (GH) cells.. Bioscience Reports 1996; Volum 16 (1). ISSN 0144-8463.s 65 - 74.

  • Paulssen, Ruth H; Johansen, Per Wiik; Gordeladze, Jan Oxholm; Nymoen, Ole-Martin; Paulssen, Eyvind Jakob; Gautvik, Kaare M. Cell-specific expression and function of adenylyl cyclases in rat pitruitary tumour cell lines. European Journal of Biochemistry (EJB) 1994; Volum 222 (1). ISSN 0014-2956.s 97 - 103.

  • Paulssen, Ruth H; Paulssen, Eyvind Jakob; Gautvik, Kaare M; Gordeladze, Jan Oxholm. Modulation of G proteins and second messenger responsiveness by steroid hormones in GH3 rat pituitary tumour cells. Acta Physiologica Scandinavica 1992; Volum 146 (2). ISSN 0001-6772.s 511 - 518.

  • Paulssen, Eyvind Jakob; Paulssen, Ruth H; Gautvik, Kaare M; Gordeladze, Jan Oxholm. "Cross-talk" between phospholipase C and adenylyl cyclase involves regulation of G-protein levels in GH3 rat pituitary cells. Cellular Signalling 1992; Volum 4 (6). ISSN 0898-6568.s 747 - 755.

  • Paulssen, Eyvind Jakob; Paulssen, Ruth H; Gautvik, Kaare M; Gordeladze, Jan Oxholm. Hypothalamic hormones modulate G protein levels and second messenger responsiveness in GH3 rat pituitary tumour cells. Biochemical Pharmacology 1992; Volum 44 (3). ISSN 0006-2952.s 471 - 477.

  • Paulssen, Ruth H; Paulssen, Eyvind Jakob; Gautvik, Kaare M; Gordeladze, Jan Oxholm. The thyroliberin receptor interacts directly with a stimulatory guanine-nucleotide-binding protein in the activation of adenylyl cyclase in GH3 rat pituitary tumour cells. Evidence obtained by use of antisense RNA inhibition and immunoblocking of the stimulatory guanine-nucleotide-binding protein. European Journal of Biochemistry (EJB) 1992; Volum 204 (1). ISSN 0014-2956.s 413 - 418.

  • Paulssen, Ruth H; Paulssen, Eyvind Jakob; Gordeladze, Jan Oxholm; Hansson, Vidar; Haugen, Trine B.. Cell-specific expression of guanine nucleotide-binding proteins in rat testicular cells. Biology of Reproduction 1991; Volum 45 (4). ISSN 0006-3363.s 566 - 571.

  • Paulssen, Eyvind Jakob; Paulssen, Ruth H; Haugen, Trine B.; Gautvik, Kaare M; Gordeladze, Jan Oxholm. Regulation of G protein mRNA levels by thyroliberin, vasoactive intestinal peptide and somatostatin in prolactin-producing rat pituitary adenoma cells. Acta Physiologica Scandinavica 1991; Volum 143 (2). ISSN 0001-6772.s 195 - 201.

  • Parrow, VC; Gordeladze, Jan Oxholm; Paulssen, Eyvind Jakob; Alestrøm, Peter; Gautvik, Kaare M. Signal transduction alterations in GH(1)2C1 rat pituitary tumour cells following treatment with 5-azacytidine. Journal of Molecular Endocrinology 1991; Volum 6 (3). ISSN 0952-5041.s 257 - 268.

  • Paulssen, Eyvind Jakob; Paulssen, Ruth H; Haugen, Trine B.; Gautvik, Kaare M; Gordeladze, Jan Oxholm. Cell specific distribution of guanine nucleotide-binding regulatory proteins in rat pituitary tumour cell lines. Molecular and Cellular Endocrinology 1991; Volum 76 (1-3). ISSN 0303-7207.s 45 - 53.

  • Paulssen, Ruth H; Paulssen, Eyvind Jakob; Alestrøm, Peter; Gordeladze, Jan Oxholm; Gautvik, Kaare M. Specific antisense RNA inhibition of growth hormone production in differentiated rat pituitary tumour cells. Biochemical and Biophysical Research Communications - BBRC 1990; Volum 171 (1). ISSN 0006-291X.s 293 - 300.

  • Haugen, Trine B.; Paulssen, Eyvind Jakob; Gordeladze, Jan Oxholm; Hansson, Vidar. A unique mRNA species of the alpha subunit of Gs is present in rat haploid germ cells. Biochemical and Biophysical Research Communications - BBRC 1990; Volum 168 (1). ISSN 0006-291X.s 91 - 98.

  • Gordeladze, Jan Oxholm; Paulssen, Eyvind Jakob; Hracky, Ruth. G-proteins and their involvement in hormonal signal transduction. Scandinavian Journal of Clinical and Laboratory Investigation 1990; Volum 202. ISSN 0036-5513.s 127 - 130.

  • Paulssen, Eyvind Jakob. Hepatitt C – en stille epidemi i Tromsø?. (data) 2015.

  • Paulssen, Eyvind Jakob. Intervju i bladet Nordlys 17.06.13. Førstesideoppslag og artikkel i bladet. 2013.

  • Breckan, ragnar k; Asfeldt, anne mette; Paulssen, Eyvind Jakob; Straume, Bjørn; Mortensen, L.; Florholmen, Jon. The correlation between Helicobacter pylori infection, body mass index, and reflux symptoms in healthy subjects. Helicobacter 2007; Volum 12. ISSN 1083-4389.s 421 - 421.

  • Paulssen, Ruth H; Paulssen, Eyvind Jakob; Gordeladze, Jan Oxholm; Gautvik, Kaare M. The elucidation of receptor-effector coupling in rat pituitary (GH3) cells by the use of antisense techniques. Journal of Cellular Biochemistry 1991. ISSN 0730-2312.s 26 - .

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