Publikasjoner utenfor Cristin
Publications 1999-2015
Mikkola, I., Bruun, J-A., Bjørkøy, G., Holm, T. and Johansen, T. 1999. Phosphorylation of the transactivation domain of Pax6 by extracellular signal-regulated kinase and p38 mitogen-activated protein kinase. Journal of Biological Chemistry, 274, 15115-15126.
Rekdal, C., Sjøttem, E. and Johansen, T. 2000. The nuclear factor SPBP contains different functional domains and stimulates the activity of various transcriptional activators. Journal of Biological Chemistry, 275, 40288-40300.
Mikkola, I., Bruun, J-A., Holm, T. and Johansen, T. 2001. Superactivation of Pax6 mediated transactivation from paired domain-binding sites by DNA independent recruitment of different homeodomain proteins. Journal of Biological Chemistry, 276, 4109-4118.
Perander, M., Bjørkøy, G. and Johansen, T. 2001. Nuclear import and export signals enable rapid nucleocytoplasmic shuttling of the atypical protein kinase C lambda. Journal of Biological Chemistry, 276, 13015-13024.
Lamark, T., Perander, M., Outzen, H., Kristiansen, K., Øvervatn, A., Michaelsen, E., Bjørkøy, G. and Johansen, T. 2003. Interaction Codes within the Family of Mammalian Phox and Bem1p Domain-containing Proteins. Journal of Biological Chemistry, 278, 34568-34581.
Bruun, J-A., Thomassen, E.I.S., Kristiansen, K., Tylden, G., Holm, T., Mikkola, I., Bjørkøy, G. and Johansen, T. 2005. The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions. Nucleic Acids Res., 33, 2661-2675.
Bjørkøy, G., Lamark, T., Brech, A., Outzen, H., Perander, M., Øvervatn, A., Stenmark, H. and Johansen, T. 2005. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell Biol., 171, 603-614.
Bjørkøy, G., Lamark, T. and Johansen, T. 2006. p62/SQSTM1: A Missing Link between Protein Aggregates and the Autophagy Machinery. Autophagy , 2, 138-9.
Erdogan, E., Lamark, T., Stallings-Mann, M., Jamieson, L., Pellechia, M., Thompson, E.A., Johansen, T. and Fields, A.P. 2006. Aurothiomalate Inhibits Transformed Growth by Targeting the PB1 Domain of Protein Kinase C iota. Journal of Biological Chemistry, 281, 28450-28459.
Gruber, F.X., Hjorth-Hansen, H, Mikkola, I., Stenke, L. and Johansen, T. 2006. A novel Bcr-Abl splice isoform is associated with the L248V mutation in CML patients with acquired resistance to imatinib. Leukemia, 20, 2057-2060.
Grocott, T., Frost, V., Maillard, M., Johansen, T., Wheeler, G.N., Dawes, L.J., Wormstone, I.M. and Chantry, A.2007. The MH1 domain of Smad3 interacts with Pax6 and
represses autoregulation of the Pax6 P1 promoter. Nucleic Acids Research, 35, 890-901.
Pankiv, S., Høyvarde Clausen, T., Lamark, T., Brech, A., Bruun, J-A.,Outzen, H., Øvervatn, Bjørkøy, G. and Johansen, T. 2007. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J. Biol. Chem.282, 24131-24145.
Sjøttem, E., Rekdal, C., Svineng, G., Sagen Johansen, S., Klenow, H., Dale Uglehus, R. and Johansen, T. 2007. The ePHD protein SPBP interacts with TopBP1 and together they co-operate to stimulate Ets1-mediated transcription. Nucleic Acids Research 35, 6648-6662.
Klionsky, D.J. et al.,Johansen, T. et al., Zhu X., and Deter, R. L. 2008. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4, 151-175.
Pursiheimo, J.P., Rantanen, K., Heikkinen, P.T., Johansen, T. and Jaakkola, P.M. 2009. Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62. Oncogene 28, 334-344
Kirkin, V., Lamark, T., Sou, Y.S., Bjørkøy, G., Nunn, J.L., Bruun J-A., Shvets, E., McEwan, D.G., Clausen, T.H., Wild, P., Bilusic, I., Theurillat, J.P., Øvervatn, A., Ishii, T., Elazar, Z., Komatsu, M., Dikic, I. and Johansen, T. 2009. A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol. Cell 33, 505-516
Bjørkøy, G., Lamark, T., Pankiv, S., Øvervatn, A., Brech, A. and Johansen T. 2009. Monitoring autophagic degradation of p62/SQSTM1. Meth. Enzymol. 452, 181-197.
Nezis, I. P., Lamark, T., Velentzas, A.D., Rusten, T.E., Bjørkøy, G., Johansen, T., Papassideri, I.S., Stravopodis, D.J., Margaritis, L.H., Stenmark, H. and Brech, A. 2009. Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy. Autophagy 5, 298-302
Kirkin, V., Lamark, T., Johansen, T. and Dikic, I. 2009. NBR1 co-operates with p62 in selective autophagy of ubiquitinated targets. Autophagy 5, 732-733
Lamark, T., Kirkin, V., Dikic, I. and Johansen, T. 2009. NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets. Cell Cycle 8, 1986-1990
Zheng, Y.T., Shahnazari, S., Brech, A., Lamark, T., Johansen, T. and Brumell, J.H. 2009. The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway. J. Immunol. 183, 5909-5916
Pankiv, S., Alemu, E.A., Brech, A., Bruun, J.A., Lamark, T., Øvervatn, A., Bjørkøy, G. and Johansen, T. 2010. FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport. J. Cell Biol. 188, 253-269
Pankiv, S., Lamark, T., Bruun, J.A., Øvervatn, A., Bjørkøy, G. and Johansen, T. 2010. Nucleocytoplasmic shuttling of p62/SQSTM1 and its role in recruitment of nuclear polyubiquitinitated proteins to promyelocytic leukemia bodies. J. Biol. Chem. 285, 5941-5953
Clausen, T. H., Lamark, T., Isakson, P., Finley, K., Bowitz Larsen, K., Brech, A., Øvervatn, A., Stenmark, H., Bjørkøy, G., Simonsen, A. and Johansen, T. 2010. p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy. Autophagy 6, 330-344
Lamark, T. and Johansen, T. 2010. Autophagy: links with the proteasome. Curr. Opin. Cell Biol. 22, 192-198
Ponpuak, M., Davis, A.S., Roberts, E.A., Delgado, M.A., Dinkins, C., Zhao, Z., Virgin, H.W. 4th, Kyei, G.B., Johansen, T., Vergne, I. and Deretic, V. 2010.Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties. Immunity 32, 329-341
Pankiv, S. and Johansen, T. 2010. FYCO1: Linking autophagosomes to microtubule plus end-directing molecular motors. Autophagy 6, 550-552
Jain, A., Lamark, T., Sjøttem, E., Bowitz Larsen, K., Awuh, J.A., Øvervatn, A., McMahon, M., Hayes, J.D. and Johansen, T. 2010. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. J. Biol. Chem., 285, 22576–22591
Dikic, I. , Johansen, T. and Kirkin, V. 2010. Selective autophagy in cancer development and therapy. Cancer Res. 70, 3431-3434
Larsen, K.B., Lamark, T., Øvervatn, A., Harneshaug, I., Johansen, T. and Bjørkøy, G. 2010. A reporter cell system to monitor autophagy based on p62/SQSTM1. Autophagy 6, 784-793
Elvenes, J., Sjøttem, E., Holm, T., Bjørkøy, G. and Johansen, T. 2010. Pax6 localizes to chromatin-rich territories and displays a slow nuclear mobility altered by disease mutations. Cell. Mol. Life Sci. Jun 25. [Epub ahead of print]
Nezis, I.P., Shravage, B.V., Sagona, A.P., Lamark, T., Bjørkøy, G., Johansen, T., Rusten, T.E., Brech, A., Baehrecke, E.H. and Stenmark, H. 2010. Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis. J. Cell. Biol. 190, 523-531
Nezis, I.P., Shravage, B.V., Sagona, A.P., Johansen, T., Baehrecke, E.H. and Stenmark, H. 2010. Autophagy as a trigger for cell death: Autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late in nurse cells during late oogenesis in Drosophila. Autophagy, 6, 1214-1215.
Alemu, E.A., Sjøttem, E., Outzen, H., Larsen, K.B., Holm, T., Bjørkøy, G., Johansen, T.2010. Transforming growth factor-β-inducible early response gene 1 is a novel substrate for atypical protein kinase Cs. Cell. Mol. Life Sci. 68, 1953-1968
Johansen, T. and Lamark, T. 2011. Selective autophagy mediated by autophagic adapter proteins. Autophagy, 7, 279-296.
Hansen, T.E. and Johansen, T. 2011. Following autophagy step by step. BMC Biol. 9, 39. doi:10.1186/1741-7007-9-39
Mostowy, S., Sancho-Shimizu, V., Hamon, M.A., Simeone, R., Brosch, R., Johansen, T. and Cossart P. 2011. p62 and NDP52 Proteins Target Intracytosolic Shigella and Listeria to Different Autophagy Pathways. J. Biol. Chem., 286, 26987-95
Svenning, S., Lamark, T., Krause, K. and Johansen, T. 2011. Plant NBR1 is a selective autophagy substrate and a functional hybrid of the mammalian autophagic adapters NBR1 and p62/SQSTM1. Autophagy, 7, 993-1010
Elvenes, J., Thomassen, E.I.S., Sagen Johnsen, S., Kaino, K., Sjøttem, E. and Johansen, T. 2011. Pax6 Represses Androgen Receptor-Mediated Transactivation by Inhibiting Recruitment of the Coactivator SPBP. PLoS ONE 6, e24659.
Darvekar, S., Johnsen, S.S., Eriksen, A.B., Johansen, T. and Sjøttem, E. 2012. Identification of two independent nucleosome-binding domains in the transcriptional co-activator SPBP. Biochem. J. 442, 65-75
McKnight, N. C., Jeffries, H. B., Alemu, E. A., Saunders, R. E., Howell, M., Johansen, T. and Tooze, S. A. 2012. Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC. EMBO J. doi: 10.1038/emboj.2012.36. [Epub ahead of print]
Sancho, A., Duran, J., García-España, A., Mauvezin, C., Alemu, E.A., Lamark, T., Macias, M.J., Desalle, R., Royo, M., Sala, D., Chicote, J.U., Palacín, M., Johansen, T., and Zorzano, A. 2012. DOR/Tp53inp2 and Tp53inp1 Constitute a Metazoan Gene Family Encoding Dual Regulators of Autophagy and Transcription. PLoS ONE 7, e34034.
Lamark, T. and Johansen, T. 2012. Aggrephagy: Selective Disposal of Protein Aggregates by Macroautophagy. Int. J. Cell Biol. 2012, 736905, 21 pages. doi:10.1155/2012/736905
Aichem, A., Kalveram, B. Spinnenhirn, V., Kluge, K., Catone, N., Johansen, T. and Groettrup, M. 2012. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. J. Cell Sci. 125, 4576-4585
Pilli, M., Arko-Mensah, J., Ponpuak, M., Roberts, E., Master, S., Mandell, M.A., Dupont, N., Ornatowski, W., Jiang, S., Bradfute, S.B., Bruun, J.A., Hansen, T.E., Johansen, T. and Deretic, V. 2012. TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation. Immunity, 37, 223-234
Klionsky, D.J., .....Johansen, T.,.......Lamark, T., ........ and 1267 others. 2012. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8, 445-544.
Kleine, H., Herrmann, A., Lamark, T., Forst, A.H., Verheugd, P., Lüscher-Firzlaff, J., Lippok, B., Feijs, K.L., Herzog, N., Kremmer, E., Johansen, T., Müller-Newen, G. and Luscher B. 2012. Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62. Cell Commun. Signal. 10:28 doi:10.1186/1478-811X-10-28
Alemu, E.A.,, Lamark, T., Torgersen, K.M., Birgisdottir, A.B., Bowitz Larsen, K., Jain, A., Olsvik, H., Øvervatn, A., Kirkin, V. and Johansen, T.2012. ATG8 Family Proteins Act as Scaffolds for Assembly of the ULK Complex: Sequence Requirements for LC3-Interacting Region (LIR) Motifs. J. Biol. Chem. 287, 39275-39290
Deosaran E., Larsen, K.B., Hua, R., Sargent, G., Wang, Y., Kim., S., Lamark, T., Jauregui, M., Law, K., Lippincott-Schwartz, J., Brech, A., Johansen, T. and Kim, P.K. 2013. NBR1 acts as an autophagy receptor for peroxisomes. J. Cell Sci. 126, 939-952
Birgisdottir, A. B., Lamark, T. and Johansen, T. 2013. The LIR motif - crucial for selective autophagy. J. Cell Sci. 126, 3237-3247
Svenning, S. and Johansen, T. 2013. Selective autophagy. Essays Biochem. 55, 79-92
Darvekar, S., Rekdal, C., Johansen, T. and Sjøttem, E. 2013. A Phylogenetic Study of SPBP and RAI1: Evolutionary Conservation of Chromatin Binding Modules. PLoS One 8,e78907. doi: 10.1371/journal.pone.0078907
Darvekar, S., Elvenes, J., Brenne, H. B., Johansen, T. and Sjøttem, E. 2014. SPBP is a Sulforaphane Induced Transcriptional Coactivator of NRF2 Regulating Expression of the Autophagy Receptor p62/SQSTM1. PLoS One 9,e85262. doi: 10.1371/journal.pone.0085262
Rubio, N., Verrax, J., Dewaele, M., Verfaillie, T., Johansen, T., Piette, J. and Agostinis, P. 2014. p38MAPK-regulated induction of p62 and NBR1 after photodynamic therapy promotes autophagic clearance of ubiquitin aggregates and reduces reactive oxygen species levels by supporting Nrf2–antioxidant signaling. Free Radical Biol. Med. 67, 292-303
Rogov, V., Dötsch, V., Johansen, T. and Kirkin, V. 2014. Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy. Mol. Cell 53,167-178
Kalvari, I., Tsompanis, S., Mulakkal, N.C., Osgood, R., Johansen, T., Nezis, I.P. and Promponas, V.J. 2014. iLIR: A web resource for prediction of Atg8-family interacting proteins. Autophagy 10, 913-925
Johansen, T. and Lamark, T. 2014. Selective autophagy goes exclusive. Nat Cell Biol. 16, 395-397
Mandell, M.A., Jain, A., Arko-Mensah, J., Chauhan, S., Kimura, T., Dinkins, C., Silvestri, G., Münch, J., Kirchhoff, F., Simonsen, A., Wei, Y., Levine, B., Johansen, T. and Deretic, V. 2014. TRIM Proteins Regulate Autophagy and Can Target Autophagic Substrates by Direct Recognition. Dev Cell. 30, 394-409
Mandell, M.A., Kimura, T., Jain, A., Johansen, T. and Deretic, V. 2014. TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction. Autophagy 10, 2387-2388
Borel, S., Robert-Hebmann, V., Alfaisal, J., Jain, A., Faure, M, Espert, L., Chaloin, L., Paillart, J.C., Johansen, T. and Biard-Piechaczyk, M. 2015. HIV-1 viral infectivity factor .with light chain 3 and inhibits autophagy. AIDS 29, 275–286
Bertrand M, Petit V, Jain A, Amsellem R, Johansen T, Larue L, Codogno P, Beau I. 2015. SQSTM1/p62 regulates the expression of junctional proteins through epithelial-mesenchymal transition factors. Cell Cycle 14, 364-374
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