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Svetlana Zykova

Førsteamanuensis II
Institutt for klinisk medisin




Arbeider i CRIStin


  • Brovold, Henrik; Lund, Trine; Svistounov, Dmitri; Solbu, Marit Dahl; Jenssen, Trond Geir; Ytrehus, Kirsti; Zykova, Svetlana. Crystallized but not soluble uric acid elicits pro-inflammatory response in short-term whole blood cultures from healthy men. Scientific Reports 2019; Volum 9 (10513). ISSN 2045-2322.s doi: 10.1038/s41598-019-46935-w.

  • Norvik, Jon Viljar; Schirmer, Henrik; Ytrehus, Kirsti; Jenssen, Trond Geir; Zykova, Svetlana; Eggen, Anne Elise; Eriksen, Bjørn Odvar; Solbu, Marit Dahl. Low adiponectin is associated with diastolic dysfunction in women: A cross-sectional study from the Tromsø Study. BMC Cardiovascular Disorders 2017; Volum 17:79. ISSN 1471-2261.s 1 - 10.s doi: 10.1186/s12872-017-0509-2.

  • Norvik, Jon Viljar; Storhaug, Hilde-Merete; Ytrehus, Kirsti; Jenssen, Trond Geir; Zykova, Svetlana; Eriksen, Bjørn Odvar; Solbu, Marit Dahl. Overweight modifies the longitudinal association between uric acid and some components of the metabolic syndrome: The Tromsø Study. BMC Cardiovascular Disorders 2016; Volum 16 (85). ISSN 1471-2261.s doi: 10.1186/s12872-016-0265-8.

  • Solbu, Marit Dahl; Norvik, Jon Viljar; Storhaug, Hilde-Merete; Eriksen, Bjørn Odvar; Melsom, Toralf; Eggen, Anne Elise; Zykova, Svetlana; Kronborg, Jens; Jenssen, Trond Geir. The association between adiponectin, serum uric acid and urinary markers of renal damage in the general population: Cross-sectional data from the Tromsø Study. Kidney and Blood Pressure Research 2016; Volum 41 (5). ISSN 1420-4096.s 623 - 634.s doi: 10.1159/000447931.

  • Zykova, Svetlana; Storhaug, Hilde-Merete; Toft, Ingrid; Chadban, Steven; Jenssen, Trond Geir; White, Sarah L. Cross-sectional analysis of nutrition and serum uric acid in two Caucasian cohorts: the AusDiab Study and the Tromsø study. Nutrition Journal 2015; Volum 14:49. ISSN 1475-2891.s 1 - 11.s doi: 10.1186/s12937-015-0032-1.

  • Zykova, Svetlana; Balandina, K; Vorokhobina, NV; Kuznetsova, A; Engstad, R; Zykova, TA. Macrophage stimulating agent soluble yeast β-1,3/1,6-glucan as a topical treatment of diabetic foot and leg ulcers: A randomized, double blind, placebo-controlled phase II study. Journal of Diabetes Investigation 2014; Volum 5 (4). ISSN 2040-1116.s 392 - 399.s doi: 10.1111/jdi.12165.

  • Svistounov, Dmitri; Oteiza, Ana; Zykova, Svetlana; Sørensen, Karen Kristine; McCourt, Peter Anthony; McLachlan, Andrew J; Mccuskey, Robert Scott; Smedsrød, Bård. Hepatic disposal of advanced glycation end products during maturation and aging. Experimental Gerontology 2013; Volum 48 (6). ISSN 0531-5565.s 549 - 556.s doi: 10.1016/j.exger.2013.03.005.

  • Svistounov, Dmitri; Cogger, V.C.; Warren, Alessandra; Zykova, Svetlana; Melvin, Rachel; Solon-Biet, S; O'Reilly, JN; McMahon, AC; Ballard, JW; de Cabo, R; Le Couteur, David G; Lebel, M. Liver Aging and Pseudocapillarization in a Werner Syndrome Mouse Model. The journals of gerontology. Series A, Biological sciences and medical sciences 2013. ISSN 1079-5006.

  • Storhaug, Hilde-Merete; Norvik, Jon Viljar; Toft, Ingrid; Eriksen, Bjørn Odvar; Løchen, Maja-Lisa; Zykova, Svetlana; Solbu, Marit Dahl; White, Sarah; Chadban, S; Jenssen, Trond Geir. Uric acid is a risk factor for ischemic stroke and all-cause mortality in the general population: a gender specific analysis from The Tromsø Study. BMC Cardiovascular Disorders 2013; Volum 13. ISSN 1471-2261.s doi: 10.1186/1471-2261-13-115.

  • Pettersen, ingvild; Baryawno, Ninib; Abel, Frida; Bakkelund, wenche helen; Zykova, Svetlana; Winberg, Jan-Olof; Moens, Ugo; Rasmuson, Agnes; Kogner, Per; Johnsen, John Inge; Sveinbjørnsson, Baldur. Expression of TWEAK/Fn14 in neuroblastoma: Implications in tumorigenesis. International Journal of Oncology 2013; Volum 42 (4). ISSN 1019-6439.s 1239 - 1248.s doi: 10.3892/ijo.2013.1800.

  • Svistounov, Dmitri; Warren, Alessandra; McNerney, Gregory P; Owen, Dylan M.; Zencak, Dusan; Zykova, Svetlana; Crane, Harry; Huser, Thomas; Quinn, Ronald J.; Smedsrød, Bård; Le Couteur, David G; Cogger, Victoria C. The Relationship between Fenestrations, Sieve Plates and Rafts in Liver Sinusoidal Endothelial Cells. PLOS ONE 2012; Volum 7 (9). ISSN 1932-6203.s doi: 10.1371/journal.pone.0046134.

  • Svistounov, Dmitri; Zykova, Svetlana; Cogger, Victoria C; Warren, Alessandra; Fraser, Robin; Smedsrød, Bård; Mccuskey, Robert Scott; Le Couteur, David G. Pseudocapillarization and the aging liver. Springer Science+Business Media B.V. 2011 ISBN 978-1-4419-8326-8.s 41 - 50.

  • Zykova, Svetlana; Tveita, Anders; Rekvik, Ole Petter. Renal Dnase1 Enzyme Activity and Protein Expression Is Selectively Shut Down in Murine and Human Membranoproliferative Lupus Nephritis. PLOS ONE 2010; Volum 5 (8). ISSN 1932-6203.s e12096 - .s doi: 10.1371/journal.pone.0012096.

  • Seredkina, Natalya; Zykova, Svetlana; Rekvik, Ole Petter. Progression of Murine Lupus Nephritis Is Linked to Acquired Renal Dnase1 Deficiency and Not to Up-Regulated Apoptosis. American Journal of Pathology 2009; Volum 175 (1). ISSN 0002-9440.s 97 - 106.s doi: 10.2353/ajpath.2009.080943.

  • Tveita, Anders Aune; Ninomiya, Y; Sado, Y; Rekvik, Ole Petter; Zykova, Svetlana. Development of lupus nephritis is associated with qualitative changes in the glomerular collagen IV matrix composition. Lupus 2009; Volum 18 (4). ISSN 0961-2033.s 355 - 360.s doi: 10.1177/0961203308100842.

  • Tveita, Anders Aune; Rekvik, Ole Petter; Zykova, Svetlana. Increased glomerular matrix metalloproteinase activity in murine lupus nephritis. Kidney International 2008; Volum 74 (9). ISSN 0085-2538.s 1150 - 1158.s doi: 10.1038/ki.2008.308.

  • Tveita, Anders Aune; Rekvik, Ole Petter; Zykova, Svetlana. Glomerular matrix metalloproteinases and their regulators in the pathogenesis of lupus nephritis. Arthritis Research & Therapy 2008; Volum 10 (6). ISSN 1478-6354.s 229 - 236.s doi: 10.1186/ar2532.

  • Martin, armas maria montserrat; Zykova, Svetlana; Smedsrød, Bård. Effects of CpG-oligonucleotides, poly I:C and LPS on Atlantic cod scavenger endothelial cells (SEC). Developmental and Comparative Immunology 2008; Volum 32 (2). ISSN 0145-305X.

  • Martin, armas maria montserrat; Zykova, Svetlana; Smedsrød, Bård. Effects of CpG-oligonucteotides, poly I : C and LPS on Atlantic cod scavenger endothelial cells (SEC). Developmental and Comparative Immunology 2008; Volum 32. ISSN 0145-305X.s doi: 10.1016/j.dci.2007.04.008.

  • Zykova, Svetlana; Seredkina, Natalya; Benjaminsen, Jørgen; Rekvik, Ole Petter. Reduced fragmentation of apoptotic chromatin is associated with nephritis in lupus-prone (NZB x NZW)F-1 mice. Arthritis and Rheumatism 2008; Volum 58. ISSN 0004-3591.s 813 - 825.s doi: 10.1002/art.23276.

  • Zykova, Svetlana; Seredkina, Natalya; Rekvik, Ole Petter. Glomerular targets for autoantibodies in lupus nephritis - An apoptotic origin. Annals of the New York Academy of Sciences 2007; Volum 1108. ISSN 0077-8923.s 1 - 10.s doi: 10.1196/annals.1422.001.

  • Berdal, Margrete; Appelbom, Hege; Eikrem, Jorunn; Lund, Åse; Zykova, Svetlana; Busund, Lill-Tove Rasmussen; Seljelid, Rolf; Jenssen, Trond Geir. Aminated beta-1,3-D-glucan improves wound healing in diabetic db/db mice. Wound Repair and Regeneration 2007; Volum 15. ISSN 1067-1927.s 825 - 832.s doi: 10.1111/j.1524-475X.2007.00286.x.

  • Zykova, Svetlana; Svartberg, Johan; Seljelid, Rolf; Iversen, Hege; Lund, A; Svistounov, Dmitri; Jenssen, Trond Geir. Release of TNF-alpha from in vitro-stimulated monocytes is negatively associated with serum levels of apolipoprotein B in patients with type 2 diabetes. Scandinavian Journal of Immunology 2004; Volum 60 (5). ISSN 0300-9475.s 535 - 542.

  • Svistounov, Dmitri; Berg, Tore J.; McCourt, Peter Anthony; Zykova, Svetlana; Elvevold, Kjetil Helge; Nagai, Ryoji; Horiuchi, Seikoh; Smedsrød, Bård. Lack of recognition of N-epsilon-(carboxymethyl)lysine by the mouse liver reticulo-endothelial system: implications for pathophysiology. Biochemical and Biophysical Research Communications - BBRC 2003; Volum 309. ISSN 0006-291X.s 786 - 791.

  • Zykova, Svetlana; Jenssen, Trond Geir; Berdal, Margrete; Olsen, Randi; Myklebust, R; Seljelid, Rolf. Altered cytokine and nitric oxide secretion in vitro by macrophages from diabetic type II-like db/db mice. Diabetes 2000; Volum 49 (9). ISSN 0012-1797.s 1451 - 1458.

  • Nymo, Stig; Kuklin, Vladimir; Zykova, Svetlana; Bjertnaes, Lars J.. RECOMBINANT HUMAN ACTIVATED PROTEIN C HAS A GLOBAL MODULATING EFFECT ON THE INFLAMMATORY RESPONSE IN MURINE SEPSIS. Intensive Care Medicine 2010; Volum 36. ISSN 0342-4642.s S193 - S193.

  • Seredkina, Natalya; Zykova, Svetlana; Rekvig, Ole Petter. Analysis of apoptotic activity in lupus nephritis. PhD school in Molecular and Structural Biology Open Day 2007-09-21 - 2007-09-21 2007.

  • Zykova, Svetlana; Rekvik, Ole Petter. Ekectrophoretic analysis of DNA from kidneys of (NZBxNZW)F1 mice. 5th International Congress of Autoimmunity 2006-11-23 - 2006-12-03 2006.

  • Zykova, Svetlana; JAKOBSEN, SIW ELLEN. Kommer langveis fra og trives i Tromsø. 2005.

  • Kuklin, Vladimir; Zykova, Svetlana; Gruber, Franz; Bjertnæs, Lars J.. The influence of tezosentan and activated protein C on expression of mRNA for endothelin-1 and endothelin-1 receptors in septicemic rats. Norsk anestesiologisk forenings høstmøte 2004-10-20 - 2004-10-23 2004.

  • Zykova, Svetlana; Jenssen, Trond Geir; Svistounov, Dmitri; Eikrem, jorunn; Seljelid, Rolf. MECHANISMS FOR THE IMPAIRED IN VITRO RELEASE OF TNF-a FROM MACROPHAGES IN DIABETIC TYPE 2-LIKE DB/DB MOUSE. Scandinavian Society for the Study of Diabetes 2003-04-04 - 2003-04-06 2003.

  • Zykova, Svetlana; Svartberg, Johan; Seljelid, Rolf; Jenssen, Trond Geir. RELEASE OF TNF-a FROM IN VITRO STIMULATED MONOCYTES IS NEGATIVELY ASSOCIATED WITH SERUM LEVELS OF APOLIPOPROTEIN B IN TYPE 2 DIABETES. Scandinavian Society for the Study of Diabetes 2003-04-04 - 2003-04-06 2003.

  • Zykova, Svetlana; Seljelid, Rolf; Jenssen, Trond Geir. Studies on macrophage dysfunction in type 2 diabetes. 2002 ISBN 82-7589-131-0.

  • Berdal, Margrete; Zykova, Svetlana; Seljelid, Rolf; Jenssen, Trond Geir. Aminoguanidine does not improve wound healing in diabetes. 36th annual meeting of the Scandinavian Society for the Study of Diabetes 2001-05-25 - 2001-05-27 2001.

  • Berdal, Margrete; Zykova, Svetlana N.; Seljelid, Rolf; Jenssen, Trond Geir. The effects of aminoguanidine and beta-1,3-D polyglucose on wound healing in diabetes mellitus. The 37th annual meeting of the European Association for the Study of Diabetes 2001-09-09 - 2001-09-13 2001.