Elin

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Elin Synnøve Mortensen

Professor og forskningsgruppeleder RAMP
Institutt for medisinsk biologi




Arbeider i CRIStin


  • Lofterød, Trygve; Mortensen, Elin Synnøve; Nalwoga, Hawa; Wilsgaard, Tom; Frydenberg, Hanne; Risberg, Terje; Eggen, Anne Elise; McTiernan, Anne; Aziz, Sura Mohammed; Wist, Erik; Stensvold, Andreas; Reitan, Jon Brinchmann; Akslen, Lars A.; Thune, Inger. Impact of pre-diagnostic triglycerides and HDL-cholesterol on breast cancer recurrence and survival by breast cancer subtypes. BMC Cancer 2018; Volum 18 (654). ISSN 1471-2407.s doi: 10.1186/s12885-018-4568-2.

  • Figenschau, Stine; Knutsen, Erik; Urbarova, Ilona; Fenton, Christopher Graham; Elston, Bryan; Perander, Maria; Mortensen, Elin Synnøve; Fenton, Kristin Andreassen. ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes. Scientific Reports 2018; Volum 8:11720. ISSN 2045-2322.s 1 - 12.s doi: 10.1038/s41598-018-29604-2.

  • Frydenberg, Hanne; Thune, Inger; Lofterød, Trygve; Mortensen, Elin Synnøve; Eggen, Anne Elise; Risberg, Terje; Wist, Erik; Flote, Vidar Gordon; Furberg, Anne-Sofie; Wilsgaard, Tom; Akslen, Lars A.; McTiernan, Anne. Pre-diagnostic high-sensitive C-reactive protein and breast cancer risk, recurrence, and survival. Breast Cancer Research and Treatment 2016; Volum 155 (2). ISSN 0167-6806.s 345 - 354.s doi: 10.1007/s10549-015-3671-1.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve; Skjeldestad, Finn Egil. Primary cervical cancer screening with an HPV mRNA test: a prospective cohort study. (fulltekst) BMJ Open 2016; Volum 6. ISSN 2044-6055.s doi: 10.1136/bmjopen-2016-011981.

  • Figenschau, Stine Linn; Fismen, Silje; Fenton, Kristin Andreassen; Fenton, Christopher Graham; Mortensen, Elin Synnøve. Tertiary lymphoid structures are associated with higher tumor grade in primary operable breast cancer patients. BMC Cancer 2015; Volum 15:101. ISSN 1471-2407.s doi: 10.1186/s12885-015-1116-1.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve; Skjeldestad, Finn Egil. HPV mRNA is more specific than HPV DNA in triage of women with minor cervical lesions. (fulltekst) PLOS ONE 2014; Volum 9 (11). ISSN 1932-6203.s doi: 10.1371/journal.pone.0112934.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve; Skjeldestad, Finn Egil. HPV mRNA testing in triage of women with ASC-US cytology may reduce the time for CIN2+ diagnosis compared with repeat cytology. Current pharmaceutical design 2013; Volum 19 (8). ISSN 1381-6128.s 1401 - 1405.s doi: 10.2174/138161213804805487.

  • Seredkina, Natalya; van der Vlag, Johan; Berden, Jo; Mortensen, Elin Synnøve; Rekvig, Ole Petter. Lupus Nephritis: Enigmas, Conflicting Models and an Emerging Concept. Molecular medicine (Cambridge, Mass. Print) 2013; Volum 19. ISSN 1076-1551.s 161 - 169.s doi: 10.2119/molmed.2013.00010.

  • Fismen, Silje; Thiyagarajan, Dhivya; Seredkina, Natalya; Nielsen, Henrik; Jacobsen, Søren; Elung-Jensen, Thomas; Kamper, Anne-Lise; Johansen, Steinar; Mortensen, Elin Synnøve; Rekvig, Ole Petter. Impact of the Tumor Necrosis Factor Receptor-Associated Protein 1 (Trap1) on Renal DNaseI Shutdown and on Progression of Murine and Human Lupus Nephritis. American Journal of Pathology 2013; Volum 182 (3). ISSN 0002-9440.s 688 - 700.s doi: 10.1016/j.ajpath.2012.11.013.

  • Rekvig, Ole Petter; Mortensen, Elin Synnøve. Immunity and autoimmunity to dsDNA and chromatin - the role of immunogenic DNA-binding proteins and nuclease deficiencies. Autoimmunity 2012; Volum 45 (8). ISSN 0891-6934.s 588 - 592.s doi: 10.3109/08916934.2012.719954.

  • Thiyagarajan, Dhivya; Fismen, Silje; Seredkina, Natalya; Jacobsen, Søren; Elung-Jensen, Thomas; Kamper, Anne-Lise; Fenton, Christopher Graham; Rekvig, Ole Petter; Mortensen, Elin Synnøve. Silencing of Renal DNaseI in Murine Lupus Nephritis Imposes Exposure of Large Chromatin Fragments and Activation of Toll Like Receptors and the Clec4e. PLOS ONE 2012; Volum 7 (3). ISSN 1932-6203.s doi: 10.1371/journal.pone.0034080.

  • Rekvig, Ole Petter; Putterman, Chaim; Casu, Cinzia; Gao, Hua-Xin; Ghirardello, Anna; Mortensen, Elin Synnøve; Tincani, Angela; Doria, Andrea. Autoantibodies in lupus: Culprits or passive bystanders?. Autoimmunity Reviews 2012; Volum 11 (8). ISSN 1568-9972.s 596 - 603.s doi: 10.1016/j.autrev.2011.10.021.

  • Fismen, Silje; Mortensen, Elin; Rekvig, Ole Petter. Nuclease deficiencies promote end-stage lupus nephritis but not nephritogenic autoimmunity in (NZBxNZW) F1 mice. Immunology and Cell Biology 2011; Volum 89 (1). ISSN 0818-9641.s 90 - 99.s doi: 10.1038/icb.2010.75.

  • Sørbye, Sveinung Wergeland; Arbyn, Marc; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve. HPV E6/E7 mRNA Testing Is More Specific than Cytology in Post-Colposcopy Follow-Up of Women with Negative Cervical Biopsy. PLOS ONE 2011; Volum 6 (10). ISSN 1932-6203.s doi: 10.1371/journal.pone.0026022.

  • Sørbye, Sveinung Wergeland; Arbyn, Marc; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin. Triage of Women with Low-Grade Cervical Lesions - HPV mRNA Testing versus Repeat Cytology. PLOS ONE 2011; Volum 6 (8). ISSN 1932-6203.s doi: 10.1371/journal.pone.0024083.

  • Hedberg, Annica; Fismen, Silje; Fenton, Kristin Andreassen; Fenton, Christopher Graham; Østerud, Bjarne; Mortensen, Elin; Rekvig, Ole Petter. Heparin Exerts a Dual Effect on Murine Lupus Nephritis by Enhancing Enzymatic Chromatin Degradation and Preventing Chromatin Binding in Glomerular Membranes. Arthritis and Rheumatism 2011; Volum 63 (4). ISSN 0004-3591.s 1065 - 1075.s doi: 10.1002/art.30211.

  • Hedberg, Annica; Mortensen, Elin; Rekvig, Ole Petter. Chromatin as a target antigen in human and murine lupus nephritis. Arthritis Research & Therapy 2011; Volum 13 (2). ISSN 1478-6354.s doi: 10.1186/ar3281.

  • Mortensen, Kim Erlend; Conley, LN; Nygård, Ingvild; Sørensen, Peter; Mortensen, Elin; Bendixen, C; Revhaug, Arthur. Increased sinusoidal flow is not the primary stimulus to liver regeneration. Comparative Hepatology 2010; Volum 9 (2). ISSN 1476-5926.s doi: 10.1186/1476-5926-9-2.

  • Fismen, Silje; Mortensen, Elin; Rekvig, Ole Petter. Nuclease deficiencies promote end-stage lupus nephritis but not nephritogenic autoimmunity in (NZB x NZW) F1 mice. Immunology and Cell Biology 2010; Volum 89. ISSN 0818-9641.s 90 - 99.s doi: 10.1038/icb.2010.75.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin. HPV mRNA test in women with minor cervical lesions: Experience of the University Hospital of North Norway. Journal of Virological Methods 2010; Volum 169 (1). ISSN 0166-0934.s 219 - 222.s doi: 10.1016/j.jviromet.2010.07.011.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin. Triage of Women with Minor Cervical Lesions: Data Suggesting a "Test and Treat" Approach for HPV E6/E7 mRNA Testing. PLOS ONE 2010; Volum 5 (9). ISSN 1932-6203.s doi: 10.1371/journal.pone.0012724.

  • Hedberg, Annica; Fismen, Silje; Fenton, Kristin Andreassen; Mortensen, Elin; Rekvig, Ole Petter. Deposition of chromatin-IgG complexes in skin of nephritic MRL-lpr/lpr mice is associated with increased local matrix metalloprotease activities. Experimental Dermatology 2010; Volum 19 (8). ISSN 0906-6705.s E265 - E274.s doi: 10.1111/j.1600-0625.2010.01064.x.

  • Fenton, Kristin Andreassen; Fismen, Silje; Hedberg, Annica; Seredkina, Natalya; Fenton, Christopher Graham; Mortensen, Elin; Rekvik, Ole Petter. Anti-dsDNA Antibodies Promote Initiation, and Acquired Loss of Renal Dnase1 Promotes Progression of Lupus Nephritis in Autoimmune (NZBxNZW)F1 mice. PLOS ONE 2009; Volum 4 (12). ISSN 1932-6203.s doi: 10.1371/journal.pone.0008474.

  • Mortensen, Elin Synnøve; Kearney, Michael Shelley. Meconium Aspiration in the Midtrimester Fetus: An Autopsy Study. Pediatric and Developmental Pathology 2009; Volum 12 (6). ISSN 1093-5266.s 438 - 442.s doi: 10.2350/08-05-0464.1.

  • Mortensen, Elin; Rekvik, Ole Petter. Nephritogenic Potential of Anti-DNA Antibodies against Necrotic Nucleosomes. Journal of the American Society of Nephrology 2009; Volum 20 (4). ISSN 1046-6673.s 696 - 704.s doi: 10.1681/ASN.2008010112.

  • Fismen, Silje; Hedberg, Annica; Fenton, Kristin Andreassen; Jacobsen, S; Krarup, E; Kamper, AL; Rekvik, Ole Petter; Mortensen, Elin. Circulating chromatin-anti-chromatin antibody complexes bind with high affinity to dermo-epidermal structures in murine and human lupus nephritis. Lupus 2009; Volum 18 (7). ISSN 0961-2033.s 597 - 607.s doi: 10.1177/0961203308100512.

  • Mortensen, Elin; Rognum, TO; Straume, Bjørn; Jørgensen, Leif. Frequency of acute asymptomatic myocardial infarction and an estimate of infarct age in cases of abrupt sudden death observed in a forensic autopsy material. Journal of Cellular and Molecular Medicine 2008; Volum 12 (5B). ISSN 1582-1838.s 2119 - 2129.s doi: 10.1111/j.1582-4934.2008.00247.x.

  • Mortensen, Elin; Fenton, Kristin Andreassen; Rekvik, Ole Petter. Lupus nephritis - The central role of nucleosomes revealed. American Journal of Pathology 2008; Volum 172. ISSN 0002-9440.s 275 - 283.s doi: 10.2353/ajpath.2008.070563.

  • Bendiksen, signy; Mortensen, Elin; Olsen, randi; Fenton, Kristin Andreassen; Kalaaji, manar; Jørgensen, Leif; Rekvik, Ole Petter. Glomerular expression of large polyomavirus T antigen in binary tet-off regulated transgenic mice induces apoptosis, release of chromatin and initiates a lupus-like nephritis. Molecular Immunology 2008; Volum 45 (3). ISSN 0161-5890.s 728 - 729.s doi: 10.1016/j.molimm.2007.07.010.

  • Kalaaji, manar; Fenton, Kristin Andreassen; Mortensen, Elin; Olsen, randi; Sturfelt, G; Alm, P; Rekvik, Ole Petter. Glomerular apoptotic nucleosomes are central target structures for nephritogenic antibodies in human SLE nephritis. Kidney International 2007; Volum 71. ISSN 0085-2538.s doi: 10.1038/sj.ki.5002133.

  • Fismen, Silje; Rekvik, Ole Petter; Mortensen, Elin. Pathogenesis of SLE dermatitis - a reflection of the process in SLE nephritis?. Current Rheumatology Reviews 2007. ISSN 1573-3971.

  • Mortensen, Elin; Rognurn, Torleiv O; Rognum, Torleiv Ole; Straume, Bjørn; Jørgensen, Leif; Jorgensen, L. Evidence at autopsy of spasm in the distal right coronary artery in persons with coronary heart disease dying suddenly. Cardiovascular pathology 2007; Volum 16. ISSN 1054-8807.s 336 - 343.s doi: 10.1016/j.carpath.2007.05.006.

  • Kalaaji, Manar; Mortensen, Elin; Jørgensen, Leif; Olsen, Randi; Rekvik, Ole Petter. Nephritogenic lupus antibodies recognize glomerular basement membrane-associated chromatin fragments released from apoptotic intraglomerular cells. American Journal of Pathology 2006; Volum 168. ISSN 0002-9440.s 1779 - 1792.

  • Fenton, Kristin Andreassen; Figenschau, Stine; Mortensen, Elin Synnøve. ICAM1 er uttrykt i trippel negative brystkreftceller og vev. Best Practice Nordic Onkologi/Hematologi 2018; Volum 8 (40).s 46 - 48.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin; Skjeldestad, Finn Egil. HPV mRNA testing is more specific than HPV DNA testing in triage of women with minor cervial lesions. Eurogin 2013 (omtale) 2013-11-03 - 2013-11-06 2013.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Mortensen, Elin Synnøve; Gutteberg, Tore Jarl. HPV-test i forebygging av livmorhalskreft. (fulltekst) Tidsskrift for Den norske legeforening 2012; Volum 132 (4). ISSN 0029-2001.s 396 - 397.s doi: 10.4045/tidsskr.11.0976.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Mortensen, Elin Synnøve; Gutteberg, Tore Jarl; Skjeldestad, Finn Egil. HPV mRNA and cytology cotesting in primary cervical caner screening by age. IPV 2012 2012-11-30 - 2012-12-06 2012.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Mortensen, Elin Synnøve; Gutteberg, Tore Jarl; Skjeldestad, Finn Egil. Post-colposcopy follow-up of women with negative cervical biopsy - a prospecitve study. Eurogin 2012 2012-07-08 - 2012-07-11 2012.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve. HPV-testing og livmorhalskreft. (fulltekst) Tidsskrift for Den norske legeforening 2011; Volum 3 (131). ISSN 0029-2001.s 333 - 333.s doi: 10.4045/tidsskr.10.1426.

  • Mortensen, Elin Synnøve; Fismen, Silje. Forsvarlig bruk av HPV-test. (fulltekst) Dagens medisin 2011. ISSN 1501-4290.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve. Redegjør for HPV-resultater. (fulltekst) Dagens medisin 2011. ISSN 1501-4290.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve; Skjeldestad, Finn Egil. HPV mRNA testing - longterm follow-up. EUROGIN 2011-05-08 - 2011-05-11 2011.

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve; Skjeldestad, Finn Egil. HPV mRNA test in primry screening of women 20-34 years. The 27th international Papillomavirus conference 2011-09-17 - 2011-09-22 2011.

  • Mortensen, Elin. LUPUS NEPHRITIS, AN ACQUIRED ERROR OF CHROMATIN METABOLISM IN AUTOIMMUNE (NZBXNZW)F1 MICE. Clinical and Experimental Rheumatology 2011; Volum 29 (1). ISSN 0392-856X.s 161 - 161.

  • Mortensen, Elin; Rognum, TO; Straume, Bjørn; Jørgensen, Leif. Frequency and Time of Onset of Acute Myocardial Infarction in Sudden unexpected Deaths in a Forensic Autopsy Material. ISTH 2007 XXIst Congress of the International Society on Thrombosis and Haemostasis 53rd Annual SSC Meeting 2007-07-06 - 2007-07-12 2007.

  • Mortensen, Elin; Rognum, TO; Straume, Bjørn; Jørgensen, Leif. Evidence at autopsy of spasm in the right distal coronary artery in cases of coronary heart disease with sudden death. Atherosclerosis Supplements 2007; Volum 8. ISSN 1567-5688.

  • Mortensen, Elin; Rognum, Torleiv; Straume, Bjørn; Jørgensen, Leif. Cause, frequency and time of onset of asymptomatic acute myocardial infarction in abrupt unexpected deaths in a forensic autopsy material. Virchows Archiv 2007; Volum 451. ISSN 0945-6317.s 487 - 487.

  • Mortensen, Elin. FISH and DNA quality. Analysis on tissue form two different laboratories. Nordic Pathology User Meeting & Sympposium 2005-11-10 - 2005-11-11 2005.

  • Mortensen, Elin. Use of rapid CK on frozen sections. Nordic Pathology User Meeting & Symposium 2005-11-10 - 2005-11-11 2005.

  • Mortensen, Elin; Hansen, L; Bjurstam, Nils; Klenow, S; Frantzen, Jan-Ole; Paulssen, Ruth H. Imprint of core biopsies as a reliable diagnostic tool in breast cancer and possible usefullness for research purposes. Breast Cancer Research 2005; Volum 7. ISSN 1465-5411.s 33 - .

  • Mortensen, Elin; Hansen, L; Frantsen, JO; Klenow, S; Bjurstam, N; Paulssen, RH. Imprint as a reliable diagnostic tool in breast cancer and possible usefulness for research purpose. Breast Cancer Research 2005; Volum 7. ISSN 1465-5411.

  • Mortensen, Elin; Hansen, L; Frantsen, JO; Klenow, S; Bjurstam, N; Paulsen, RH. Imprint as a reliable diagnostic tool in breast cancer and possible usefulness for research purposes. Breast Cancer Research 2005; Volum 7. ISSN 1465-5411.s 3 - 7.

  • Publikasjoner utenfor Cristin


    Publikasjonsliste 2007-2011
    .   

    1. Kalaaji M, Fenton K, Mortensen E, Olsen R, Sturfelt, G, Alm P, Rekvig OP. Glomerular apoptotic nucleosomes are central target structures for nephritogenic antibodies in human SLE nephritis. Kidney Int., 2007,Apr;71(7):664-72
    2. Fismen S., Rekvig OP., Mortensen ES., Pathogenesis of SLE dermatitis - A Reflection of the Process in SLE nephritis? Current Rheumatology Reviews, 2007, 3, 159-65
    3. Mortensen ES, Rognum TO, Straume B, Jørgensen L. Evidence at autopsy of spasm in the distal right coronary artery in persons with coronary heart disease dying suddenly.  Cardiovasc Pathol. 2007 Nov-Dec;16(6):336-43. Epub 2007 Jul 25
    4. Mortensen ES, Fenton KA, Rekvig OP. Lupus nephritis: the central role of nucleosomes revealed. Am J Pathol. 2008 Feb;172(2):275-83. Epub 2008 Jan 10.
    5. Mortensen ES, Rognum TO, Straume B, Jørgensen L. Frequency of acute asymptomatic myocardial infarction and an estimate of infarct age in cases of abrupt sudden death observed in a forensic autopsy material. J Cell Mol Med. 2008 Oct;12(5B):2119-29. Epub 2008 Jan 19.
    6. BendiksenS, Mortensen ES, Olsen R, Fenton KA, Kalaaji M, Jørgensen L, Rekvig OP. Glomerular expression of large polyomavirus T antigen in binary tet-off regulated transgenic mice induces apoptosis, release of chromatin and initiates a lupus-like nephritis. Mol Immunol. 2008;45:728-39.
    7. Mortensen E, and Rekvig OP. Nephritogenic potential of anti-DNA antibodies against necrotic nucleosomes. Invited Manuscript. Review J Am Soc Nephrol, 20(4):696-704, 2009.
    8. Fenton K, Fismen S, Hedberg A, Seredkina N, Fenton C, Mortensen ES, Rekvig OP. Anti-dsDNA antibodies promote initiation, and acquired loss of renal Dnase1 promotes progression of lupus nephritis in autoimmune (NZBxNZW)F1 mice. PLoS One. 2009, 29;4(12):e8474
    9. Fismen S, Hedberg A, Fenton K, Jacobsen S, Krarup E, Kamper A, Rekvig O, Mortensen E. Circulating chromatin-anti-chromatin antibody complexes bind with high affinity to dermo-epidermal structures in murine and human lupus nephritis. 2009. Lupus 18(7): 597-607
    10. Mortensen ES, Kearney M. Meconium aspiration in mid trimester fetus:             an autopsy study. Pediatr Dev Pathol, 2009, Nov.Dec;12(6):438-42
    11. Fismen S, Mortensen ES, Rekvig. OP. Nuclease deficiencies promotes end-stage lupus nephritis but not nephritogenic autoimmunity. Review, Immunol Cell Biol, 2010 June 15
    12. Hedberg A,  Fismen S, Fenton  KA, Mortensen ES, Rekvig OP. Deposition of chromatin-IgG complexes in skin of nephritic MRL-lpr/lpr mice is associated with increased local matrix metalloprotease activities. Exp Dermatol. 2010, Aug 19(8):e265-74
    13. Hedberg A, Fismen S, Fenton KA, Østerud B, Mortensen ES, Rekvig OP. Heparin exerts dual effect on murine lupus nephritis by enhancing enzymatic chromatin degradation and preventing chromatin binding in glomerular membranes. Arthritis Rheum, 2011, Apr;63(4):1065-75.doi:10.1002/art.30211
    14. Mortensen KE, Conley LN, Nygaard I, Soerensen P, Mortensen E, Bendixen C, Revhaug A. Increased sinusoidal flow is not the primary stimulus to liver regeneration.Comp Hepatol., 2010, 20;9:2  
    15. Wergeland SS, Fismen S, Gutteberg TJ, Mortensen E.  HPV mRNA test in women with minor cervical lesions:  experiences from the University Hospital of North Norway. Journal of Virological Methods. 2010 oct;169(1)219-22 Epub 2010 Jul 16. PMID:20638416
    16. Wergeland SS, Fismen S, Gutteberg TJ, Mortensen E. Triage of Women with Minor Cervical Lesions: Data Suggesting a “Test and Treat” Approach for HPV E6/E7 mRNA Testing. Plos One 2010 sept 13;5(9):e12724, PMID:20856930
    17. Hedberg A, Mortensen ES, Rekvig OP. Chromatin as a target antigen in human and murine lupus nephritis.  Arthritis Res Ther. 2011, apr 18;13(2):214 (epub ahead of print).
    18. Sørbye SW, Arbyn M, Fismen S, Gutteberg TJ, Mortensen ES Triage of Women with Low-Grade Cervical Lesions - HPV mRNA Testing versus Repeat Cytology. PLoS ONE 2011 6(8): e24083. doi:10.1371/journal.pone.0024083
    19. Sørbye SW, Arbyn M, Fismen S, Gutteberg T, Mortensen ES. Follow-up of women with negative cervical biopsy - HPV E6/E7 mRNA testing versus cytology. PLoS One. 2011 okt.