Ansatt---Tor-Stuge
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Tor Brynjar Stuge

Scientist and lecturer, Immunology
Institutt for medisinsk biologi




Forskningsinteresser

Cellular Immunology

Interplay between T cells and B cells in alloimmune responses

Fetal and Neonatal Alloimmune Thrombocytopenia

CV

Born: 1963. Gjøvik, Norway.

Citizenship: Norwegian.

Education:

August 1985 – February 1992:

Norwegian College of Fishery Science, University of Tromsø, Norway.

 - Master's degree in Marine Biochemistry (February 1992)

March 1992 – February 1998:

Dept. of Microbiology, University of Mississippi Medical Center, Jackson, Mississippi, USA.

 - PhD degree in Immunology (May 1998)

Professional Experience:

February 1998 – February 2000:

Dept. of Microbiology, University of MississippiMedical Center, Jackson, Mississippi, USA.

 - Postdoctoral Fellow.

March 2000 – July 2006:

Division of Hematology, Stanford University School of Medicine, Palo Alto, California, USA.

 - Postdoctoral Fellow/Research Associate.

September 2006 – present:                                                                                                  

Immunology Research Group, Department of Medical Biology, University of Tromsø – The Arctic University of Norway, Tromsø, Norway.

 - Professor since September 2011.

 - Leader, Immunology Research Group since August 2013.

 

Résumé:

I am a native of Norway and currently a professor at the University of Tromsø - The Arctic University of Norway. My current research focus is immune responses associated with Fetal and Neonatal Alloimmune Thrombocytopenia - a condition caused by maternal antibodies reactive with fetal platelets - and especially the nature of maternal T cell responses that leads to this condition. Earlier in my career, I worked with T cell responses in cancer patients and in fish

 

Mentorship:

I have served as principal mentor for 4 doctoral students: Maria Therese Ahlen, PhD, graduated 2011; Mariana Eksteen, PhD, graduated 2015; Gøril Heide, MD, will defend her PhD thesis in 2018; Ida Løken Killie will defend her PhD thesis 2018. In addition, I have served as co-mentor for 3 PhD students. I have also mentored 4 master's degree students and two "Forskerlinje" students ("Forskerlinje" is a medical school research graduate program). I have also mentored a number of medical students and hosted six visiting international students involved in research assignments in our laboratory. I was also a member of the PhD committee for Carina Bauerlein, a student in the research group of Dr. Andreas Beilhack at the University of Wurzburg, Germany. Graduated summer 2013.                            

 

Teaching:

I have been teaching continuously since fall 2006. I lecture for students in medical, dental, and graduate schools. I also teach by leading discussion groups and in laboratory classes. Mainly, I teach immunology, although I also teach a class in the philosophy of science. On average, I teach about 90 hours per year. In addition, I am responsible for arranging and coordinating several different courses and I am a permanent member of several different exam commissions. I also serve as the immunology teaching coordinator for the Institute of Medical Biology.

Patents/Patent applications:

1.         Methods and compositions for producing target cell reactive lymphocytes in a subject.      Inventors: Peter P. Lee and Tor B. Stuge (2006). Pub. nr: WO2006020319 A3

2.         Treatment of neonatal alloimmune thrombocytopenia. Pub. Nr: WO 2014131856 A1

            Inventors: Tor B Stuge, Bjørn R Skogen, Anne Husebekk, Maria Therese Ahlen (2014)

3.         Antibodies against HPA-1a. Pub. nr: WO 2015150417 A1

             Inventors: Tor Brynjar Stuge, Mariana Eksteen, Heidi Tiller, Terje Michaelsen, Øistein Ihle, Anne   Husebekk, Bjørn Ragnar Skogen (2015)

Arbeider i CRIStin


  • Saris, Anno; Peyron, Ivan; Van Der Meer, Pieter F.; Stuge, Tor Brynjar; Zwaginga, Jaap Jan; van Ham, S Marieke; ten Brinke, Anja. Storage-induced platelet apoptosis is a potential risk factor for alloimmunization upon platelet transfusion. Frontiers in Immunology 2018; Volum 9. ISSN 1664-3224.s doi: 10.3389/fimmu.2018.01251.

  • Tiller, Heidi; Husebekk, Anne; Ahlen, Maria Therese; Stuge, Tor Brynjar; Skogen, Bjørn Ragnar. Current perspectives on fetal and neonatal alloimmune thrombocytopenia - Increasing clinical concerns and new treatment opportunities. International Journal of Women's Health 2017; Volum 9. ISSN 1179-1411.s 223 - 234.s doi: 10.2147/IJWH.S90753.

  • Dahl, Jesper; Refsum, Erle; Ahlen, Maria Therese; Egeland, Torstein; Jensen, Tore; Viken, Marte K; Stuge, Tor Brynjar; Acharya, Ganesh; Husebekk, Anne; Skogen, Bjørn Ragnar; Tiller, Heidi. Unraveling the role of maternal anti-HLA class I antibodies in fetal and neonatal thrombocytopenia?Antibody specificity analysis using epitope data. Journal of Reproductive Immunology 2017; Volum 122. ISSN 0165-0378.s 1 - 9.s doi: 10.1016/j.jri.2017.06.003.

  • Eksteen, Mariana; Heide, Gøril; Tiller, Heidi; Zhou, Yan; Nedberg, Nora Hersoug; Martinez, Inigo Zubiavrre; Husebekk, Anne; Skogen, Bjørn Ragnar; Stuge, Tor Brynjar; Kjær, Mette. Anti-human platelet antigen (HPA)-1a antibodies may affect trophoblast functions crucial for placental development: A laboratory study using an in vitro model. Reproductive Biology and Endocrinology 2017; Volum 15:28. ISSN 1477-7827.s 1 - 8.s doi: 10.1186/s12958-017-0245-6.

  • Dahl, J; Husebekk, Anne; Acharya, Ganesh; Flo, Kari; Stuge, Tor Brynjar; Skogen, Bjørn Ragnar; Straume, Bjørn; Tiller, Heidi. Maternal anti-HLA class I antibodies are associated with reduced birthweight in thrombocytopenic neonates. Journal of Reproductive Immunology 2016; Volum 113. ISSN 0165-0378.s 27 - 34.s doi: 10.1016/j.jri.2015.10.003.

  • Ahlen, Maria Therese; Husebekk, Anne; Killie, Ida Løken; Skogen, Bjørn Ragnar; Stuge, Tor Brynjar. T cell responses to human platelet antigen-1a involve a unique form of indirect allorecognition. JCI Insight 2016; Volum Sep 8 (1). ISSN 2379-3708.s e86558 - .s doi: 10.1172/jci.insight.86558.

  • Taylor, Erin B; Moulana, Mohadetheh; Stuge, Tor Brynjar; Quiniou, Sylvie M A; Bengten, Eva; Wilson, Melanie. A Leukocyte Immune-Type Receptor Subset Is a Marker of Antiviral Cytotoxic Cells in Channel Catfish, Ictalurus punctatus. Journal of Immunology 2016; Volum 196. ISSN 0022-1767.s 2677 - 2689.s doi: 10.4049/jimmunol.1502166.

  • Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation. Frontiers in Oncology 2015; Volum 5:87. ISSN 2234-943X.s doi: 10.3389/fonc.2015.00087.

  • Eksteen, Mariana; Tiller, Heidi; Averina, Maria; Heide, Gøril; Killie, Mette Kjær; Ghevaert, Cedric; Michaelsen, Terje Einar; Ihle, Øistein; Husebekk, Anne; Skogen, Bjørn Ragnar; Stuge, Tor Brynjar. Characterization of a human platelet antigen-1a-specific monoclonal antibody derived from a B cell from a woman alloimmunized in pregnancy. Journal of Immunology 2015; Volum 194 (12). ISSN 0022-1767.s 5751 - 5760.s doi: 10.4049/jimmunol.1401599.

  • Chung, Brile; Stuge, Tor Brynjar; Murad, John P.; Beilhack, Georg; Andersen, Emily; Armstrong, Brian D.; Weber, Jeffrey S.; Lee, Peter P.. Antigen-specific inhibition of high-avidity T cell target lysis by low-avidity T cells via trogocytosis. Cell reports 2014; Volum 8 (3). ISSN 2211-1247.s 871 - 882.s doi: 10.1016/j.celrep.2014.06.052.

  • Chang, Gwendolen Y; Kohrt, Holbrook E; Stuge, Tor Brynjar; Schwartz, Erich J; Weber, Jeffrey S; Lee, Peter P. Cytotoxic T lymphocyte responses against melanocytes and melanoma. Journal of Translational Medicine 2011; Volum 9 (1). ISSN 1479-5876.s doi: 10.1186/1479-5876-9-122.

  • Stuge, Tor Brynjar; Skogen, Bjørn Ragnar; Ahlen, Maria Therese; Husebekk, Anne; Urbaniak, SJ; Bessos, H. The Cellular immunobiology associated with fetal and neonatal alloimmune thrombocytopenia. Transfusion and Apheresis Science 2011; Volum 45 (1). ISSN 1473-0502.s 53 - 59.s doi: 10.1016/j.transci.2011.06.003.

  • Husebekk, Anne; Ahlen, Maria Therese; Killie, Mette Kjær; Tiller, Heidi; Eksteen, Mariana; Killie, Ida Løken; Heide, Gøril; Kjeldsen-Kragh, Jens; Skogen, Bjørn Ragnar; Stuge, Tor Brynjar. Blood group antigens and immune responses-detailed knowledge is necessary to prevent immunization and to follow up immunized individuals. ISBT Science Series 2010; Volum 5 (1). ISSN 1751-2816.s 24 - 26.

  • Skogen, Bjørn Ragnar; Killie, Mette Kjær; Kjeldsen-Kragh, Jens; Ahlen, Maria Therese; Tiller, Heidi; Stuge, Tor Brynjar; Husebekk, Anne. Reconsidering fetal and neonatal alloimmune thrombocytopenia with a focus on screening and prevention. Expert Review of Hematology 2010; Volum 3 (5). ISSN 1747-4086.s 559 - 566.s doi: 10.1586/EHM.10.49.

  • Ahlen, Maria Therese; Husebekk, Anne; Killie, Mette Kjær; Skogen, Bjørn Ragnar; Stuge, Tor Brynjar. T-cell responses associated with neonatal alloimmune thrombocytopenia: isolation of HPA-1a-specific, HLA-DRB3*0101-restricted CD4+ T cells. Blood 2009; Volum 113 (16). ISSN 0006-4971.s 3838 - 3844.s doi: 10.1182/blood-2008-09-178475.

  • Moulana, Mohadetheh; Evenhuis, Jason; Albertino, Mark; Godwin, Ulla; Kountikov, Evgueni I.; Stuge, Tor Brynjar; Wilson, Melanie; Bengten, Eva; Miller, Norman W.; McConnell, Thomas J.. Characterization of anti-channel catfish MHC class IIβ monoclonal antibodies. Veterinary Immunology and Immunopathology 2008; Volum 126. ISSN 0165-2427.s 120 - 130.s doi: 10.1016/j.vetimm.2008.06.012.

  • Siegel, Matthew; Bethune, Micheal T; Gass, Jonathan; Ehren, Jennifer; Xia, Jiang; Johannsen, Alexandre; Stuge, Tor Brynjar; Gray, Gary M; Lee, Peter P.; Khosla, Chaitan. Rational design of combination enzyme therapy for celiac sprue.. Chemistry and Biology 2006; Volum 13 (6). ISSN 1074-5521.s 649 - 658.s doi: 10.1016/j.chembiol.2006.04.009.

  • Kohrt, Holbrook E; Shu, Chen-Tsen; Stuge, Tor Brynjar; Holmes, Susan P; Weber, Jeffrey S; Lee, Peter P.. Rapid assessment of recognition efficiency and functional capacity of antigen-specific T-cell responses.. Journal of immunotherapy 2005; Volum 28 (4). ISSN 1524-9557.s 297 - 305.s doi: 10.1097/01.cji.0000162780.96310.e4.

  • Chen, Daniel S; Soen, Yoav; Stuge, Tor Brynjar; Lee, Peter P.; Weber, Jeffrey S; Brown, Patrick O; Davis, Mark M. Marked differences in human melanoma antigen-specific T cell responsiveness after vaccination using a functional microarray.. PLoS Medicine 2005; Volum 2 (10). ISSN 1549-1277.s doi: 10.1371/journal.pmed.0020265.

  • Stuge, Tor Brynjar; Holmes, Susan P; Saharan, Sahdev; Tuettenberg, Andrea; Roederer, Mario; Weber, Jeffrey S; Lee, Peter P.. Diversity and recognition efficiency of T cell responses to cancer.. PLoS Medicine 2004; Volum 1 (2). ISSN 1549-1277.s doi: 10.1371/journal.pmed.0010028.

  • Shen, Linling; Stuge, Tor Brynjar; Bengten, Eva; Wilson, Melanie; Chinchar, V. Gregory; Naftel, John P; Bernanke, Jayne M.; Clem, L. William; Miller, Norman W.. Identification and characterization of clonal NK-like cells from channel catfish (Ictalurus punctatus).. Developmental and Comparative Immunology 2004; Volum 28 (2). ISSN 0145-305X.s 139 - 152.s doi: 10.1016/S0145-305X(03)00119-8.

  • Weber, Jeffrey S; Sondak, Vernon K; Scotland, Ronaldo; Phillip, Ramila; Wang, Flora; Rubio, Valerie; Stuge, Tor Brynjar; Groshen, Susan G; Gee, Conway; Jeffery, Georgia G; Sian, Shirley; Lee, Peter P.. Granulocyte-macrophage-colony-stimulating factor added to a multipeptide vaccine for resected Stage II melanoma.. Cancer 2003; Volum 97 (1). ISSN 0008-543X.s 186 - 200.s doi: 10.1002/cncr.11045.

  • Shen, Linling; Stuge, Tor Brynjar; Evenhuis, Jason P; Bengten, Eva; Wilson, Melanie; Chinchar, V. Gregory; Clem, L. William; Miller, Norman W.. Channel catfish NK-like cells are armed with IgM via a putative FcmicroR.. Developmental and Comparative Immunology 2003; Volum 27 (8). ISSN 0145-305X.s 699 - 714.s doi: 10.1016/S0145-305X(03)00042-9.

  • Rubio, Valerie; Stuge, Tor Brynjar; Singh, Naileshni; Betts, Michael R; Weber, Jeffrey S; Roederer, Mario; Lee, Peter P.. Ex vivo identification, isolation and analysis of tumor-cytolytic T cells.. Nature Medicine 2003; Volum 9. ISSN 1078-8956.s 1377 - 1382.s doi: 10.1038/nm942.

  • Shen, Linling; Stuge, Tor Brynjar; Zhou, He; Khayat, Morad; Barker, Katherine S; Quiniou, Sylvie M A; Wilson, Melanie; Bengten, Eva; Chinchar, V. Gregory; Clem, L. William; Miller, Norman W.. Channel catfish cytotoxic cells: a mini-review.. Developmental and Comparative Immunology 2002; Volum 26 (2). ISSN 0145-305X.s 141 - 149.s doi: 10.1016/S0145-305X(01)00056-8.

  • Bengten, Eva; Quiniou, Sylvie M A; Stuge, Tor Brynjar; Katagiri, Takayuki; Miller, Norman W.; Clem, L. William; Warr, Gregory W.; Wilson, Melanie. The IgH locus of the channel catfish, Ictalurus punctatus, contains multiple constant region gene sequences: different genes encode heavy chains of membrane and secreted IgD.. Journal of Immunology 2002; Volum 169 (5). ISSN 0022-1767.s 2488 - 2497.s doi: 10.4049/jimmunol.169.5.2488.

  • Zhou, He; Stuge, Tor Brynjar; Miller, Norman W.; Bengten, Eva; Naftel, John P; Bernanke, Jayne M.; Chinchar, V. Gregory; Clem, L. William; Wilson, Melanie. Heterogeneity of channel catfish CTL with respect to target recognition and cytotoxic mechanisms employed.. Journal of Immunology 2001; Volum 167 (3). ISSN 0022-1767.s 1325 - 1332.s doi: 10.4049/jimmunol.167.3.1325.

  • Lee, Peter P.; Wang, F; Kuniyoshi, J; Rubio, Valerie; Stuge, Tor Brynjar; Groshen, Susan G; Gee, Conway; Lau, R; Jeffery, Georgia G; Margolin, K; Marty, V; Weber, Jeffrey S. Effects of interleukin-12 on the immune response to a multipeptide vaccine for resected metastatic melanoma.. Journal of Clinical Oncology 2001; Volum 19 (18). ISSN 0732-183X.s 3836 - 3847.s doi: 10.1200/JCO.2001.19.18.3836.

  • Khayat, Morad; Stuge, Tor Brynjar; Wilson, Melanie; Bengten, Eva; Miller, Norman W.; Clem, L. William. Thioredoxin acts as a B cell growth factor in channel catfish.. Journal of Immunology 2001; Volum 166 (5). ISSN 0022-1767.s 2937 - 2943.s doi: 10.4049/jimmunol.166.5.2937.

  • Jonuleit, Helmut; Giesecke-Tuettenberg, Andrea; Tüting, Thomas; Thurner-Schuler, Beatrice; Stuge, Tor Brynjar; Paragnik, Lydia; Kandemir, Ayten; Lee, Peter P.; Schuler, Gerold; Knop, Jürgen; Enk, Alexander H. A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection.. International Journal of Cancer 2001; Volum 93 (2). ISSN 0020-7136.s 243 - 251.s doi: 10.1002/ijc.1323.

  • Hawke, Noel A; Yoder, Jeffrey A; Haire, Robert N.; Mueller, Gail; Litman, Ronda T; Miracle, Ann L; Stuge, Tor Brynjar; Shen, Linling; Miller, Norman W.; Litman, Gary W. Extraordinary variation in a diversified family of immune-type receptor genes.. Proceedings of the National Academy of Sciences of the United States of America 2001; Volum 98 (24). ISSN 0027-8424.s 13832 - 13837.s doi: 10.1073/pnas.231418598.

  • Stuge, Tor Brynjar; Wilson, Melanie; Zhou, He; Barker, Katherine S; Bengten, Eva; Chinchar, V. Gregory; Miller, Norman W.; Clem, L. William. Development and analysis of various clonal alloantigen-dependent cytotoxic cell lines from channel catfish.. Journal of Immunology 2000; Volum 164 (6). ISSN 0022-1767.s 2971 - 2977.s doi: 10.4049/jimmunol.164.6.2971.

  • Barker, Katherine S; Quiniou, Sylvie M A; Wilson, Melanie; Bengten, Eva; Stuge, Tor Brynjar; Warr, Gregory W; Clem, L. William; Miller, Norman W.. Telomerase expression and telomere length in immortal leukocyte lines from channel catfish.. Developmental and Comparative Immunology 2000; Volum 24. ISSN 0145-305X.s 583 - 595.s doi: 10.1016/S0145-305X(00)00021-5.

  • Wilson, Melanie; Zhou, He; Bengten, Eva; Clem, L. William; Stuge, Tor Brynjar; Warr, Gregory W.; Miller, Norman W.. T-cell receptors in channel catfish: structure and expression of TCR alpha and beta genes.. Molecular Immunology 1998; Volum 35 (9). ISSN 0161-5890.s 545 - 557.s doi: 10.1016/S0161-5890(98)00037-6.

  • Miller, Norman W.; Wilson, Melanie; Bengten, Eva; Stuge, Tor Brynjar; Warr, Gregory W.; Clem, L. William. Functional and molecular characterization of teleost leukocytes.. Immunological Reviews 1998; Volum 166. ISSN 0105-2896.s 187 - 197.s doi: 10.1111/j.1600-065X.1998.tb01263.x.

  • Stuge, Tor Brynjar; Yoshida, Steven H; Chinchar, V. Gregory; Miller, Norman W.; Clem, L. William. Cytotoxic activity generated from channel catfish peripheral blood leukocytes in mixed leukocyte cultures.. Cellular Immunology 1997; Volum 177 (2). ISSN 0008-8749.s 154 - 161.s doi: https://doi.org/10.1006/cimm.1997.1106.

  • Hogan, Robert J; Stuge, Tor Brynjar; Clem, L. William; Miller, Norman W.; Chinchar, V. Gregory. Anti-viral cytotoxic cells in the channel catfish (Ictalurus punctatus).. Developmental and Comparative Immunology 1996; Volum 20 (2). ISSN 0145-305X.s 115 - 127.s doi: 10.1016/0145-305X(95)00043-S.

  • Clem, L. William; Bly, Jan E; Wilson, Melanie; Chinchar, V. Gregory; Stuge, Tor Brynjar; Barker, Katherine S; Luft, J. Christopher; Rycyzyn, Michael A; Hogan, Robert J; van Lopik, T; Miller, Norman W.. Fish immunology: the utility of immortalized lymphoid cells--a mini review.. Veterinary Immunology and Immunopathology 1996; Volum 54 (1-4). ISSN 0165-2427.s 137 - 144.s doi: 10.1016/S0165-2427(96)05682-6.

  • Stuge, Tor Brynjar; Miller, Norman W.; Clem, L. William. Channel catfish cytotoxic effector cells from peripheral blood and pronephroi are different. Fish and Shellfish Immunology 1995; Volum 5 (6). ISSN 1050-4648.s 469 - 471.s doi: 10.1006/fsim.1995.0044.

  • Yoshida, Steven H; Stuge, Tor Brynjar; Miller, Norman W.; Clem, L. William. Phylogeny of lymphocyte heterogeneity: cytotoxic activity of channel catfish peripheral blood leukocytes directed against allogeneic targets.. Developmental and Comparative Immunology 1995; Volum 19 (1). ISSN 0145-305X.s 71 - 77.s doi: 10.1016/0145-305X(94)00053-I.

  • Bøgwald, Jarl; Stensvåg, Klara; Stuge, Tor Brynjar; Jørgensen, Trond Ø.. Tissue localisation and immune responses in Atlantic Salmon, Salmo salar L., after oral administration of Aeromonas salmonicida, Vibrio anguillarum and Vibrio salmonicidia antigens. Fish and Shellfish Immunology 1994; Volum 4 (5). ISSN 1050-4648.s 353 - 368.s doi: 10.1006/fsim.1994.1031.

  • Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Immunoregulatory functions of Cancer-associated Fibroblasts from lung cancers. Cell Symposia: Cancer, Inflammation and immunity 2015-06-14 - 2015-06-16 2015.

  • Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation. Cell Symposia: Cancer, Inflammation & Immunity 2015-06-14 - 2015-06-16 2015.

  • Hellevik, Turid; Gorch, Laia; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. High-dose irradiation does not modify the immunosuppressive effects elicited by cancer-associated fibroblasts. Anticancer Research 2014; Volum 34 (10). ISSN 0250-7005.s 5945 - 5945.

  • Killie, Ida Løken; Ahlen, Maria Therese; Husebekk, Anne; Skogen, Bjørn Ragnar; Stuge, Tor Brynjar. Induction and detection of in vivo immune responses to HPA-1a in a novel murine model of fetal/neonatal alloimmune thrombocytopenia (FNAIT). European symposium on platelet and granulocyte immunology 2014-07-03 - 2014-07-06 2014.

  • Dahl, Jesper; Husebekk, Anne; Acharya, Ganesh; Flo, Kari; Stuge, Tor Brynjar; Skogen, Bjørn Ragnar; Straume, Bjørn; Tiller, Heidi. Maternal anti-HLA class 1 antibodies are associated with reduced birth weight in thrombocytopenic neonates. 39th Nordic Congress of Obstetrics and Gynecology 2014-06-10 - 2014-06-12 2014.

  • Martinez, Inigo Zubiavrre; Gorch, Laia; Stuge, Tor Brynjar; Hellevik, Turid. Immuno-modulatory properties of cancer-associated Fibroblasts and its changes during radiotherapy. Immune and stromal responses in cancerology: new challenges for therapeutic targeting 2014-10-01 - 2014-10-04 2014.

  • Gorch, Laia; Hellevik, Turid; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre. Immunomodulatory properties of Cancer-Associated Fibroblasts. Anticancer Research 2014; Volum 34 (10). ISSN 0250-7005.s 6050 - 6050.

  • Heide, Gøril; Stuge, Tor Brynjar; Skogen, Bjørn Ragnar; Husebekk, Anne; Ahlen, Maria Therese. The DR7-DQ2 Haplotype in a Native Norwegian Population. Scandinavian Journal of Immunology 2013; Volum 77 (5). ISSN 0300-9475.s 429 - 430.s doi: 10.1111/sji.12031.

  • Killie, Ida Løken; Husebekk, Anne; Ahlen, Maria Therese; Roalso, M.; Skogen, Bjørn Ragnar; Stuge, Tor Brynjar. ARE CURRENT MURINE MODELS OF FETAL/NEONATAL ALLOIMMUNE THROMBOCYTOPENIA BRINGING US CLOSER TO A BETTER UNDERSTANDING OF PATHOPHYSIOLOGY AND TREATMENT OF THE DISEASE?. Vox Sanguinis 2013; Volum 105. ISSN 0042-9007.s 252 - 252.

  • Eksteen, Mariana; Killie, Mette Kjær; Husebekk, Anne; Skogen, Bjørn Ragnar; Stuge, Tor Brynjar. A NOVEL HUMAN MONOCLONAL HPA-1A-SPECIFIC ANTIBODY IS A USEFUL TOOL FOR DIAGNOSTICS IN FETAL AND NEONATAL ALLOIMMUNE THROMBOCYTOPENIA. Vox Sanguinis 2013; Volum 105. ISSN 0042-9007.s 240 - 240.

  • Husebekk, Anne; Tiller, Heidi; Killie, Mette Kjær; Eksteen, Mariana; Ahlen, Maria Therese; Stuge, Tor Brynjar; Ni, H; Kjeldsen-Kragh, Jens; Skogen, Bjørn Ragnar. TOWARDS A PROPHYLACTIC TREATMENT OF HPA-1A-RELATED FETAL AND NEONATAL ALLOIMMUNE THROMBOCYTOPENIA (FNAIT). Vox Sanguinis 2012; Volum 103. ISSN 0042-9007.s 48 - 48.

  • Husebekk, Anne; Ahlen, Maria Therese; Killie, Mette Kjær; Tiller, Heidi; Eksteen, Mariana; Killie, Ida Løken; Heide, Gøril; Skogen, Bjørn Ragnar; Kjeldsen-Kragh, Jens; Stuge, Tor Brynjar. MATERNAL ALLOIMMUNE RESPONSE DURING PREGNANCY: BRAKE OF MATERNAL TOLERANCE TO FETAL HUMAN PLATELET ANTIGEN 1A ANTIGEN MAY BE ASSOCIATED WITH REDUCED PLACENTAL FUNCTION. Placenta 2011; Volum 32 (9). ISSN 0143-4004.s A121 - A121.

  • Eksteen, Mariana; Tiller, Heidi; Husebekk, Anne; Skogen, Bjørn Ragnar; Stuge, Tor Brynjar. GENERATION OF MONOCLONAL ANTI-HPA-1A ANTIBODIES BY IMMORTALIZATION OF MEMORY B CELLS FROM A WOMAN ALLOIMMUNIZED IN CONNECTION WITH PREGNANCY. Vox Sanguinis 2010; Volum 99. ISSN 0042-9007.s 52 - 53.

  • Bauerlin, C A; Brede, C; Riedel, Simone S.; Garrote, Ana-Laura Jordan; Kiesel, C; Ritz, Miriam; Schulz, S.; Beilhack, G F; Stuge, Tor Brynjar; Negrin, R S; Einsele, Hermann; Beilhack, Andreas. CD107 surface mobilization of peripheral blood T-cells to predict acute graft-versus-host disease. Bone Marrow Transplantation 2010; Volum 45 (Supp. 2). ISSN 0268-3369.s S117 - S117.

  • Husebekk, Anne; Mk, K; Stuge, Tor Brynjar; Tiller, H; Mt, A; Kjeldsen-Kragh, J; Skogen, Bjørn Ragnar. The knowledge of the pathophysiology of fetal/neonatal alloimmune thrombocytopenia is of importance to prevent immunization and to handle the immunized pregnancies in order to prevent hemorrhage. Vox Sanguinis 2008; Volum 95. ISSN 0042-9007.

  • Ahlen, Maria Therese; Killie, Mette Kjær; Skogen, Bjørn Ragnar; Husebekk, Anne; Stuge, Tor Brynjar. Isolation and Characterization of CD4+ T Cells Specific for the HPA 1a Epitope Associated with Neonatal Alloimmune Thrombocytopenia. Blood 2007; Volum 110 (11). ISSN 0006-4971.s 623a - 624a.

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