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Tveita, Torkjel

Professor /overlege, intensivmedisin
Institutt for klinisk medisin

Stillingsbeskrivelse:

Forskningsgruppeleder akuttmedisinsk-anestesiologisk forskningsgruppe.




Forskningsinteresser

Klinisk patofysiologi, aksidentell hypotermi, sirkulasjonsfysiologi.

Arbeider i CRIStin


  • Gaustad, Svein Erik; Kondratyev, Timofey; Eftedal, Ingrid; Tveita, Torkjel. Continuous hemodynamic monitoring in an intact rat model of simulated diving. Frontiers in Physiology 2020. ISSN 1664-042X.

  • Schanche, Torstein Lindahl; Kondratiev, Timofei; Tveita, Torkjel. Extracorporeal rewarming from experimental hypothermia: Effects of hydroxyethyl starch versus saline priming on fluid balance and blood flow distribution. Experimental Physiology 2019. ISSN 0958-0670.s doi: 10.1113/EP087786.

  • Tveita, Torkjel; Arteaga, Grace; Han, Young Soo; Sieck, Gary C.. Cardiac troponin-I phosphorylation underlies myocardial contractile dysfunction induced by hypothermia rewarming. American Journal of Physiology. Heart and Circulatory Physiology 2019; Volum 317 (4). ISSN 0363-6135.s H726 - H731.s doi: 10.1152/ajpheart.00101.2019.

  • Dietrichs, Erik Sveberg; Håheim, Brage; Kondratyev, Timofey; Traasdahl, Erik R.; Tveita, Torkjel. Effects of hypothermia and rewarming on cardiovascular autonomic control in vivo. Journal of applied physiology 2018; Volum 124 (4). ISSN 8750-7587.s 850 - 859.s doi: 10.1152/japplphysiol.00317.2017.

  • Dietrichs, Erik Sveberg; Tveita, Torkjel; Smith, Godfrey L. Hypothermia and cardiac electrophysiology - a systematic review of clinical and experimental data.. Cardiovascular Research 2018; Volum 115 (3). ISSN 0008-6363.s 501 - 509.s doi: 10.1093/cvr/cvy305.

  • Schaible, Niccole; Han, Young Soo; Tveita, Torkjel; Sieck, Gary C.. Role of superoxide ion formation in hypothermia/rewarming induced contractile dysfunction in cardiomyocytes. Cryobiology 2018; Volum 81. ISSN 0011-2240.s 57 - 64.s doi: 10.1016/j.cryobiol.2018.02.010.

  • Valkov, Sergey; Mohyuddin, Rizwan; Nilsen, Jan Harald; Schanche, Torstein Lindahl; Kondratyev, Timofey; Sieck, Gary C.; Tveita, Torkjel. Organ blood flow and O2 transport during hypothermia (27°C) and rewarming in a pig model. (fulltekst) Experimental Physiology 2018; Volum 104 (1). ISSN 0958-0670.s 50 - 60.s doi: 10.1113/EP087205.

  • Han, Young Soo; Schaible, Niccole; Tveita, Torkjel; Sieck, Gary C.. Discontinued stimulation of cardiomyocytes provides protection against hypothermia?rewarming-induced disruption of excitation?contraction coupling. Experimental Physiology 2018; Volum 103 (6). ISSN 0958-0670.s 819 - 826.s doi: 10.1113/EP086774.

  • Håheim, Brage; Kondratyev, Timofey; Dietrichs, Erik Sveberg; Tveita, Torkjel. The beneficial hemodynamic effects of afterload reduction by sodium nitroprusside during rewarming from experimental hypothermia. Cryobiology 2017; Volum 77. ISSN 0011-2240.s 75 - 81.s doi: 10.1016/j.cryobiol.2017.05.002.

  • Halsøy, Kathrine; Kondratyev, Timofey; Tveita, Torkjel; Bjertnaes, Lars J.. Effects of Constant Flow vs. Constant Pressure Perfusion on Fluid Filtration in Severe Hypothermic Isolated Blood-Perfused Rat Lungs. Frontiers in medicine 2016. ISSN 2296-858X.s doi: 10.3389/fmed.2016.00070.

  • Schaible, Niccole; Han, Young Soo; Hoang, Thuy; Arteaga, Grace; Tveita, Torkjel; Sieck, Gary. Hypothermia/rewarming disrupts excitation-contraction coupling in cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology 2016; Volum 310 (11). ISSN 0363-6135.s H1533 - H1540.s doi: 10.1152/ajpheart.00840.2015.

  • Dietrichs, Erik Sveberg; Sager, Georg; Tveita, Torkjel. Altered pharmacological effects of adrenergic agonists during hypothermia. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2016; Volum 24:143. ISSN 1757-7241.s 1 - 9.s doi: 10.1186/s13049-016-0339-8.

  • Dietrichs, Erik Sveberg; Schanche, Torstein; Kondratyev, Timofey; Gaustad, Svein Erik; Sager, Georg; Tveita, Torkjel. Negative inotropic effects of epinephrine in the presence of increased β-adrenoceptor sensitivity during hypothermia in a rat model. Cryobiology 2015; Volum 70 (1). ISSN 0011-2240.s 9 - 16.s doi: 10.1016/j.cryobiol.2014.10.012.

  • Dietrichs, Erik Sveberg; Kondratyev, Timofey; Tveita, Torkjel. Milrinone ameliorates cardiac mechanical dysfunction after hypothermia in an intact rat model. Cryobiology 2014; Volum 69 (3). ISSN 0011-2240.s 361 - 366.s doi: 10.1016/j.cryobiol.2014.09.002.

  • Dietrichs, Erik Sveberg; Håheim, Brage; Kondratyev, Timofey; Sieck, Gary C.; Tveita, Torkjel. Cardiovascular effects of levosimendan during rewarming from hypothermia in rat. Cryobiology 2014; Volum 69 (3). ISSN 0011-2240.s 402 - 410.s doi: 10.1016/j.cryobiol.2014.09.007.

  • Wold, Ragnhild Margrete; Kondratyev, Timofey; Tveita, Torkjel. Myocardial calcium overload during graded hypothermia and after rewarming in an in vivo rat model. Acta Physiologica 2013; Volum 207 (3). ISSN 1748-1708.s 460 - 469.s doi: 10.1111/apha.12003.

  • Filseth, Ole Magnus; How, Ole-Jakob; Kondratyev, Timofey; Gamst, Tor Magne; Sager, Georg; Tveita, Torkjel. Changes in cardiovascular effects of dopamine in response to graded hypothermia in vivo. Critical Care Medicine 2012; Volum 40 (1). ISSN 0090-3493.s 178 - 186.s doi: 10.1097/CCM.0b013e31822d78de.

  • Tveita, Anders; Dietrichs, Erik Sveberg; Tveita, Torkjel. Myocardial gene expression profiling of rewarming shock in a rodent model of accidental hypothermia. Cryobiology 2012; Volum 64 (3). ISSN 0011-2240.s 201 - 210.s doi: 10.1016/j.cryobiol.2012.01.009.

  • Tveita, Torkjel; Sieck, Gary C.. Effects of milrinone on left ventricular cardiac function during cooling in an intact animal model. Cryobiology 2012; Volum 65 (1). ISSN 0011-2240.s 27 - 32.s doi: 10.1016/j.cryobiol.2012.03.007.

  • Sveberg Dietrichs, Erik; Lindal, Sigurd; Næsheim, Torvind; Ingebrigtsen, Tor; Tveita, Torkjel. Altered Brain Myelin Sheath Morphology after Rewarming in Situ. Ultrastructural Pathology 2010; Volum 34 (2). ISSN 0191-3123.s 82 - 89.s doi: 10.3109/01913120903398753.

  • Filseth, Ole Magnus; How, Ole-Jakob; Kondratiev, Timofei; Gamst, Tor Magne; Tveita, Torkjel. Post-hypothermic cardiac left ventricular systolic dysfunction after rewarming in an intact pig model. (fulltekst) Critical Care 2010; Volum 14 (6). ISSN 1364-8535.s doi: 10.1186/cc9334.

  • Han, YS; Tveita, Torkjel; Prakash, YS; Sieck, GC. Mechanisms underlying hypothermia-induced cardiac contractile dysfunction. American Journal of Physiology. Heart and Circulatory Physiology 2010; Volum 298 (3). ISSN 0363-6135.s H890 - H897.s doi: 10.1152/ajpheart.00805.2009.

  • Ytrehus, Kirsti; Tveita, Torkjel; Bugge, Einar. Loss of heart phospholipid arachidonic acid without phospholipid peroxidation in anaesthetized rats rewarmed after prolonged deep hypothermia. Cryobiology 2009; Volum 59 (3). ISSN 0011-2240.s 297 - 301.s doi: 10.1016/j.cryobiol.2009.08.006.

  • han, ys; Tveita, Torkjel; Kondratiev, Timofei; prakash, y s; Sieck, GC. changes in cardiovascular beta-adrenoceptor responses during hypothermia. Cryobiology 2008; Volum 57 (3). ISSN 0011-2240.s 246 - 250.

  • Kondratiev, Timofei; Wold, Ragnhild Margrete; Aasum, Ellen; Tveita, Torkjel. Myocardial mechanical dysfunction and calcium overload following rewarming from experimental hypothermia in vivo. Cryobiology 2008; Volum 56. ISSN 0011-2240.s 15 - 21.s doi: 10.1016/j.cryobiol.2007.09.005.

  • Tveita, Torkjel; Thoner, Just; Klepstad, P; Dale, Ola; Jystad, A; jystad, a; Borchgrevink, Petter Chr.. A controlled comparison between single doses of intravenous and intramuscular morphine with respect to analgesic effects and patient safety. Acta Anaesthesiologica Scandinavica 2008; Volum 52 (7). ISSN 0001-5172.s 920 - 925.s doi: 10.1111/j.1399-6576.2008.01608.x.

  • Dale, Ola; Thoner, J; Nilsen, T; Tveita, Torkjel; Borchgrevink, PC; Klepstad, P. Serum and cerebrospinal fluid morphine pharmacokinetics after single doses of intravenous and intramuscular morphine after hip replacement surgery. European Journal of Clinical Pharmacology 2007; Volum 63. ISSN 0031-6970.s doi: 10.1007/s00228-007-0329-x.

  • Kondratiev, Timofei; Myhre, Eivind S.P.; Simonsen, Øystein Thunheim; Nymark, Tor-Bjarne; Tveita, Torkjel. Cardiovascular effects of epinephrine during rewarming from hypothermia in an intact animal model. Journal of applied physiology 2006; Volum 100 (2). ISSN 8750-7587.s 457 - 464.s doi: 10.1152/japplphysiol.00356.200.

  • Kondratiev, Timofei; Tveita, Torkjel. Effects of sympathetic stimulation during cooling on hypothermic as well as posthypothermic hemodynamic function. (sammendrag) Canadian Journal of Physiology and Pharmacology 2006; Volum 84 (october). ISSN 0008-4212.s 985 - 991.s doi: 10.1139/Y06-051.

  • Kondratiev, Timofei; Flemming, Kristina; Myhre, Eivind S. P.; Sovershaev, Mikhail; Tveita, Torkjel. Is oxygen supply a limiting factor for survival during rewarming from profound hypothermia?. American Journal of Physiology. Heart and Circulatory Physiology 2006; Volum 291. ISSN 0363-6135.s H441 - H450.

  • Egorina, Elena; Sovershaev, Mikhail; Kondratiev, Timofei; Olsen, Jan Ole; Tveita, Torkjel; Østerud, Bjarne. Induction of monocytic TF expression after rewarming from hypothermia in vivo is counteracted by heat shock in c-Jun-dependent manner. Arteriosclerosis, Thrombosis and Vascular Biology 2006; Volum 26. ISSN 1079-5642.s 2401 - 2406.

  • Tveita, Torkjel; Johansen, K; Lien, AH; Myklebust, Reidar; Lindal, Sigurd. Morphologic changes in tubular cells from in situ kidneys following experimental hypothermia and rewarming. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS) 2005; Volum 113 (1). ISSN 0903-4641.s 13 - 20.

  • Bøkenes, Lise; Alexandersen, Toril E.; Tveita, Torkjel; Østerud, Bjarne; Mercer, James. Physiological and haematological responses to cold exposure in young subjects. International Journal of Circumpolar Health 2004; Volum 63 (2). ISSN 1239-9736.s 115 - 128.

  • Bolle, Stein Roald; Halvorsen, Kjersti Engeseth; Tveita, torkjel; Hotvedt, ragnar; Bjertnaes, Lars J.. Abstracts from the 26th congress of The Scandinavian Society of Anaesthesiology, and Intensive Care Medicine. Acta Anaesthesiologica Scandinavica 2001; Volum 45. ISSN 0001-5172.

  • Dale, Ola; Klepstad, Pål; Tveita, Torkjel; Thoner, Just; Borchgrevink, Petter Chr.. Re: fra ketobemidon til oksykodon. Tidsskrift for Den norske legeforening 2017; Volum 137 (6). ISSN 0029-2001.s 423 - 423.s doi: 10.4045/tidsskr.17.0182.

  • Kuklin, Vladimir; Kondratyev, Timofey; Konkaeva, Maya; Akhatov, Nurlan; Sovershaev, MA; Konkaev, Aidos; Tveita, Torkjel; Dahl, Vegard. EFFECTS OF MORPHINE OR KETAMINE IN RATS WITH ASPHYXIAL CARDIAC ARREST: THE RESULTS OF PILOT STUDY. NAFs 59. Høstmøte 2017 2017-10-24 - 2017-10-27 2017.

  • Dietrichs, Erik Sveberg; McGlynn, Karen; Kondratiev, Timofei; Smith, Godfrey L; Tveita, Torkjel. Hypothermia-induced differential effects on cardiac depolarisation and repolarisation in vivo. EHRA Europace Cardiostim 2017 and the 41st EWGCCE Meeting 2017-06-17 - 2017-06-21 2017.

  • Dietrichs, Erik Sveberg; Håheim, Brage; Kondratiev, Timofei; Tveita, Torkjel. Electrophysiological properties of calcium-sensitiser levosimendan during rewarming from severe hypothermia in vivo. The 13th congress of the European Assosciation for Clinical Pharmacology and Therapeutics (EACPT) 2017-06-24 - 2017-06-27 2017.

  • Kuklin, Vladimir; Kondratyev, Timofey; Konkayeva, Maya; Akhatov, Nurlan; Sovershaev, Mikhail; Konkayev, Aidos; Tveita, Torkjel; Dahl, Vegard. Effects of morphine or ketamine in rats with asphyxial cardiac arrest: a pilot study. The International Anesthesia Research Society 2017 Annual Meeting and International science symposium (data) (fulltekst) 2017-05-06 - 2017-05-09 2017.

  • Dietrichs, Erik Sveberg; McGlynn, Karen; Allen, Andrew; Connolly, Adam; Bishop, Martin; Burton, Francis; Tveita, Torkjel; Smith, Godfrey L. The differential effects of hypothermia on cardiac conduction and excitability. 40th EWGCCE Meeting 2016-09-02 - 2016-09-04 2016.

  • Dale, Ola; Klepstad, Pål; Tveita, Torkjel; Thoner, Just; Borchgrevink, Petter Chr.. Re: Fra ketobemidon til morfin eller oksykodon. Tidsskrift for Den norske legeforening 2016; Volum 136 (23-24). ISSN 0029-2001.s 1957 - 1957.s doi: 10.4045/tidsskr.16.1041.

  • Dietrichs, Erik Sveberg; Tveita, Torkjel. Pharmacological approaches to management of hypothermia-induced cardiac dysfunction. 2015 ISBN 978-82-7589-460-9.

  • Dietrichs, Erik Sveberg; Allan, Andrew; McGlynn, Karen; Burton, Francis; Tveita, Torkjel; Smith, Godfrey L. Moderate hypothermia induces pro-arrhythmic changes in cardiac electrophysiology. Arctic Frontiers 2014-01-19 - 2014-01-24 2014.

  • McGlynn, Karen; Dietrichs, Erik Sveberg; Tveita, Torkjel; Smith, Godfrey L. Hypothermic solutions cause reduced contractility in ventricular cardiomyocytes following rewarming. Arctic Frontiers 2014-01-19 - 2014-01-24 2014.

  • Dietrichs, Erik Sveberg; Allen, Andrew; McGlynn, Karen; Burton, Francis; Tveita, Torkjel; Smith, Godfrey L. Ventricular activation and repolarisation during deep hypothermia and rewarming using panoramic optical mapping of langendorff perfused rabbit hearts. EHRA Europace 2013-06-23 - 2013-06-26 2013.

  • Dietrichs, Erik Sveberg; Allen, Andrew; McGlynn, Karen; Burton, Francis; Tveita, Torkjel; Smith, Godfrey L. Measurements of ventricular activation and repolarisation during deep hypothermia and rewarming using panoramic optical mapping of isolated Langendorff perfused rabbit hearts. The 40th International Congress on Electrocardiology 2013-08-07 - 2013-08-10 2013.

  • Dietrichs, Erik Sveberg; Gaustad, Svein Erik; Kondratiev, T; Sager, Georg; Tveita, Torkjel. Hypothermia-induced dysfunction of the myocardial B1-adrenoceptor signal system. Accidental Hypothermia In The High North, The 3rd International Symposium On Accidental Hypothermia 2012-10-22 - 2012-10-23 2012.

  • Tveita, Torkjel; Sieck, Gary C.. The physiologic responses to epinephrine during cooling and after rewarming in vivo. Critical Care 2011; Volum 15 (5:R225). ISSN 1364-8535.s doi: 10.1186/cc10465.

  • Håheim, Brage; Dietrichs, Erik Sveberg; Tveita, Torkjel; Sieck, Gary C.. Cardiovascular effects of levosimendan during rewarming from severe hypothermia in vivo. The FASEB Journal 2011; Volum 25. ISSN 0892-6638.

  • Dietrichs, Erik Sveberg; Kondratiev, T; Tveita, Torkjel. Cardiovascular effects of the PDE3 inhibitor milrinone and calcium sensitizer levosimendan, during rewarming from severe hypothermia in vivo. Høstmøtet 2010-10-27 - 2010-10-29 2010.

  • Filseth, Ole magnus; How, Ole-Jakob; Kondratiev, Timofei; Gamst, Tor Magne; Tveita, Torkjel. CARDIAC FUNCTION DURING SEVERE IMMERSION HYPOTHERMIA AND REWARMING IN PIGS. Intensive Care Medicine 2010; Volum 36. ISSN 0342-4642.s S121 - S121.

  • Gaustad, Svein Erik; Kondratiev, Timofei; Møllerløkken, Andreas; Wisløff, Ulrik; Brubakk, Alf O; Tveita, Torkjel. Dynamic changes in cardiovascular function during diving and decompression at different core temperatures. EUBS 2010-09-10 - 2010.

  • Filseth, OM; How, Ole-Jakob; Kondratiev, Timofei; Gamst, Tor Magne; Sager, Georg; Tveita, Torkjel. DOPAMINE INFUSIONS IN NORMOTHERMIA, SEVERE HYPOTHERMIA AND DURING REWARMING: PHARMACOKINETICS AND CARDIOVASCULAR FUNCTION IN A PIG MODEL OF SURFACE COOLING AND REWARMING. Intensive Care Medicine 2010; Volum 36. ISSN 0342-4642.s S121 - S121.

  • Sveberg Dietrichs, Erik; Kondratiev, Timofei; Tveita, Torkjel. Cardiovascular effects of milrinone during rewarming from hypothermia in an intact animal model. 3rd International Hypothermia Symposium 2009-09-02 - 2009-09-05 2009.

  • Han, YS; Tveita, Torkjel; Kondratiev, Timofei; Sieck, GC. Change in physiologic response to isoproterenol induced by hypothermia is not reversed by rewarming. Acta Anaesthesiologica Scandinavica 2007; Volum 51. ISSN 0001-5172.s 27 - 27.

  • Wold, Ragnhild Margrete; Han, YS; Schaible, N; Pabelick, CM; Tveita, Torkjel; Prakash, YS; Sieck, GC. Altered cardiac mitochondrial Ca2+ regulation during rewarming following hypothermia. The FASEB Journal 2007; Volum 21. ISSN 0892-6638.

  • Wold, Ragnhild Margrete; Han, YS; Pabelick, CM; Tveita, Torkjel; Prakash, YS; Sieck, GC. Effects of epinephrine and superoxide disumutase on cardiac myocyte function during rewarming following hypothermia. The FASEB Journal 2007; Volum 21. ISSN 0892-6638.

  • Han, YS; Tveita, Torkjel; Kondratiev, Timofei; Prakash, YS; Sieck, GC. The physiologic response to isoproterenol during hypothermia and rewarming. The FASEB Journal 2007; Volum 21. ISSN 0892-6638.

  • Wold, Ragnhild Margrete; Han, YS; Schaible, N; Pabelick, CM; Tveita, Torkjel; Prakash, YS; Sieck, GC. Adverse effects of Epinephrine on cardiac mitochondrial Ca2+ buffering during rewarming from experimental hypothermia. Acta Anaesthesiologica Scandinavica 2007; Volum 51. ISSN 0001-5172.s 27 - 28.

  • Wold, Ragnhild Margrete; Han, Y; Schaible, N; Pabelick, M; Tveita, Torkjel; Prakash, Y; Sieck, G. Rewarming shock is related to hypothermia-induced calcium overload and altered mitochondrial Ca2+ regulation. Acta Anaesthesiologica Scandinavica 2007; Volum 51. ISSN 0001-5172.

  • Egorina, elena; Sovershaev, Mikhail; Kondratiev, Timofei; Olsen, Jan Ole; Tveita, torkjel; Østerud, Bjarne. Heat Shock Prevents Tissue Factor Induction after Rewarming from Lethal Hypothermia in a c-Jun-Dependent Manner. American Society of Hematology 48th Annual Meeting 2006-12-08 - 2006-12-12 2006.

  • Kondratiev, Timofei; Tveita, torkjel. Hypothermia-induced myocardial dysfunction. An in vivo experimental study with special reference to effects of epinephrine applied for posthypothermic cardiovascular resuscitation. 2006 ISBN 82-7589-169-8.

  • Egorina, elena; Sovershaev, Mikhail; Kondratiev, Timofei; Olsen, Jan Ole; Tveita, torkjel; Østerud, Bjarne. Heat shock prevents tissue factor expression after rewarming from lethal hypothermia in c-Jun-dependent manner. American Society of Hematology 2006-12-09 - 2006-12-12 2006.

  • Wold, Ragnhild Margrete; Kondratiev, Timofei; Tveita, Torkjel. Myocardial calcium control during short- and long-lasting hypothermia and rewarming in an in situ rat model. Journal of Molecular and Cellular Cardiology 2005; Volum 38. ISSN 0022-2828.s 1082 - 1082.

  • Filseth, OM; Kondratiev, TR; Wold, R; Tveita, Torkjel. Varighet av ekstrakorporeal revarming etter aksidentell hypoterm sirkulasjonsstans: Jo kortere, jo bedre?. Høstmøtet 2004-10-20 - 2004-10-23 2004.

  • Kondratiev, Timofei; Wold, Ragnhild Margrete; Tveita, torkjel. Effects of hypothermia and rewarming on myocardial calcium control in an intact animal model. Høstmøte, Norsk anestesiologisk forening 2003-10-21 - 2003-10-24 2003.

  • Kondratiev, Timofei; Tveita, torkjel. Presistent myocardial depression during hypothermia and rewarming following sympathetic stimulation during cooling. The 26th Congress of The Scandinavian Society of Anaesthesiology and Intensive Care Medicine 2001-06-13 - 2001-06-17 2001.

  • Kondratiev, Timofei; Simonsen, Øystein; Tor-Bjarne, Nymark; Tveita, torkjel. Altered dose dependent inotropic effects of epinephrine during hypothermia and rewarming. Publisert: Acta anaesthesiologica scandinavica, (supplement), 115 (45), 2001, p.73. The 26th Congress of The Scandinavian Society of Anaesthesiology and Intensive Care Medicine 2001-06-13 - 2001-06-17 2001.