Christian Widnes disputerer for ph.d.-graden i Helsevitenskapelige fag og vil offentlig forsvare avhandlingen:
«Sex differences in placental circulation»
Kort populærvitenskapelig sammendrag av avhandlingen:
The differences between males and females are evident already inside the mother´s womb. There seem to be sex-related differences in vulnerability and survival strategies throughout life.
During pregnancy, placenta sustains fetal life. Adequate blood supply to the placenta from both the mother and the fetus is important not only for normal growth and development of the fetus but also for long-term health of the baby after birth.
In the project presented in this thesis, we examined blood supply of the placenta from both maternal and fetal sides using two-dimensional B-mode and Doppler ultrasonography in order to investigate sex differences in the dynamics of blood flow (hemodynamics) and establish sex-specific normal reference values to refine diagnostics.
We found significant sex differences in some important parameters of feto-placental hemodynamics. We believe our newly established longitudinal sex-specific reference charts might help refining the surveillance of pregnancies at risk of placental/fetal circulatory compromise.
Veileder
Hovedveileder Professor Ganesh Achraya, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet
Biveileder Kari Flo, førsteamanuensis, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet under veiledningsperioden
Bedømmelseskomite
Professor Anne Cathrine Staff Head of Obstetrics and Gynecology, Institute of Clinical Medicine, University of Oslo Senior consultant, Oslo University Hospital, Oslo Norway - 1. opponent
Professor Sailesh Kumar Head of Academic Discipline of Obstetrics and Gynecology, Faculty of Medicine, Mater Research Instituter, The University of Queensland, Senior Staff Specialist Maternal Fetal Medicine/Obstetrics & Gynecology, Mater Mothers’ Hospital, Brisbane, Australia – 2. opponent
Marit Helene Hansen, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet – leder av komité
Disputasleder: Førsteamanuensis Kirsten Brun Kjelstrup, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet
Prøveforelesning over oppgitt emne holdes kl.1215 samme sted: 'Placentation and placental dysfunction in fetal growth restriction and preeclampsia: similarities and discrepancies'