Michael Sovershaev
Førsteamanuensis
Stillingsbeskrivelse
Associate professor, Hematological Research Group, Department of Clinical Medicine, University of Tromsø
Vladimir Kuklin (Bruggemann),
Michael Sovershaev,
Lars Johan Bjerner,
Philip Keith,
L. Keith Scott,
Owen Matthew Truscott Thomas
m.fl.:
Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction: a systematic review and meta-analysis
Critical Care 2024 DOI
Alexander Braadving Årving,
Thor Hilberg,
Michael Sovershaev,
Stig Tore Bogstrand,
Gudrun Høiseth
:
Falsely low phosphatidylethanol may be associated with biomarkers of haemolytic disease
Maria Averina,
Hilde Jensvoll,
Harald Strand,
Mikhail Sovershaev
:
A novel ANKRD26 gene variant causing inherited thrombocytopenia in a family of Finnish origin: Another brick in the wall?
Thrombosis Research 2017 DOI
Timofey Sovershaev,
Dusten Unruh,
Baldur Sveinbjørnsson,
John T. Fallon,
John-Bjarne Hansen,
Vladimir Y. Bogdanov
m.fl.:
A novel role of bone morphogenetic protein-7 in the regulation of adhesion and migration of human monocytic cells
Thrombosis Research 2016 DOI
Irina Starikova,
Simin Jamaly,
Antonio Sorrentino,
T Blondal,
Nadezhda Latysheva,
Mikhail Sovershaev
m.fl.:
Differential expression of plasma miRNAs in patients with unprovoked venous thromboembolism and healthy control individuals
Thrombosis Research 2015 DOI
Timofey Sovershaev,
Elena Egorina,
D. Unruh,
V.Y. Bogdanov,
John-Bjarne Hansen,
Mikhail Sovershaev
:
BMP-7 induces TF expression in human monocytes by increasing F3 transcriptional activity
Thrombosis Research 2015 DOI
Mikhail Sovershaev,
Elena Egorina,
Bjarne Østerud,
John-Bjarne Hansen
:
Evidence for direct transfer of tissue factor from monocytes to platelets in whole blood
Blood Coagulation and Fibrinolysis 2012 DOI
Basavaraj Goolyam,
Mikhail Sovershaev,
Elena Egorina,
Franz Gruber,
Vladimir Bogdanov,
John T. Fallon
m.fl.:
Circulating monocytes mirror the imbalance in TF and TFPI expression in carotid atherosclerotic plaques with lipid-rich and calcified morphology
Thrombosis Research 2012 DOI
Elena Egorina,
Timofey Sovershaev,
John-Bjarne Hansen,
Mikhail Sovershaev
:
BMP-2 inhibits TF expression in human monocytes by shutting down MAPK signaling and AP-1 transcriptional activity
Thrombosis Research 2012 DOI
Elena Egorina,
Mikhail Sovershaev,
John-Bjarne Hansen
:
The role of tissue factor in systemic inflammatory response syndrome
Blood Coagulation and Fibrinolysis 2011 DOI
Mikhail Sovershaev,
Elena Egorina,
TA Sovershaev,
birgit Svensson,
John-Bjarne Hansen
:
Increased expression of TF in BMP-7-treated human mononuclear cells depends on activation of select MAPK signaling pathways
Thrombosis Research 2011 SAMMENDRAG / DOI
Elena Egorina,
Mikhail Sovershaev,
Vladimir Bogdanov,
TA Sovershaev,
John T. Fallon,
Natalya Seredkina
m.fl.:
Low thrombogenicity of calcified atherosclerotic plaques is associated with bone morphogenetic protein-2-dependent inhibition of tissue factor expression
Blood Coagulation and Fibrinolysis 2011 DOI
Mikhail Sovershaev,
Elena Egorina,
Vladimir Bogdanov,
Natalya Seredkina,
JT Fallon,
Andrey Yurjevich Valkov
m.fl.:
Bone morphogenetic protein-7 increases thrombogenicity of lipid-rich atherosclerotic plaques via activation of tissue factor
Thrombosis Research 2010 DOI
GB Manjunath,
Franz Gruber,
Mikhail Sovershaev,
Hege Appelbom,
Bjarne Østerud,
Lars C Petersen
m.fl.:
The role of TFPI in regulation of TF-induced thrombogenicity on the surface of human monocytes
Thrombosis Research 2010 DOI
Mikhail Sovershaev,
elena Egorina,
John-Bjarne Hansen,
Bjarne Østerud,
Pal Pacher,
Johannes-Peter Stasch
m.fl.:
Soluble Guanylate Cyclase Agonists Inhibit Expression and Procoagulant Activity of Tissue Factor
Arteriosclerosis, Thrombosis and Vascular Biology 2009 DOI
Kristine Wærhaug,
Vladimir Kuklin,
Mikhail Kirov,
Mikhail Sovershaev,
Bodil Langbakk,
Ole C Ingebretsen
m.fl.:
Recombinant human activated protein C attenuates endotoxin-induced lung injury in awake sheep
Mikhail Sovershaev,
Karianne Fredenfeldt Lind,
hege Devold,
Trond Ø. Jørgensen,
John-Bjarne Hansen,
Bjarne Østerud
m.fl.:
No evidence for the presence of tissue factor in high-purity preparations of immunologically isolated eosinophils
Journal of Thrombosis and Haemostasis 2008 DOI
elena Egorina,
Mikhail Sovershaev,
Bjarne Østerud
:
Regulation of tissue factor procoagulant activity by post-translational modifications
Thrombosis Research 2008 DOI
elena Egorina,
Mikhail Sovershaev,
Jan Ole Olsen,
Bjarne Østerud
:
Granulocytes do not express but acquire monocyte-derived tissue factor in whole blood: evidence for a direct transfer
Blood 2008 DOI
elena Egorina,
Mikhail Sovershaev,
Jan Ole Olsen,
Bjarne Østerud
:
Granulocytes do not express but acquire monocyte-derived tissue factor in whole blood: evidence for a direct transfer
Blood 2007 DOI
Mikhail Sovershaev,
elena Egorina,
Franz Gruber,
Jan Ole Olsen,
Bjarne Østerud
:
High tissue factor-expressing human monocytes carry low surface CD36: application to intersubject variability
Journal of Thrombosis and Haemostasis 2007 DOI
elena Egorina,
Mikhail Sovershaev,
Bjarne Østerud
:
In-Cell Western assay: a new approach to visualize tissue factor in human monocytes
Journal of Thrombosis and Haemostasis 2006
Mikhail Sovershaev,
Elena Egorina,
Thomas Vennø Andreasen,
Anne Kristine Jonassen,
Kirsti Ytrehus
:
Preconditioning by 17 beta-estradiol in isolated rat heart depends on PI3-K/PKB pathway, PKC, and ROS
American Journal of Physiology. Heart and Circulatory Physiology 2006
Timofei Kondratiev,
Kristina Flemming,
Eivind S. P. Myhre,
Mikhail Sovershaev,
Torkjel Tveita
:
Is oxygen supply a limiting factor for survival during rewarming from profound hypothermia?
American Journal of Physiology. Heart and Circulatory Physiology 2006
Elena Egorina,
Mikhail Sovershaev,
Timofei Kondratiev,
Jan Ole Olsen,
Torkjel Tveita,
Bjarne Østerud
:
Induction of monocytic TF expression after rewarming from hypothermia in vivo is counteracted by heat shock in c-Jun-dependent manner
Arteriosclerosis, Thrombosis and Vascular Biology 2006
Vsevolod Kuzkov,
Mikhail Kirov,
Mikhail Sovershaev,
Vladimir Kuklin,
Evgeny Suborov,
Kristine Wærhaug
m.fl.:
Extravascular lung water determined with single transpulmonary thermodilution correlates with the severity of sepsis-induced acute lung injury
Critical Care Medicine 2006
Franz Gruber,
Trond Lamark,
Aileeen Cathrine Ånonli,
Mikhail Sovershaev,
M Olsen,
T Gedde-Dahl
m.fl.:
Selecting and deselecting imatinib-resistant clones: observations made by longitudinal, quantitative monitoring of mutated BCR-ABL
Leukemia 2005
Elena Egorina,
Mikhail Sovershaev,
Geir Bjørkøy,
Franz Gruber,
Jan Ole Olsen,
Behnaz Parhami-Seren
m.fl.:
Intracellular and surface distribution of monocyte tissue factor - Application to intersubject variability
Vladimir Kuklin,
Mikhail Kirov,
Mikhail Sovershaev,
thomas vennØ Andreasen,
Ole Christian Ingebretsen,
Kirsti Ytrehus
m.fl.:
Tezosentan-induced attenuation of lung injury in endotoxemic sheep is associated with reduced activation of protein kinase C
Critical Care 2005
Vladimir Kuklin,
Mikhail Sovershaev,
thomas vennØ Andreasen,
Vegard Skogen,
Kirsti Ytrehus,
Lars J. Bjertnaes
:
Tezosentan reduces the microvascular filtration coefficient in isolated lungs from rats subjected to cecum ligation and puncture
Critical Care 2005 DATA
Vladimir Kuklin,
Timofey Kondratyev,
Maya Konkayeva,
Nurlan Akhatov,
Mikhail Sovershaev,
Aidos Konkayev
m.fl.:
Effects of morphine or ketamine in rats with asphyxial cardiac arrest: a pilot study
Timofey Sovershaev,
Dusten Unruh,
Vladimir Bogdanov,
John-Bjarne Hansen,
Mikhail Sovershaev
:
BONE MORPHOGENETIC PROTEIN 7 UPREGULATES ADHESIVE AND MIGRATORY PROPERTIES OF HUMAN MONOCYTIC CELLS VIA β2 INTEGRIN-BMP RECEPTOR TYPE II CROSSTALK
2015
Timofey Sovershaev,
Elena Egorina,
Vladimir Bogdanov,
John-Bjarne Hansen,
Mikhail Sovershaev
:
Plasma levels of bone morphogenetic proteins and circulating monocyte tissue factor in individuals with echolucent and echogenic carotid atherosclerosis
2013
Timofey Sovershaev,
Elena Egorina,
Svetlana Sovershaeva,
Valentina Gubkina,
John-Bjarne Hansen,
Mikhail Sovershaev
:
Perioperative plasma TF levels in patients with advanced coronary heart disease and heart failure subjected to off-pump coronary bypass grafting
2013
Simin Jamaly,
Irina Starikova,
Michael Sovershaev,
John-Bjarne Hansen
:
High expression levels of P-selectin glycoprotein ligand-1 positive microparticles in people with unprovoked venous thromboembolism
2013
Simin Jamaly,
Irina Starikova,
Michael Sovershaev,
John-Bjarne Hansen
:
Increased levels of P-selectin glycoprotein ligand-1
positive microparticles in patients with unprovoked
venous thromboembolism
2013
Irina Starikova,
Simin Jamaly,
Michael Sovershaev,
T Blondal,
Antonio Sorrentino,
John-Bjarne Hansen
:
The role of microRNA in the pathogenesis of venous
thromboembolism
2013
Oleg Evgenov,
elena Egorina,
Johannes-Peter Stasch,
Mikhail Sovershaev
:
Inhibition of expression and procoagulant activity of tissue factor by soluble guanylate cyclase agonists in monocytes and endothelial cells
Nitric oxide 2008 DOI
Mikhail Sovershaev
:
Heat schock prevents tissue factor induction after rewarming from lethal hypthermia in a c-Jun-dependent matter
2007
Mikhail Sovershaev,
elena Egorina,
Yury Kiselev,
hege Devold,
Jan Ole Olsen,
Bjarne Østerud
:
The search for the origin of blood-borne tissue factor using siRNA-mediated gene silencing approach
2007
Mikhail Sovershaev,
elena Egorina,
hege Devold,
Jan Ole Olsen,
Bjarne Østerud
:
DETERMINATION OF TISSUE FACTOR ORIGIN USING SIRNA KNOCKDOWN APPROACH IN HUMAN PERIPHERAL BLOOD WHITE CELLS
2007
Mikhail Sovershaev,
Bjarne Østerud
:
Novel pathophysiological regulators of tissue factor expression in monocytes
UiT Norges arktiske universitet 2007
Mikhail Sovershaev,
elena Egorina,
Franz Gruber,
G. Bjorkoy,
Terje Johansen
:
Extracellular Signal-Regulated Protein Kinase 5 Mediates Resistance of Human Chronic Myeloid Leukemia K562 Cells to Imatinib
2006
elena Egorina,
Mikhail Sovershaev,
Timofei Kondratiev,
Jan Ole Olsen,
torkjel Tveita,
Bjarne Østerud
:
Heat Shock Prevents Tissue Factor Induction after Rewarming from Lethal Hypothermia in a c-Jun-Dependent Manner
2006
elena Egorina,
Mikhail Sovershaev,
Timofei Kondratiev,
Jan Ole Olsen,
torkjel Tveita,
Bjarne Østerud
:
Heat shock prevents tissue factor expression after rewarming from lethal hypothermia in c-Jun-dependent manner
2006
Mikhail Sovershaev
:
Signalling consequences of preconditioning with 17b-estradiol in isolated rat heart
2005
elena Egorina,
Mikhail Sovershaev,
Jan Ole Olsen,
Geir Bjørkøy,
Bjarne Østerud
:
Intersubject variability in intracellular and surface tissue factor distribution in LPS-stimulated monocytes
2005
Mikhail Sovershaev,
elena Egorina,
Thomas Vennø Andreasen,
anne kristine Jonassen,
Kirsti Ytrehus
:
Signalling consequences of preconditioning with 17beta-estradiol in isolated rat heart
01. januar 2005
Trine Lund,
Mikhail Sovershaev,
elena Egorina,
David Johansen,
Rudolph Riemersma,
Erik Wulfert
m.fl.:
Cardioprotection by 7beta-hydroxylated epiandrosterone (7-OH-EPIA)
01. januar 2005
Mikhail Sovershaev,
Elena Egorina,
Thomas Vennø Andreasen,
Anne Kristin Jonassen,
Kirsti Ytrehus
:
Signalling consequences of preconditioning with 17 beta-estradiol in isolated rat heart
Journal of Molecular and Cellular Cardiology 2005
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Publikasjoner utenom Cristin
Published 25 articles in international peer-reviewed scientific journals, 5 articles in Russian peer-reviewered journals, and over 80 abstracts on international and national scientific forums
Forskningsinteresser
Regulation of expression and function of tissue factor (TF) and tissue factor pathway inhibitor (TFPI) in monocytes and vascular wall
Pathogenesis of atherothrombosis