/ UiT Norges arktiske universitet
 

Ansatte IK - Arne Smalås.gif

Smalås, Arne O.


Instituttleder
Kjemi


Telefon: 776 44070
Mobil jobb / Mobil privat: /
Epost : arne.smalas@uit.no
Kontor/besøksadresse : REALF C 318/FPARK G 223 / Realfagsbygget /Forskningsparken 3
Funksjon : Instituttleder, Professor, Strukturkjemi, Nasjonalt senter for strukturbiologi (Norstruct)

Stillingsbeskrivelse:

Instituttleder, Institutt for kjemi

Professor i strukturkjemi

Leder Norstruct

Forskningsinteresser

  • Makromolekylers struktur og funksjon
  • Det molekylære opphav til enzymers kuldeadaptasjon
  • Utvikling av enzymer for anvendelse
  • Bioprospektering

Biografiske data

Født 1960, Namdalen

Can. Mag. (1985) Universitetet i Trondheim (nåværende NTNU), Can. Scient (1987) og Dr. scient. (1990) ved Universitetet i Tromsø.

Post doc 1990 - 1991 Universitetet i Tromsø

Post doc 1991 - 1992 Brookhaven National Laboratory, New York, USA

Post doc 1993 - 1994 Universitetet i Tromsø

Førsteamanuensis 1995 - 1997, Institutt for kjemi, Universitetet i Tromsø

Professor i strukturkjemi fra 1998, Institutt for kjemi, Universitetet i Tromsø

Professor II (20%) 2002-2007 i strukturbiologi og bioinformatikk, NTNU

Instituttleder fra 2007, Institutt for kjemi, Universitetet i Tromsø

Forskerprofil i Cristin

Klikk her

Arbeider i CRIStin

  • Bjerga, Gro Elin Kjæreng; Hjerde, Erik; De Santi, Concetta; Williamson, Adele Kim; Smalås, Arne O.; Willassen, Nils Peder; Altermark, Bjørn. High quality draft genome sequence of Streptomyces sp. strain AW19M42 isolated from a sea squirt in Northern Norway. Standards in Genomic Sciences 2014; Volum 9 (3). ISSN 1944-3277.
  • Hjerde, Erik; Pierechod, Marcin Miroslaw; Williamson, Adele Kim; Bjerga, Gro Elin Kjæreng; Willassen, Nils Peder; Smalås, Arne O.; Altermark, Bjørn. Draft Genome Sequence of the Actinomycete Rhodococcus sp. Strain AW25M09, Isolated from the Hadsel Fjord, Northern Norway. Genome Announcements 2013; Volum 1 (2). ISSN 2169-8287.s doi: 10.1128/genomeA.00055-13.
  • Purohit, Amit Anand; Johansen, Jostein a; Hansen, Hilde; Leiros, Hanna-Kirsti S.; Kashulin, Alexander; Karlsen, Christian; Smalås, Arne O.; Haugen, Peik; Willassen, Nils Peder. Presence of acyl-homoserine lactones in 57 members of the Vibrionaceae family. Journal of Applied Microbiology 2013; Volum 115 (3). ISSN 1364-5072.s 835 - 847.s doi: 10.1111/jam.12264.
  • Gurung, Man Kumari; Ræder, Inger Lin Uttakleiv; Altermark, Bjørn; Smalås, Arne O.. Characterization of the sialic acid synthase from Aliivibrio salmonicida suggests a novel pathway for bacterial synthesis of 7-O-acetylated sialic acids. Glycobiology 2013; Volum 23 (7). ISSN 0959-6658.s 806 - 819.s doi: 10.1093/glycob/cwt018.
  • Assefa, Netsanet Gizaw; Niiranen, Laila; Willassen, Nils P; Smalås, Arne O.; Moe, Elin. Thermal unfolding studies of cold adapted uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua). A comparative study with human UNG. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology 2012; Volum 161 (1). ISSN 1096-4959.s 60 - 68.s doi: 10.1016/j.cbpb.2011.09.007.
  • Ræder, Inger Lin Uttakleiv; Moe, Elin; Willassen, Nils Peder; Smalås, Arne Oskar; Leiros, Ingar. Structure of uracil-DNA N-glycosylase (UNG) from Vibrio cholerae: mapping temperature adaptation through structural and mutational analysis. Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 2010; Volum 66. ISSN 1744-3091.s 130 - 136.s doi: 10.1107/S1744309109052063.
  • Kyomuhendo, Peter; Myrnes, Bjørnar; Brandsdal, Bjørn Olav; Smalås, Arne; Nilsen, Inge Waller; Helland, Ronny. Thermodynamics and structure of a salmon cold active goose-type lysozyme. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology 2010; Volum 156 (4). ISSN 1096-4959.s 254 - 263.s doi: 10.1016/j.cbpb.2010.04.002.
  • Szlachcic, Anna; Zakrzewska, M; Krowarsch, D; Os, vibeke; Helland, Ronny; Smalås, Arne Oskar; Otlewski, J. Structure of a highly stable mutant of human fibroblast growth factor 1. Acta Crystallographica Section D: Biological Crystallography 2009; Volum 65. ISSN 0907-4449.s 67 - 73.s doi: 10.1107/S0907444908039486.
  • Kyomuhendo, Peter; Nilsen, Inge Waller; Brandsdal, Bjørn Olav; Smalås, Arne O.. Structural evidence for the lack of inhibition of fish goose-type lysozymes by a bacterial inhibitor of lysozyme. Journal of Molecular Modeling 2008; Volum 14. ISSN 0948-5023.s 777 - 788.s doi: 10.1007/s00894-008-0317-9.
  • Olufsen, Magne; Papaleo, Elena; Smalås, Arne Oskar; Brandsdal, Bjørn Olav. Ion pairs and their role in modulating stability of cold- and warm-active uracil DNA glycosylase. Proteins: Structure, Function, and Genetics 2008. ISSN 0887-3585.
  • Niiranen, Laila Mirja; Altermark, Bjørn; Brandsdal, Bjørn Olav; Leiros, Hanna-Kirsti S.; Helland, Ronny; Smalås, Arne Oskar; Willassen, Nils Peder. Effects of salt on the kinetics and thermodynamic stability of endonuclease I from Vibrio salmonicida and Vibrio cholerae. The FEBS Journal 2008; Volum 275. ISSN 1742-464X.s 1593 - 1605.s doi: 10.1111/j.1742-4658.2008.06317.x.
  • Olufsen, Magne; Smalås, Arne Oskar; Brandsdal, Bjørn Olav. Electrostatic interactions play an essential role in DNA repair and cold-adaptation of Uracil DNA glycosylase. Journal of Molecular Modeling 2008; Volum 14. ISSN 0948-5023.
  • Kyomohendo, Peter; Nilsen, Inge W; Brandsdal, Bjørn Olav; Smalås, Arne Oskar. Inhibition of marine g-type lysozymes by invertebrate inhibitor of lysozyme. Journal of Molecular Modeling 2008; Volum 14. ISSN 0948-5023.s 777 - 788.
  • Altermark, Bjørn; Helland, Ronny; Moe, Elin; Willassen, Nils Peder; Smalås, Arne Oskar. Environmental adaptation of endonuclease I from Vibrio salmonicida. Acta Crystallographica Section D: Biological Crystallography 2008; Volum 64. ISSN 0907-4449.s 368 - 376.
  • Ræder, Inger Lin Uttakleiv; Leiros, Ingar; Willassen, Nils Peder; Smalås, Arne Oskar; Moe, Elin. Uracil-DNA N-glycosylase (UNG) from the marine, psychrophilic bacterium Vibrio salmonicida shows cold adapted features A comparative analysis to Vibrio cholerae uracil-DNA N-glycosylase. Enzyme and microbial technology 2008; Volum 42 (7). ISSN 0141-0229.s 594 - 600.s doi: 10.1016/j.enzmictec.2008.02.005.
  • Altermark, Bjørn; Helland, Ronny; Moe, Elin; Willassen, Nils Peder; Smalås, Arne Oskar. Structural adaptation of endonuclease I from the cold-adapted and halophilic bacterium Vibrio salmonicida. Acta Crystallographica Section D: Biological Crystallography 2008; Volum 64. ISSN 0907-4449.s 368 - 376.s doi: 10.1107/S0907444908000097.
  • Olufsen, Magne; Brandsdal, Bjørn Olav; Smalås, Arne Oskar. Comparative unfolding studies of psychrophilic and mesophilic uracil DNA glycosylase: MD simulations show reduced thermal stability of the cold-adapted enzyme. Journal of Molecular Graphics and Modelling 2007; Volum 26. ISSN 1093-3263.s 124 - 134.s doi: 10.1016/j.jmgm.2006.10.003.
  • Altermark, Bjørn; Niiranen, Laila Mirja; Willassen, Nils Peder; Smalås, Arne Oskar; Moe, Elin. Comparative studies of endonuclease I from cold-adapted Vibrio salmonicida and mesophilic Vibrio cholerae. The FEBS Journal 2007; Volum 274. ISSN 1742-464X.s doi: 10.1111/j.1742-4658.2006.05580.x.
  • Ræder, Inger Liv Uttakleiv; Paulsen, Steinar; Smalås, Arne Oskar; Willassen, Nils Peder. Effect of fish skin mucus on the soluble proteome of Vibrio salmonicida analysed by 2-D gel electrophoresis and tandem mass spectrometry. Microbial Pathogenesis 2007; Volum 42. ISSN 0882-4010.s 36 - 45.s doi: 10.1016/j.micpath.2006.10.003.
  • Riise, Ellen Kristin; Lorentzen, marit sjo; Helland, Ronny; Smalås, Arne Oskar; Leiros, Hanna-Kirsti S.; Willassen, Nils Peder. The first structure of a cold-active catalase from Vibrio salmonicida at 1.96 angstrom reveals structural aspects of cold adaptation. Acta Crystallographica Section D: Biological Crystallography 2007; Volum 63. ISSN 0907-4449.s 135 - 148.s doi: 10.1107/S0907444906043812.
  • Altermark, Bjørn; Thorvaldsen, Steinar; Moe, Elin; Smalås, Arne Oskar; Willassen, Nils Peder. Sequence comparison and environmental adaptation of a bacterial endonuclease. Computational biology and chemistry (Print) 2007; Volum 31 (3). ISSN 1476-9271.s 163 - 172.s doi: 10.1016/j.compbiolchem.2007.03.003.
  • Moe, Elin; Leiros, Ingar; Smalås, Arne Oskar; McSweeney, Sean. The crystal structure of mismatch-specific uracil-DNA glycosylase (MUG) from Deinococcus radiodurans reveals a novel catalytic residue and broad substrate specificity. Journal of Biological Chemistry 2006; Volum 281. ISSN 0021-9258.
  • Helland, Ronny; Larsen, Atle Noralf; Smalås, Arne Oskar; Willassen, Nils Peder. The 1.8 angstrom crystal structure of a proteinase K-like enzyme from a psychrotroph Serratia species. The FEBS Journal 2006; Volum 273. ISSN 1742-464X.
  • Altermark, Bjørn; Smalås, Arne Oskar; Willassen, Nils Peder; Helland, Ronny. The structure of Vibrio cholerae extracellular endonuclease I reveals the presence of a buried chloride ion. Acta Crystallographica Section D: Biological Crystallography 2006; Volum 62. ISSN 0907-4449.s 1387 - 1391.
  • Almlöf, Martin; Åqvist, Johan; Smalås, Arne Oskar; Brandsdal, Bjørn Olav. Probing the effect of point mutations at protein-protein interfaces with free energy calculations. Biophysical Journal 2006; Volum 90. ISSN 0006-3495.
  • Mekonnen, Seble Merid; Olufsen, Magne; Smalås, Arne Oskar; Brandsdal, Bjørn Olav. Predicting proteinase specificities from free energy calculations. Journal of Molecular Graphics and Modelling 2006; Volum 25. ISSN 1093-3263.s 176 - 185.
  • Brandsdal, Bjørn Olav; Smalås, Arne Oskar; Åqvist, Johan. Free energy calculations show that acidic P1 variants undergo large pK(a) shifts upon binding to trypsin. Proteins: Structure, Function, and Genetics 2006; Volum 64. ISSN 0887-3585.s 740 - 748.
  • Olufsen, Magne; Smalås, Arne Oskar; Moe, Elin; Brandsdal, Bjørn Olav. Increased flexibility as a strategy for cold adaptation - A comparative molecular dynamics study of cold- and warm-active uracil DNA glycosylase. Journal of Biological Chemistry 2005; Volum 280. ISSN 0021-9258.
  • Leiros, Ingar; Moe, Elin; Smalås, Arne Oskar; McSweeney, Sean. Structure of the uracil-DNA N-glycosylase (UNG) from Deinococcus radiodurans. Acta Crystallographica Section D: Biological Crystallography 2005; Volum 61. ISSN 0907-4449.
  • Krowarsch, D; Zakrzewska, M; Smalås, Arne Oskar; Otlewski, J. Structure-function relationships in serine protease-bovine pancreatic trypsin inhibitor interaction. Protein peptide letters 2005; Volum 12. ISSN 0929-8665.
  • Moe, Elin; Leiros, Ingar; Riise, Ellen Kristin; Olufsen, Magne; Lanes, Olav; Smalås, Arne Oskar; Willassen, Nils Peder. Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua).. Journal of Molecular Biology 2004; Volum 343. ISSN 0022-2836.s 1221 - 1230.
  • Solem, Stein Tore; Brandsdal, Bjørn Olav; Smalås, Arne Oskar; Jørgensen, Trond Ø.. The primary structure and specificity determining residues displayed by recombinant salmon antibody domains. Molecular Immunology 2004; Volum 40. ISSN 0161-5890.s 1347 - 1360.
  • Czapinska, Honorata; Helland, Ronny; Smalås, Arne Oskar; Otlewski, Jacek. Crystal Structures of Five Bovine Chymotrypsin Complexes with P1 BPTI Variants. Journal of Molecular Biology 2004; Volum 344 (4). ISSN 0022-2836.s 1005 - 1020.
  • Leiros, Hanna-Kirsti S.; Leiros, Hanna Kirsti Schrøder; Brandsdal, Bjørn Olav; Andersen, Ole Andreas; Os, vibeke; Leiros, Ingar; Leiros, Ingar; Helland, Ronny; Otlewski, J.; Otlewski, Jacek; Willassen, Nils Peder; Smalås, Arne Oskar. Trypsin specificity as elucidated by LIE calculations, X-ray structures, and association constant measurements. Protein Science 2004; Volum 13. ISSN 0961-8368.s 1056 - 1070.
  • Moe, Elin; Leiros, Ingar; Riise, Ellen Kristin; Olufsen, Magne; Lanes, Olav; Smalås, Arne Oskar; Willassen, Nils Peder. Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua).. Journal of Molecular Biology 2004; Volum 343 (5). ISSN 0022-2836.s 1221 - 1230.
  • Leiros, Ingar; Moe, Elin; Lanes, Olav; Smalås, Arne Oskar; Willassen, Nils Peder. The crystal structure of uracil-DNA-glycosylase from Atlantic cod (Gadus morhua) reveals cold-adaptation fetures.. Acta Crystallographica Section D: Biological Crystallography 2003; Volum 59. ISSN 0907-4449.s 1357 - 1365.
  • Leiros, Ingar; Moe, Elin; Lanes, Olav; Smalås, Arne Oskar; Willassen, Nils Peder. The crystal structure of uracil-DNA-glycosylase from Atlantic cod (Gadus morhua) reveals cold-adaptation fetures.. Acta Crystallographica Section D: Biological Crystallography 2003; Volum 59. ISSN 0907-4449.s 1357 - 1365.
  • Helland, Ronny; Czapinska, Honorata; Leiros, Ingar; Olufsen, Magne; Otlewski, Jacek; Smalås, Arne Oskar. Structural Consequences of Accommodation of Four Non-cognate Amino Acid Residues in the S1 Pocket of Bovine Trypsin and Chymotrypsin. Journal of Molecular Biology 2003; Volum 333 (4). ISSN 0022-2836.s 845 - 861.
  • Jørgensen, T. O.; Solem, Stein Tore; Espelid, Sigrun; Warr, G. W.; Brandsdal, Bjørn Olav; Smalås, Arne Oskar. The antibody site in Atlantic salmon; phage display and modeling of scFv with anti-hapten binding ability. Developmental and Comparative Immunology 2002; Volum 26 (2). ISSN 0145-305X.s 201 - 206.s doi: 10.1016/S0145-305X(01)00065-9.
  • Lanes, Olav; Leiros, Ingar; Smalås, Arne Oskar; Willassen, Nils Peder. Identification, cloning, and expression of uracil-DNA glycosylase from Atlantic cod (gadus morhua): charcterization and homology modeling of the cold-active catalytic domain.. Extremophiles 2002; Volum 6. ISSN 1431-0651.s 73 - 86.
  • Leiros, H. -K. S.; McSweeney, S. M.; Smalås, Arne Oskar. Atomic resolution structures of trypsin provide insight into structural radiation damage.. Acta Crystallographica Section D: Biological Crystallography 2001; Volum 57. ISSN 0907-4449.s 488 - 497.
  • Brandsdal, Bjørn Olav; Smalås, Arne Oskar; Ågvist, A. O.. Electrostatic effects play a central role in cold adaptation of trypsin.. FEBS Letters 2001; Volum 499. ISSN 0014-5793.s 171 - 175.
  • Brandsdal, Bjørn Olav; Åqvist, J.; Smalås, Arne Oskar. Computational analysis of binding of P1-variants to trypsin.. Protein Science 2001; Volum 10. ISSN 0961-8368.s 1584 - 1596.
  • Heimstad, E. S.; Smalås, Arne Oskar; Kallenborn, R.. Environmental fate of chlorinated bornanes estimated by theoretical descriptors.. Chemosphere 2001; Volum 43. ISSN 0045-6535.s 665 - 674.
  • Otlewski, J.; Jaskolski, M.; Buczek, O.; Cierpicki, T.; Czapinska, H.; Krowarsch, D.; Smalås, Arne Oskar; Stachowiak, D.; Szpineta, A.; Dadlez, M.. Structure-function relationship of serine protease-protein inhibitor interaction.. Acta Biochimica Polonica 2001; Volum 48. ISSN 0001-527X.s 419 - 428.
  • Leiros, Ingar; Lanes, Olav; Sundheim, Ottar; Helland, Ronny; Smalås, Arne Oskar; Willassen, Nils Peder. Crystallization and preliminary X-ray diffraction analysis of a cold-adapted uracil-DNA glycosylase from Atlantic cod (Gadus morhua). Acta Crystallographica Section D: Biological Crystallography 2001; Volum 57. ISSN 0907-4449.s 1706 - 1708.
  • Leiros, Hanna-Kirsti S.; McSweeney, Seán M.; Smalås, Arne Oskar. Atomic resolution structures of trypsin provide insight into structural radiation damage. Acta Crystallographica Section D: Biological Crystallography 2001; Volum 57. ISSN 0907-4449.s 488 - 497.
  • Smalås, Arne Oskar; Leiros, Hanna-Kirsti S.; Os, V.; Willassen, Nils Peder. Cold adapted Enzymes. Biotechnology Annual Review 2000; Volum 6. ISSN 1387-2656.s 1 - 57.
  • Grzesiak, Agnieszka; Helland, Ronny; Smalås, Arne Oskar; Krowarsch, Daniel; Dadlez, Michal; Otlewski, Jacek. Substitutions at the P(1) position in BPTI strongly affect the association energy with serine proteinases. Journal of Molecular Biology 2000; Volum 301. ISSN 0022-2836.s 205 - 217.
  • Brandsdal, Bjørn Olav; Smalås, Arne Oskar. Evaluation of protein-protein association energies by free energy perturbation calculations.. Protein Engineering 2000; Volum 13. ISSN 0269-2139.s 239 - 245.
  • Smalås, Arne Oskar; Leiros, H. -K. S.; Os, V.; Willassen, Nils Peder. Cold adapted enzymes.. Biotechnology Annual Review 2000; Volum 6. ISSN 1387-2656.s 1 - 57.
  • Leiros, H. -K. S.; Willassen, Nils Peder; Smalås, Arne Oskar. Structural comparison of psychrophilic and mesophilic trypsins: elucidating the molecular basis of cold-adaptation.. European Journal of Biochemistry 2000; Volum 267 (4). ISSN 0014-2956.s 1039 - 1049.
  • Gorfe, A.A.; Brandsdal, Bjørn Olav; Leiros, Hanna-Kirsti S.; Helland, Ronny; Smalås, Arne Oskar. Electrostatics of mesophilic and psychrophilic trypsin isoenzymes: qualitative evaluation of electrostatic differences at the substrate binding site. Proteins: Structure, Function, and Genetics 2000; Volum 40. ISSN 0887-3585.s 207 - 217.
  • Helland, Ronny; Berglund, Gunnar Inge; Otlewski, Jacek; Apostoluk, Wlodek; Andersen, Ole Andreas; Willassen, Nils Peder; Smalås, Arne Oskar. High-resolution structures of three new trypsin-squash-inhibitor complexes: a detailed comparison with other trypsins and their complexes. Acta Crystallographica Section D: Biological Crystallography 1999; Volum 55. ISSN 0907-4449.s 139 - 148.
  • Helland, Ronny; Otlewski, Jacek; Sundheim, Ottar; Dadlez, Michal; Smalås, Arne Oskar. The crystal structures of the complexes between bovine b-trypsin and ten P1 variants of BPTI. Journal of Molecular Biology 1999; Volum 287. ISSN 0022-2836.s 923 - 942.
  • Krowarsch, D.; Dadlez, M.; Buczec, O.; Krokoszynsska, I.; Smalås, Arne Oskar. Inter-scaffolding additivity: Binding of P1 variants of bovine pancreatic trypsin inhi-bitor to four serine proteinases.. Journal of Molecular Biology 1999; Volum 289. ISSN 0022-2836.s 175 - 186.
  • Leiros, H. -K. S.; Willassen, Nils Peder; Smalås, Arne Oskar. Residue determinants and sequence analysis of cold-adapted trypsins.. Extremophiles 1999; Volum 3. ISSN 1431-0651.s 205 - 219.
  • Brandsdal, Bjørn Olav; Heimstad, E. S.; Sylte, Ingebrigt; Smalås, Arne Oskar. Comparative Molecular Dynamics of Mesophilic and Psychrophilic Homologues Studied by 1.2 ns Simulations.. Journal of Biomolecular Structure and Dynamics 1999; Volum 17. ISSN 0739-1102.s 493 - 506.
  • Leiros, Hanna-Kirsti S.; Willassen, Nils Peder; Smalås, Arne Oskar. Residue determinants and sequence analysis of cold-adapted trypsins. Extremophiles 1999; Volum 3. ISSN 1431-0651.s 205 - 219.
  • Leiros, Hanna-Kirsti S.; Willassen, Nils Peder; Smalås, Arne Oskar. Structural comparison of psychrophilic and mesophilic trypsins. Elucidating the molecular basis of cold-adaptation. European Journal of Biochemistry 1999; Volum 267. ISSN 0014-2956.s 1039 - 1049.
  • Berglund, G. I.; Outzen, H.; Smalås, Arne Oskar; Willassen, Nils Peder. Purification and Characterization of Pancreatic Elastase from the North Atlantic Salmon (Salmo salar).. Molecular Marine Biology and Biotechnology 1998; Volum 7. ISSN 1053-6426.s 105 - 114.
  • Schrøder, H. -K.; Willassen, Nils Peder; Smalås, Arne Oskar. Structure of a Non-Psychrophilic Trypsin from a Cold-Adapted Fish Species.. Acta Crystallographica Section D: Biological Crystallography 1998; Volum 54. ISSN 0907-4449.s 780 - 798.
  • Helland, Ronny; Leiros, Ingar; Berglund, Gunnar Inge; Willassen, Nils Peder; Smalås, Arne Oskar. The crystal structure of anionic salmon trypsin in complex with bovine pancreatic trypsin inhibitor.. European Journal of Biochemistry 1998; Volum 256 (2). ISSN 0014-2956.s 317 - 324.
  • Schrøder, Hanna-Kirsti; Willassen, Nils Peder; Smalås, Arne Oskar. Structure of a Non-Psychrophilic Trypsin From a Cold-Adapted Fish Species.. Acta Crystallographica Section D: Biological Crystallography 1998; Volum 54. ISSN 0907-4449.s 780 - 798.
  • Outzen, heidi; Berglund, Gunnar; Smalås, Arne Oskar; Willassen, Nils Peder. Temperature and pH Sensitivity of trypsins from Atlantic Salmon (Salmo salar) in Comparison with Bovine and Porcine Trypsin.. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology 1996; Volum 115. ISSN 1096-4959.s 33 - 45.
  • Berglund, Gunnar; Smalås, Arne Oskar; Hordvik, Asbjørn; Willassen, Nils Peder. The crystal structure of salmon pancreatic elastase at 1.6 Å resolution. Acta Crystallographica Section D: Biological Crystallography 1995; Volum 51. ISSN 0907-4449.s 925 - 937.
  • Male, Rune; Lorens, James B.; Smalås, Arne O.; Rungruangsak-Torrissen, Krisna. Molecular cloning and characterization of anionic and cationic variants of trypsin from Atlantic salmon. http://onlinelibrary.wiley.com/doi/10.1111/j.1432-1033.1995.677zz.x/pdf. European Journal of Biochemistry 1995; Volum 232. ISSN 0014-2956.s 677 - 685.
  • Williamson, Adele Kim; Altermark, Bjørn; Pierechod, Marcin Miroslaw; Bjerga, Gro Elin Kjæreng; Pedersen, hege lynum; De Santi, Concetta; Willassen, Nils Peder; Smalås, Arne O.. Hot Investigations into Cold-Sourced Enzymes. The 6th international BIOPROSP Conference 2013-02-20 - 2013-02-22 2013.
  • Altermark, Bjørn; Ræder, Inger Lin Uttakleiv; Gurung, Man Kumari; Smalås, Arne O.. Sialic acids in marine bacteria. Glycobiology 2013; Volum 23 (11). ISSN 0959-6658.s 1390 - 1390.
  • Altermark, Bjørn; Ræder, Inger Lin Uttakleiv; Gurung, Man Kumari; Smalås, Arne O.. Sialic acids in marine bacteria.. Annual meeting of the Society for Glycobiology 2013-11-17 - 2013-11-20 2013.
  • Ræder, Inger Lin Uttakleiv; Gurung, Man Kumari; Altermark, Bjørn; Berg, Tor Olav; Helland, Ronny; Smalås, Arne O.. Sialic acid biosynthesis in marine bacteria. BIOPROSP 2013 2013-02-20 - 2013-02-22 2013.
  • Berg, Tor Olav; Ræder, Inger Lin Uttakleiv; Altermark, Bjørn; Gurung, Man Kumari; Smalås, Arne O.. Characterization of a Neuraminic acid synthase from the psychrophilic organism Moritella viscosa. The Norwegian Biochemical Society 49th Contact meeting 2013-01-31 - 2013-02-03 2013.
  • Gurung, Man Kumari; Altermark, Bjørn; Ræder, Inger Lin Uttakleiv; Helland, Ronny; Smalås, Arne O.. Features and structure of a sialic acid aldolase from Aliivibrio salmonicida. BIOPROSP 2013 2013-02-20 - 2013-02-22 2013.
  • Pedersen, hege lynum; Altermark, Bjørn; Hjerde, Erik; Williamson, Adele Kim; Pierechod, Marcin Miroslaw; Bjerga, Gro Elin Kjæreng; De Santi, Concetta; Willassen, Nils Peder; Smalås, Arne O.. Genome Sequencing of Bacteria Isolated from the Arctic Marine Environment. The 6th international BIOPROSP Conference 2013-02-20 - 2013-02-22 2013.
  • Gurung, Man Kumari; Ræder, Inger Lin Uttakleiv; Altermark, Bjørn; Leiros, Ingar; Ökvist, Mats; Smalås, Arne O.. Exploring sialic acid synthesizing enzymes from Aliivibrio salmonicida. The Norwegian Biochemical Society 48th Contact meeting 2012-01-19 - 2012-01-22 2012.
  • Ræder, Inger Lin Uttakleiv; Gurung, Man Kumari; Altermark, Bjørn; Leiros, Ingar; Ökvist, Mats; Smalås, Arne O.. Sialic acid biosynthesis in Aliivibrio salmonicida. BIOPROSP 2011 2011-02-23 - 2011-02-25 2011.
  • Gurung, Man Kumari; Ræder, Inger Lin Uttakleiv; Altermark, Bjørn; Leiros, Ingar; Ökvist, Mats; Smalås, Arne O.. Sialic acid biosynthesis in Aliivibrio salmonicida. The Norwegian Biochemical Society 47th Contact meeting 2011-02-03 - 2011-02-06 2011.
  • Altermark, Bjørn; Pierechod, Marcin Miroslaw; Williamson, Adele Kim; Bjerga, Gro Elin Kjæreng; Høgås, Stian Bjørn; Jørgensen, Trond Ø.; Willassen, Nils Peder; Smalås, Arne O.. Molecules For The Future “Novel enzyme activities from environmental libraries - MARZymes”. The 5th international Conference on Marine Bioprospecting. BIOPROSP 2011 2011-02-23 - 2011-02-25 2011.
  • Ökvist, Mats; Ræder, Inger Lin Uttakleiv; Leiros, Ingar; Smalås, Arne O.. Structure of sialic acid biosynthesis enzyme PtmG from Aliivibrio salmonicida. BIOPROSP 2011 2011-02-23 - 2011-02-25 2011.
  • Olsen, Odd-Arne; Johansen, Wenche; Emilsen, Sidsel; Belova, Tatiana; Liang, Zhe; Smalås, Arne; Johnson, Ken; Helland, Ronny; Schrøder Leiros, Hanna-Kirsti; Jakobsen, Kjetill S.; Shalchian-Tabrizi, Kamran; Quatrano, Ralph; Cove, David; Perroud, Pierre-Francois; Dutcher, Susan; Wilson, Robert; Wilson, Robert. Structural & functional significance of the DEK1 phytocalpain during land plant evolution from green algae. NBS kontaktmøte 2010-01-14 - 2010-01-17 2010.
  • Skogestad, Sigurd; Einarsrud, Mari-Ann; Fjellvåg, Helmer; Gundersen, Lise-Lotte; Hansen, Trond Vidar; Hemmingsen, Tor; Hemmingsen, Tor; Jensen, Vidar; Kallenborn, Roland; Salbu, Brit; Smalås, Arne; Walsø, Geir. Oppfølging av Kjemievalueringen 2009. 2010 ISBN 9788212027848.
  • Drabløs, Finn; Petersen, Kjell; Johansen, Jostein; Nygård, Ståle; Ahmad, Rafi; Smalås, Arne; Hovig, Eivind; Jonassen, Inge. The FUGE Bioinformatics platform: a central platform in the FUGE2 period. 22nd conference of The Society for Medical Innovation and Technology 2010-09-02 - 2010-09-04 2010.
  • Drabløs, Finn; Petersen, Kjell; Johansen, Jostein; Nygård, Ståle; Ahmad, Rafi; Smalås, Arne; Hovig, Eivind; Jonassen, Inge. The FUGE Bioinformatics platform: a central platform in the FUGE2 period. MITAT. Minimally invasive therapy & allied technologies 2010; Volum 19. ISSN 1364-5706.s 70 - 71.s doi: 10.3109/13645706.2010.500867.
  • Altermark, Bjørn; Ræder, Inger Lin Uttakleiv; Hadrovic, Martina; Leiros, Ingar; Smalås, Arne O.. Sialic Acid Synthesis in Aliivibrio salmonicida. 4th International BIOPROSP Conference on Marine Biotechnology 2009-02-24 - 2009-02-25 2009.
  • Ræder, Inger Lin Uttakleiv; Altermark, Bjørn; Hadrovic, Martina; Leiros, Ingar; Smalås, Arne O.. Sialic acid synthesis in Aliivibrio salmonicida. EUROCARB 2009 2009-07-19 - 2009-07-24 2009.
  • Moe, Elin; Leiros, Ingar; Hall, David Richard; Smalås, Arne Oskar; McSweeney, Sean. Structure/function studies of Base Excision Repair (BER) enzymes from the extreme radiation resistant bacterium Deinococcus radiodurans. The Norwegian Biochemical Society 44th Contact meeting 2008-01-17 - 2008-01-20 2008.
  • Assefa, Netsanet Gizaw; Moe, Elin; Smalås, Arne Oskar; Willassen, Nils Peder. Thermodynamic characterization of uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua). The FEBS Journal 2008; Volum 275. ISSN 1742-464X.s 188 - 188.
  • Altermark, Bjørn; Helland, Ronny; Niiranen, Laila Mirja; Moe, Elin; Brandsdal, Bjørn Olav; Smalås, Arne Oskar; Willassen, Nils Peder. Optimum enzymatic activity of endonuclease I from Vibrio salmonicida and Vibrio cholerae correlateswith the bacterial growth habitat. BIOPROSP 2006 2006-10-11 - 2006-10-12 2006.
  • Ræder, Inger Lin Uttakleiv; Leiros, Ingar; Willassen, Nils Peder; Smalås, Arne Oskar; Moe, Elin. Uracil-DNA N-glycosylase (UNG) from the marine psychrophilic bacterium Vibrio salmonicida shows cold adapted features. BIOPROSP 2006 2006-10-11 - 2006-10-12 2006.
  • Khan, Mahmud Tareq Hassan; Adekoya, Olayiwola Adedotun; Lorentzen, marit sjo; Willassen, Nils Peder; Smalås, Arne Oskar; Sylte, Ingebrigt. Molecular features and inhibition of the thermolysin family of enzymes. Open day 2006. PhD-school in Molecular and Structural Biology 2006-11-15 - 2006.
  • Mekonnen, Seble Merid; Olufsen, Magne; Smalås, Arne Oskar; Brandsdal, Bjørn Olav. Predicting Proteinase Specificities from Free Energy Calculations. International Workshop "New Approaches in Drug Design & Discovery" (data) 2005-03-21 - 2005-03-24 2005.
  • Moe, Elin; Leiros, Ingar; Smalås, Arne Oskar; McSweeney, Sean. Crystallisation and structure determination of a mismatch specific DNA glycosylase (MUG) from Deinococcus radiodurans. Functional genomics in the Nordic Countries 2005-09-05 - 2005.
  • Moe, Elin; Leiros, Ingar; Smalås, Arne Oskar; McSweeney, Sean. Crystallisation and structure determination of uracil-DNA glycosylases from Deinococcus radiodurans and Vibrio salmonicida. A Collaboration between ESRF and NorStruct.. The 3rd Norwegian User Meeting - Application of Synchrotron radiation 2005-03-10 - 2005-03-11 2005.
  • Yang, Nannan; Karlsen, Solveig; Steen, Ida Helene; Fedoy, AE; Raae, A.J.; Birkeland, NK; Smalås, Arne Oskar. 1.75 Å crystal structure of isocitrate dehydrogenase from Desulfotalea psychrophila.. The 3rd Norwegian synchrotron user meeting 2005-05-10 - 2005-05-11 2005.
  • Yang, Nannan; Espelid, sigrun; Willassen, Nils Peder; Smalås, Arne Oskar. Hypothetical proteins from Vibrio salmonicida genome: strategies for target selection, cloning and expression. . The Norwegian Biochemical Society 41st Contact meeting 2005-01-13 - 2005-01-16 2005.
  • Ræder, Inger Liv Uttakleiv; Pedersen, hege lynum; Paulsen, steinar; Jørgensen, Trond; Willassen, Nils Peder; Smalås, Arne Oskar. Proteomic studies of Vibrio Salmonicida. The Norwegian Biochemical Society 41st Contact meeting 2005-01-13 - 2005-01-16 2005.
  • Olufsen, Magne; Brandsdal, Bjørn Olav; Moe, Elin; Smalås, Arne Oskar. Increased Molecular Flexibility Plays a Central Role in Cold-Adaptation of Uracil DNA Glycosylase. BIOPROSP: symposium marine bioprospecting 2004-10-13 - 2004-10-14 2004.
  • Moe, Elin; Leiros, Ingar; Smalås, Arne Oskar; Willassen, Nils Peder. Screening for cold adapted enzymes. BIOPROSP 2004 2004-10-13 - 2004-10-14 2004.
  • Solem, Stein Tore; Muller, Anita; Willassen, Nils Peder; Smalås, Arne Oskar; Mjaaland, Siri; Jørgensen, Trond Ø.. Molecular aspects of antigenic determinants in the ISAV hemagglutinin. NORSTRUCT-hurtigruteseminar 2004-12-01 - 2004-12-03 2004.
  • Yang, Nannan; Steen, IH; Karlsen, Solveig; Fedoy, AE; Glærum, L; Stokke, R; Madsen, MS; Andersen, OA; Raae, A.J.; Martinez, A; Birkeland, NK; Smalås, Arne Oskar. Isocitrate dehydrogenases from various organisms: a model system to study structural basis of biological adaptations to extreme temperatures. 10th International Conference on the Crystallization of Biological Macromolecules 2004-06-05 - 2004-06-08 2004.
  • Altermark, Bjørn; Moe, Elin; Smalås, Arne Oskar; Willassen, Nils Peder. Are Lysines important for cold adaptation of Vibrio salmonicida nuclease?. BIOPROSP 2004 2004-10-13 - 2004-10-14 2004.
  • Moe, Elin; Leiros, Ingar; Smalås, Arne Oskar; McSweeney, Sean. Structure determination of mismatch specific uracil-DNA glycosylase (MUG) from the radiation resistant bacteria Deinococcus radiodurans. VI European Protein science meeting 2004-04-30 - 2005-05-04 2004.
  • Olufsen, Magne; Moe, Elin; Brandsdal, Bjørn Olav; Willassen, Nils Peder; Smalås, Arne Oskar. STRUCTURAL AND ENERGETIC ASPECTS OF PROTEIN DNA-RECOGNITION. hurtigrute seminar 2003-12-01 - 2003-12-02 2003.
  • Smalås, Arne Oskar. Psychrophilic enzymes: Structure-function relationship and molecular design. Invited lecture 2003-02-20 - 2003-02-20 2003.
  • Helland, Ronny; Czapinska, Honorata; Otlewski, Jacek; Willassen, Nils Peder; Smalås, Arne Oskar. Primary and secondary specificity of serine proteinases of the chymotrypsin family.. Strategies in Macromolecular Structure Determination at 3rd Generation Synchrotron Sources (EMBO practical course) 2003-06-17 - 2003.
  • Mekonnen, Seble Merid; Olufsen, Magne; Helland, Ronny; Brandsdal, Bjørn Olav; Willassen, Nils Peder; Smalås, Arne Oskar. Residue determinants for substrate specificity from computational analysis and modeling of protein-inhibitor complexes of the subfamily S8A subtilisin-like family of serine proteinases. The 4th European Work Shop in Drug Design (4EWDD) 2003-05-25 - 2003-06-01 2003.
  • Helland, Ronny; Adekoya, Olayiwola; Mekonnen, Seble Merid; Gjellesvik, Dag Rune; Edvardsen, Øyvind; Høgda, Kjell Arild; Grøttum, Karl Johan; Sylte, Ingebrigt; Smalås, Arne Oskar; Willassen, Nils Peder. Determination of Molecular Descriptors from Analysis of Sequence and Genome Data.. Bioinformatics 2002 2002-04-04 - 2002-04-07 2002.
  • Leiros, H. -K. S.; Smalås, Arne Oskar. Determination of three dimensional protein structures by use of the synchrotron radiation source at ESRF (European Synchrotron Radiation Facility) in Grenoble, France. Functional genomics in Tromsø 2001-10-17 - 2001-10-18 2001.
  • Helland, Ronny; Adekoya, Olayiwola; Mekonnen, Seble Merid; Gjellesvik, Dag Rune; Edvardsen, Øyvind; Høgda, Kjell Arild; Grøttum, Karl Johan; Sylte, Ingebrigt; Smalås, Arne Oskar; Willassen, Nils Peder. Determination of Molecular Descriptors from Analysis of Sequence and Genome Data.. Functional Genomics in Tromsø 2001-10-17 - 2001-10-18 2001.
  • Smalås, Arne Oskar; Helland, Ronny; Otlewski, J.; Sundheim, O.; Dadlez, M.. The crystal structures of the complexes between bovine -trypsin and ten P1 variants of BPTI.. XVIII Congress and general Assembly 1999-08-04 - 1999-08-13 1999.
  • Brandsdal, Bjørn Olav; Helland, Ronny; Sylte, Ingebrigt; Otlewski, J.; Smalås, Arne Oskar. Protein-protein recognition.. Talking Proteins: An EMBO workhsop on sequence analysis, modelling and simulation 1998-09-01 - 1998.
  • Leiros, H. -K. S.; Willassen, Nils Peder; Smalås, Arne Oskar. Trypsins from Fish: What is so special?. 9th Annual Biotechnology Center Sympositum 1998-11-12 - 1998.
  • Brandsdal, Bjørn Olav; Smalås, Arne Oskar. Reproduction of protein-protein association energies by free energy perturbation calculations.. Protein Eng. 1999-01-01 - 1998.
  • Schrøder, H. -K.; Smalås, Arne Oskar; Willassen, Nils Peder. Structure-Function Relation Studies of Trypsin from Cold-Adapted Species.. Proteins, Gordon Research Conference 1997-06-15 - 1997-06-20 1997.
  • Schrøder, H. -K.; Willassen, Nils Peder; Smalås, Arne Oskar. Crystal Structure of a New, Non-Psychrophilic Trypsin from a Cold-Adapted Fish Species.. 3rd Coastal Biotechnology Symposium and 8th Annual Biotechnology Center Symposium 1997-09-09 - 1997-09-10 1997.
  • Schrøder, H. -K.; Willassen, Nils Peder; Smalås, Arne Oskar. Crystal Structure of a Non-Psychrophilic Trypsin from a Cold-Adapted Fish Species.. Norsk Kjemisk Selskaps Landsmøte 1997-10-09 - 1997-10-10 1997.
  • Helland, Ronny; Berglund, Gunnar; Hansen, Lars Kr; Heimstad, Eldbjørg S.; Hordvik, Asbjørn; Leiros, Ingar; Leiros, Hanna-Kirsti S.; Os, vibeke; Outzen, Heidi; Willassen, Nils Peder; Smalås, Arne Oskar. Structure-Function Relation Studies of Enzymes from Cold Adapted Species.. Higher European Research Course for Users of Large Experimental Systems (HERCULES) 1995-02-26 - 1995-04-07 1995.



  •