Gunhild Mari Mælandsmo
Professor II
Remya Valsalakumari,
Abilash D Pandya,
Lina Prasmickaite,
Audun Sverre Myrset Kvalvaag,
Anne Grethe Myrann,
Andreas K. O. Åslund
m.fl.:
Preclinical Efficacy of Cabazitaxel Loaded Poly
(2-alkyl cyanoacrylate) Nanoparticle Variants
Mads Haugen,
Hedda von der Lippe Gythfeldt,
Eivind Valen Egeland,
Lisa Svartdal Normann,
Abhilash D. Pandya,
Lise-Lotte Vedin
m.fl.:
Liver X receptors induce antiproliferative effects in basal-like breast cancer
Salim Ghannoum,
Damiano Fantini,
Muhammad Zahoor,
Veronika Reiterer,
Santosh Phuyal,
Waldir Leoncio Netto
m.fl.:
A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression
Lisa Gregusson Svartdal,
Mads Haugen,
Vesa Hongisto,
Miriam Ragle Aure,
Suvi-Katri Leivonen,
Vessela N. Kristensen
m.fl.:
High-throughput screen in vitro identifies dasatinib as a candidate for combinatorial treatment with HER2-targeting drugs in breast cancer
Caroline Elisabeth Nunes-Xavier,
Maite Emaldi,
Janire Mingo,
Tove Ragnhild Øyjord,
Gunhild Mari Mælandsmo,
Øystein Fodstad
m.fl.:
The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma
Vigdis Nygaard,
Anne Hansen Ree,
Vegar Johansen Dagenborg,
Anne-Lise Børresen-Dale,
Bjørn von Gohren Edwin,
Åsmund Avdem Fretland
m.fl.:
A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases
Erik Knutsen,
Saikat Das Sajib,
Tonje Fiskaa,
James Bradley Lorens,
Thorarinn Gudjonsson,
Gunhild Mari Mælandsmo
m.fl.:
Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes
Solveig Pettersen,
Geir Frode Øy,
Eivind Valen Egeland,
Siri Juell,
Olav Engebråten,
Gunhild Mari Mælandsmo
m.fl.:
Breast cancer patient-derived explant cultures recapitulate in vivo drug responses
Gisella Figlioli,
Amandine Billaud,
Thomas U. Ahearn,
Natalia N. Antonenkova,
Heiko Becher,
Matthias W. Beckmann
m.fl.:
FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women
Caroline Elisabeth Nunes-Xavier,
Janire Mingo,
Maite Emaldi,
Karine Flem-Karlsen,
Gunhild Mari Mælandsmo,
Øystein Fodstad
m.fl.:
Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer
Frontiers in Oncology 2022 DOI
Marta Sølvi Nyakas,
Karianne Giller Fleten,
Mads Haugland Haugen,
Nikolai Engedal,
Christina Sveen,
Inger Nina Farstad
m.fl.:
AXL inhibition improves BRAF-targeted treatment in melanoma
Marta Tellez Gabriel,
Xavier Tekpli,
Trine M. Reine,
Beate Hegge,
Stephanie Rose Nielsen,
Meng Chen
m.fl.:
Serglycin is Involved in TGF-β induced epithelial-mesenchymal transition and is highly expressed by immune cells in breast cancer tissue
Elisa Fiorito,
Patrycja Maria Szybowska,
Ellen Margrethe Haugsten,
Michal Janusz Kostas,
Geir Frode Øy,
Antoni Wiedlocha
m.fl.:
Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
Anne Hansen Ree,
Gunhild Mari Mælandsmo,
Kjersti Flatmark,
Hege Elisabeth Giercksky Russnes,
Monica Gomez Casteneda,
Eline Aas
:
Cost-effectiveness of molecularly matched off-label therapies for end-stage cancer – the MetAction precision medicine study
Caroline Elisabeth Nunes-Xavier,
Maite Emaldi,
Ingrid Jenny Guldvik,
Håkon Ramberg,
Kristin Austlid Tasken,
Gunhild Mari Mælandsmo
m.fl.:
Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer
Sunniva Bjørklund,
Miriam Ragle Aure,
Jari Häkkinen,
Johan Vallon-Christersson,
Surendra Kumar,
Katrine Bull Evensen
m.fl.:
Subtype and cell type specific expression of lncRNAs provide insight into breast cancer
Lisa Svartdal Normann,
Mads Haugland Haugen,
Miriam Ragle Aure,
Vessela N. Kristensen,
Gunhild Mari Mælandsmo,
Kristine Kleivi Sahlberg
:
miR-101-5p Acts as a Tumor Suppressor in HER2-Positive Breast Cancer Cells and Improves Targeted Therapy
Margherita Ambrosini,
Marzia Del Re,
Paolo Manca,
Andrew Hendifar,
Alexander Drilon,
Guilherme Harada
m.fl.:
ALK Inhibitors in Patients with ALK Fusion-Positive GI Cancers: An International Data Set and a Molecular Case Series
Sigurdur Karvelsson,
Arnar Sigurdsson,
Kotryna Seip,
Maria Tunset Grinde,
Qiong Wang,
Freyr Johanssson
m.fl.:
EMT-derived alterations in glutamine metabolism sensitize mesenchymal breast cells to mTOR inhibition
Vegar Johansen Dagenborg,
Serena Marshall,
Krzysztof Grzyb,
Åsmund Avdem Fretland,
Marius Lund-Iversen,
Gunhild Mari Mælandsmo
m.fl.:
Low Concordance Between T-Cell Densities in Matched Primary Tumors and Liver Metastases in Microsatellite Stable Colorectal Cancer
Henrik Aasrum Svendsen,
Torstein Ragnar Meling,
Vigdis Nygaard,
Stein Waagene,
Hege Elisabeth Giercksky Russnes,
Siri Juell
m.fl.:
Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin
Mateusz Adam Krzyscik,
Malgorzata Zakrzewska,
Vigdis Sørensen,
Geir Frode Øy,
Skjalg Bruheim,
Ellen Margrethe Haugsten
m.fl.:
Fibroblast growth factor 2 conjugated with monomethyl auristatin E inhibits tumor growth in a mouse model
Lisa Gregusson Svartdal Normann,
Miriam Ragle Aure,
Suvi-Katri Leivonen,
Mads Haugland Haugen,
Vesa Hongisto,
Vessela N. Kristensen
m.fl.:
MicroRNA in combination with HER2-targeting drugs reduces breast cancer cell viability in vitro
Tripti Tamhane,
Robin W. Njenga,
Roberta E. Burden,
Heiko Büth,
Gunhild Mari Mælandsmo,
Mads Haugland Haugen
m.fl.:
Trafficking of full-length and N-terminally truncated cathepsin B in human colorectal carcinoma cells
Applied Sciences 2021 DOI
Inga Hansine Rye,
Kanutte Huse,
Sarah Elisabet Josefsson,
Wanja Kildal,
Håvard Emil Greger Danielsen,
Ellen Schlichting
m.fl.:
Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression
Caroline Elisabeth Nunes-Xavier,
Wanja Kildal,
Andreas Kleppe,
Håvard Emil Greger Danielsen,
Håkon Wæhre,
Roberto Llarena
m.fl.:
Immune checkpoint B7-H3 protein expression is associated with poor outcome and androgen receptor status in prostate cancer
Mads Haugland Haugen,
Ole Christian Lingjærde,
Ingrid Hedenfalk,
Øystein Garred,
Elin Borgen,
Niklas Loman
m.fl.:
Protein signature predicts response to neoadjuvant treatment with chemotherapy and bevacizumab in HER2-negative breast cancers
Xing Yi Woo,
Jessica Giordano,
Anuj Srivastava,
Zi-Ming Zhao,
Michael W. Lloyd,
Roebi de Bruijn
m.fl.:
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
Nature Genetics 2021 DOI
Remya Valsalakumari,
Sunil Kumar Yadava,
Marzena Szwed,
Abhilash D. Pandya,
Gunhild Mari Mælandsmo,
Maria Lyngaas Torgersen
m.fl.:
Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells.
Anna Barkovskaya,
Craig Goodwin,
Kotryna Seip,
Bylgja Hilmarsdòttir,
Solveig Pettersen,
Clint Stalnecker
m.fl.:
Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen
Abhilash D. Pandya,
Tore Geir Iversen,
Siver Andreas Moestue,
Maria Tunset Grinde,
Ýrr Asbjørg Mørch,
Sofie Snipstad
m.fl.:
Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
Sigurdur Karvelsson,
Qiong Wang,
Bylgja Hilmarsdòttir,
Arnar Sigurdsson,
Siver Andreas Moestue,
Gunhild Mari Mælandsmo
m.fl.:
Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer
Karianne Giller Fleten,
Jacobus Johannes Eksteen,
Brynjar Mauseth,
Ketil André Camilio,
Terje Vasskog,
Baldur Sveinbjørnsson
m.fl.:
Oncolytic peptides DTT-205 and DTT-304 induce complete regression and protective immune response in experimental murine colorectal cancer
Vegar Johansen Dagenborg,
Serena Elizabeth Marshall,
Krzysztof Grzyb,
Åsmund Avdem Fretland,
Marius Lund-Iversen,
Gunhild Mari Mælandsmo
m.fl.:
Low concordance between T-cell densities in matched primary tumors and liver metastases in microsatellite stable colorectal cancer
Frontiers in Oncology 2020
Maria Lyngaas Torgersen,
Peter J. Judge,
Juan F. Bada Juarez,
Abhilash D. Pandya,
Markus Fusser,
Charlie W. Davies
m.fl.:
Physicochemical characterization, toxicity and in vivo biodistribution studies of a discoidal, lipid-based drug delivery vehicle: Lipodisq nanoparticles containing doxorubicin
Anne Hansen Ree,
Vigdis Nygaard,
Kjetil Boye Pedersen,
Daniel Heinrich,
Svein Dueland,
Inger Riise Bergheim
m.fl.:
Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer?the MetAction study
Ann Rita Halvorsen,
Mads Haugland Haugen,
Åsa Kristina Øjlert,
Marius Lund-Iversen,
Lars Hilmar Jørgensen,
Steinar Solberg
m.fl.:
Protein kinase C isozymes associated with relapse free survival in non-small cell lung cancer patients
Sophie Sarah Steinhaeuser,
Erika Morera,
Zuzana Budkova,
Alexander Schepsky,
Qiong Wang,
Ottar Rolfsson
m.fl.:
ECM1 secreted by HER2-overexpressing breast cancer cells promotes formation of a vascular niche accelerating cancer cell migration and invasion
Laboratory Investigation 2020 DOI
Pierre Dillard,
Hakan Köksal,
Solrun Melkorka Maggadottir,
Anna Katharina Winge-Main,
Sylvie Mireille Pollmann,
Mathilde Ménard
m.fl.:
Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
Molecular Therapy 2020 DOI
Abhilash D. Pandya,
Anders Øverbye,
Priyanka Saharia,
Vivek S. Gaware,
Håkon Høgset,
Már Masson
m.fl.:
Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
Karine Flem-Karlsen,
Marta Sølvi Nyakas,
Inger Nina Farstad,
Erin McFadden,
Patrik Vernhoff,
Kari Dolven Jacobsen
m.fl.:
Soluble AXL as a marker of disease progression and survival in melanoma
Erik Knutsen,
Seyed Mohammad Lellahi,
Miriam Ragle Aure,
Silje Nord,
Silje Fismen,
Kenneth Bowitz Larsen
m.fl.:
The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers
Jingjing Liu,
Wendy J. C. Prager van der Smissen,
Margriet J. Collee,
Manjeet K. Bolla,
Qin Wang,
Vessela N. Kristensen
m.fl.:
Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk
Abhilash D. Pandya,
Eliézer Jäger,
Shahla Bagheri Fam,
Anita Höcherl,
Alessandro Jäger,
Vladimir Sincari
m.fl.:
Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy
Karine Flem-Karlsen,
Christina Tekle,
Tove Ragnhild Øyjord,
Vivi Ann Flørenes,
Gunhild Mari Mælandsmo,
Øystein Fodstad
m.fl.:
p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance
Ketil Andre Camilio,
Mengyu Wang,
Brynjar Mauseth,
Stein Waagene,
Gunnar Kvalheim,
Øystein Rekdal
m.fl.:
Combining the oncolytic peptide LTX-315 with doxorubicin demonstrates therapeutic potential in a triple-negative breast cancer model
Anne Hansen Ree,
Vigdis Nygaard,
Hege Elisabeth Giercksky Russnes,
Daniel Heinrich,
Vegard Nygaard,
Christin Johansen
m.fl.:
Responsiveness to PD-1 Blockade in End-Stage Colon Cancer with Gene Locus 9p24.1 Copy-Number Gain
Maria Tunset Grinde,
Bylgja Hilmarsdòttir,
Hanna Maja Tunset,
Ida Marie Henriksen,
Jana Kim,
Mads Haugland Haugen
m.fl.:
Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer
Caroline Elisabeth Nunes-Xavier,
Maite Emaldi,
Janire Mingo,
Tove Ragnhild Øyjord,
Gunhild Mari Mælandsmo,
Øystein Fodstad
m.fl.:
Author Correction: The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma (Scientific Reports, (2023), 13, 1, (7339), 10.1038/s41598-023-34087-x)
Scientific Reports 2023 DOI
Markus Fusser,
Anders Øverbye,
Abhilash D. Pandya,
Ýrr Asbjørg Mørch,
Sven Even F. Borgos,
Wanja Kildal
m.fl.:
Corrigendum to “Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft”, [Journal of Control Release, 293 (2019) 183–192, (Journal of Control Release, (2019) 293(183-192) (S0168365918306928), (10.1016/j.jconrel.2018.11.029))
Journal of Controlled Release 2022 DOI
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