Engelsk personkortSeredkina, Natalya
Postdoktor
Medisinsk biologi
Funksjon
Postdoktor
Telefon
776 20937
Epost
Kontor/besøksadresse
Medisin og Helsefag
MH L8.229
Stillingsbeskrivelse
Forsker i Molecular Pathology Research group
Forskningsinteresser
Immunology
Systemic lupus erythematosus
Lupus nephritis
Andre publikasjoner
1. Nedashkovsky E.V., M.Y. Kirov, E.M. Egorina, M.A. Sovershaev, N.E. Seredkina and O.V. Evgenov. SAPS II: our experience of use in septic shock [In Russian]. Intensive Care Herald, 1999; 2: 3-7
CV
Utdanning
1999 M.D. Arkhangelsk State Medical Academy, Arkhangelsk, Russia
2011 Ph.D. in Molecular and Structural Biology University of Tromsø, Tromsø, Norway
Yrkespraksis
1999-2000 Internship Department of Internal Medicine, Northern State Medical University, Arkhangelsk, Russia
2000-2002 Clinical fellowship Department of Internal Medicine, Northern State Medical University, Arkhangelsk, Russia
2000-2006 Physician Department of Internal Medicine, Region Clinical Hospital, Arkhangelsk, Russia
2001-2006 Cardiologist Department of Cardiology, Region Clinical Hospital, Arkhangelsk, Russia
Arbeider i CRIStin
- Fismen, Silje; Thiyagarajan, Dhivya; Seredkina, Natalya; Nielsen, Henrik; Jacobsen, Søren; Elung-Jensen, Thomas; Kamper, Anne-Lise; Johansen, Steinar; Mortensen, Elin Synnøve; Rekvig, Ole Petter. Impact of the Tumor Necrosis Factor Receptor-Associated Protein 1 (Trap1) on Renal DNaseI Shutdown and on Progression of Murine and Human Lupus Nephritis. American Journal of Pathology 2013; Volum 182 (3). ISSN 0002-9440.s 688 - 700.s doi: 10.1016/j.ajpath.2012.11.013.
- Thiyagarajan, Dhivya; Fismen, Silje; Seredkina, Natalya; Jacobsen, Søren; Elung-Jensen, Thomas; Kamper, Anne-Lise; Fenton, Christopher Graham; Rekvig, Ole Petter; Mortensen, Elin Synnøve. Silencing of Renal DNaseI in Murine Lupus Nephritis Imposes Exposure of Large Chromatin Fragments and Activation of Toll Like Receptors and the Clec4e. PLoS ONE 2012; Volum 7 (3). ISSN 1932-6203.s doi: 10.1371/journal.pone.0034080.
- Egorina, Elena; Sovershaev, Mikhail; Bogdanov, Vladimir; Sovershaev, TA; Fallon, John T.; Seredkina, Natalya; Østerud, Bjarne; Hansen, John-Bjarne. Low thrombogenicity of calcified atherosclerotic plaques is associated with bone morphogenetic protein-2-dependent inhibition of tissue factor expression. Blood Coagulation and Fibrinolysis 2011; Volum 22 (8). ISSN 0957-5235.s 642 - 650.s doi: 10.1097/MBC.0b013e32834a49fd.
- Seredkina, Natalya; Rekvig, Ole Petter. Acquired loss of renal nuclease activity is restricted to DNaseI and is an organ-selective feature of murine lupus nephritis. American Journal of Pathology 2011. ISSN 0002-9440.s doi: 10.1016/j.ajpath.2011.05.011.
- Sovershaev, Mikhail; Egorina, Elena; Bogdanov, Vladimir; Seredkina, Natalya; Fallon, JT; Valkov, Andrey Yurjevich; Østerud, Bjarne; Hansen, John-Bjarne. Bone morphogenetic protein-7 increases thrombogenicity of lipid-rich atherosclerotic plaques via activation of tissue factor. Thrombosis Research 2010; Volum 126 (4). ISSN 0049-3848.s 306 - 310.s doi: 10.1016/j.thromres.2010.06.026.
- Fenton, Kristin Andreassen; Fismen, Silje; Hedberg, Annica; Seredkina, Natalya; Fenton, Christopher Graham; Mortensen, Elin; Rekvik, Ole Petter. Anti-dsDNA Antibodies Promote Initiation, and Acquired Loss of Renal Dnase1 Promotes Progression of Lupus Nephritis in Autoimmune (NZBxNZW)F1 mice. PLoS ONE 2009; Volum 4 (12). ISSN 1932-6203.s doi: 10.1371/journal.pone.0008474.
- Seredkina, Natalya; Zykova, Svetlana; Rekvik, Ole Petter. Progression of Murine Lupus Nephritis Is Linked to Acquired Renal Dnase1 Deficiency and Not to Up-Regulated Apoptosis. American Journal of Pathology 2009; Volum 175 (1). ISSN 0002-9440.s 97 - 106.s doi: 10.2353/ajpath.2009.080943.
- Zykova, Svetlana; Seredkina, Natalya; Benjaminsen, Jørgen; Rekvik, Ole Petter. Reduced fragmentation of apoptotic chromatin is associated with nephritis in lupus-prone (NZB x NZW)F-1 mice. Arthritis and Rheumatism 2008; Volum 58. ISSN 0004-3591.s 813 - 825.s doi: 10.1002/art.23276.
- Zykova, Svetlana; Seredkina, Natalya; Rekvik, Ole Petter. Glomerular targets for autoantibodies in lupus nephritis - An apoptotic origin. Annals of the New York Academy of Sciences 2007; Volum 1108. ISSN 0077-8923.s 1 - 10.s doi: 10.1196/annals.1422.001.
- Seredkina, Natalya. Lupus nephritis: the role of DNase I in the progression of the disease. 2011 ISBN 978-82-7589-310-7.
- Seredkina, Natalya; Rekvig, Ole Petter. Acquired loss of renal Dnase1 is an organ specific feature for severe lupus nephritis. PhD school in Molecular and Structural Biology Open Day 2010-10-15 - 2010-10-15 2010.
- Seredkina, Natalya. Reduced renal Dnase1 expression and activity is unique to murine lupus nephritis. 7th International Congress on Autoimmunity 2010-05-05 - 2010-05-09 2010.
- Seredkina, Natalya; Zykova, Svetlana; Rekvig, Ole Petter. Analysis of apoptotic activity in lupus nephritis. PhD school in Molecular and Structural Biology Open Day 2007-09-21 - 2007-09-21 2007.
