Universitetet i Tromsø - Startsida Universitetet i Tromsø - Startsida
 
Medisinsk biologi


Gutteberg, Tore Jarl

Professor II
Medisinsk biologi

Funksjon
Professor II

Telefon
776 27042

Epost

Kontor/besøksadresse
UNN
UNN
Tore Jarl Guttenberg.jpg (Bredde: 180px)

Mobil privat
+4791316423

Alternativ Kontaktinfo

Verv

Medlem av
Tromsø mineskadesenter, Helse Nord TB (og HIV) Malawi, Resistens mot antivirale midler i Norge (RAVN),nestleder interimstyret NUFU NOMA (SIU)


Forskerprofil i Cristin

Forskningsinteresser

Antiviral forskning:polyomavirus,HIV,HCV,HSV,CMV med vekt nå på HCV terapi og mekanismer på polyomavirus


Forskningsprosjekter

Hepatitt Nord Norge  pågått siden 1990 nå med vekt på “direct acting antivirals” (DAA) og vertsrespons, dagli
Antiviral mekanismeforståelse i “Antiviral Research Group”,daglig leder Dr.Christine Rinaldo


CV

Utdanning:
Educational Council for Foreign Medical Graduates (151-989-1) 19.03.1971(Dublin/USA)
Cand.med. RCSI, Dublin 1971
Autorisert i UK/Irland & Norge 1973
Barnelege 1978
Medisnsk (klinisk) mikrobiolog 1990
Dr. med.(Ph D) 1991

Yrkespraksis: 
Barnelege: Tromsø, Hamilton (Ontario), Gøteborg, Rikshospitalet (Oslo),overlegeerfaring Tromsø og Oslo
Klinisk mikrobiolog Tromsø med opphold  UCSD,Ca (1977-8), overlege fra 1990
Amanuensis i barnesykdommer 1 år (1978-9), første amanuensis /professor II fra 1995(?)

Fullstendig CV


Interesser

 
Internasjonal politikk, global helse, bildende kunst, natur,jazz og møte med andre kulturer



Arbeider i CRIStin

  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve; Skjeldestad, Finn Egil. HPV mRNA testing in triage of women with ASC-US cytology may reduce the time for CIN2+ diagnosis compared with repeat cytology. Current pharmaceutical design 2013; Volum 19 (8). ISSN 1381-6128.s 1401 - 1405.s doi: 10.2174/138161213804805487.
  • Viet, Le; Nguyen, Thi Ngoc Lan; Ty, Phung Xuan; Bjørkvoll, Bjørn; Hoel, Hedda B; Gutteberg, Tore Jarl; Husebekk, Anne; Larsen, Stig; Skjerve, Eystein; Husum, Hans. Prevalence of hepatitis B & hepatitis C virus infections in potential blood donors in rural Vietnam. (fulltekst) Indian Journal of Medical Research (IJMR) 2012; Volum 136 (1). ISSN 0971-5916.s 74 - 81.
  • Sørbye, Sveinung Wergeland; Arbyn, Marc; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve. HPV E6/E7 mRNA Testing Is More Specific than Cytology in Post-Colposcopy Follow-Up of Women with Negative Cervical Biopsy. PLoS ONE 2011; Volum 6 (10). ISSN 1932-6203.s doi: 10.1371/journal.pone.0026022.
  • Sharma, Biswa Nath; Li, Ruomei; Bernhoff, Eva; Gutteberg, Tore Jarl; Rinaldo, Christine H. Fluoroquinolones inhibit human polyomavirus BK (BKV) replication in primary human kidney cells. Antiviral Research 2011; Volum 92 (1). ISSN 0166-3542.s 115 - 123.s doi: 10.1016/j.antiviral.2011.07.012.
  • Florholmen, Jon; Kristiansen, Magnhild Gangsøy; Steigen, Sonja Eriksson; Sørbye, Sveinung Wergeland; Paulssen, Eyvind Jakob; Kvamme, Jan-Magnus; Zbigniew, Konopski; Gutteberg, Tore Jarl; Goll, Rasmus. A rapid chemokine response of macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and the regulated on activation, normal T expressed and secreted chemokine is associated with a sustained virological response in the treatment of chronic hepatitis C. Clinical Microbiology and Infection 2011; Volum 17 (2). ISSN 1198-743X.s 204 - 209.s doi: 10.1111/j.1469-0691.2010.03206.x.
  • Sørbye, Sveinung Wergeland; Arbyn, Marc; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin. Triage of Women with Low-Grade Cervical Lesions - HPV mRNA Testing versus Repeat Cytology. PLoS ONE 2011; Volum 6 (8). ISSN 1932-6203.s doi: 10.1371/journal.pone.0024083.
  • Kristiansen, Magnhild Gangsøy; Løchen, Maja-Lisa; Gutteberg, tore jarl; Mortensen, Liisa; Eriksen, Bjørn Odvar; Florholmen, Jon. Total and cause-specific mortality rates in a prospective study of community-acquired hepatitis C virus infection in northern Norway. Journal of Viral Hepatitis 2011; Volum 18 (4). ISSN 1352-0504.s 237 - 244.s doi: 10.1111/j.1365-2893.2010.01290.x.
  • Bernhoff, Eva; Tylden, Garth Daryl; Kjerpeseth, Lars Jøran; Gutteberg, Tore Jarl; Hirsch, Hans H.; Rinaldo, Christine H. Leflunomide Inhibition of BK Virus Replication in Renal Tubular Epithelial Cells. Journal of Virology 2010; Volum 84 (4). ISSN 0022-538X.s 2150 - 2156.s doi: 10.1128/JVI.01737-09.
  • Kristiansen, Magnhild Gangsøy; Gutteberg, Tore Jarl; Mortensen, Liisa; Berg, Leif Kyrre; Goll, Rasmus; Florholmen, Jon. Clinical outcomes in a prospective study of community-acquired hepatitis C virus infection in Northern Norway. Scandinavian Journal of Gastroenterology 2010; Volum 45 (6). ISSN 0036-5521.s 746 - 751.s doi: 10.3109/00365521003690699.
  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin. Triage of Women with Minor Cervical Lesions: Data Suggesting a "Test and Treat" Approach for HPV E6/E7 mRNA Testing. PLoS ONE 2010; Volum 5 (9). ISSN 1932-6203.s doi: 10.1371/journal.pone.0012724.
  • Bjørkvoll, Bjørn; Le, Viet; Ol, Ha Sam; Nguyen, Thi Ngoc Lan; Sothy, Sin; Hoel, Hedda B; Gutteberg, Tore Jarl; Husebekk, Anne; Larsen, Stig; Husum, Hans. Screening test accuracy among potential blood donors of HBsAG, anti-HBc and anti-HCV to detect Hepatitis B and C virus infection in rural Cambodia and Vietnam. Southeast Asian journal of tropical medicine and public health 2010; Volum 41 (5). ISSN 0125-1562.s 1127 - 1135.
  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin. HPV mRNA test in women with minor cervical lesions: Experience of the University Hospital of North Norway. Journal of Virological Methods 2010; Volum 169 (1). ISSN 0166-0934.s 219 - 222.s doi: 10.1016/j.jviromet.2010.07.011.
  • Ol, HS; Bjoerkvoll, B; Sothy, S; Van Heng, Y; Hoel, H; Husebekk, Anne; Gutteberg, tore jarl; Larsen, S; Husum, Hans. PREVALENCE OF HEPATITIS B AND HEPATITIS C VIRUS INFECTIONS IN POTENTIAL BLOOD DONORS IN RURAL CAMBODIA. Southeast Asian journal of tropical medicine and public health 2009; Volum 40 (5). ISSN 0125-1562.s 963 - 971.
  • Hvidsten, Dag; Halvorsen, Dag; Berdal, Bjørn Peter; Gutteberg, Tore Jarl. Chlamydophila pneumoniae diagnostics: importance of methodology in relation to timing of sampling. Clinical Microbiology and Infection 2009; Volum 15 (1). ISSN 1198-743X.s 42 - 49.s doi: 10.1111/j.1469-0691.2008.02075.x.
  • Kristiansen, Magnhild Gangsøy; Eriksen, Bjørn Odvar; Maltau, Jan Martin; Holdo, B; Gutteberg, Tore Jarl; Mortensen, Liisa; Løchen, Maja-Lisa; Florholmen, Jon. Prevalences of Viremic Hepatitis C and Viremic Hepatitis B in Pregnant Women in Northern Norway. Hepato-Gastroenterology 2009; Volum 56 (93). ISSN 0172-6390.s 1141 - 1145.
  • Kristiansen, Magnhild Gangsøy; Løchen, Maja-Lisa; Gutteberg, Tore Jarl; Falk, Edvard S; Mortensen, Liisa; Florholmen, Jon; Eriksen, Bjørn Odvar. Hepatitis C virus infection was not found in patients with sporadic porphyria cutanea tarda, membranoproliferative glomerulonephritis or membranous glomerulonephritis in Northern Norway. Scandinavian Journal of Gastroenterology 2009; Volum 44 (7). ISSN 0036-5521.s 894 - 896.s doi: 10.1080/00365520902803523.
  • Lindsetmo, Rolv-Ole; Johnsen, Roar; Eide, Tor j; Gutteberg, tore jarl; Husum, Hanne Haukland; Revhaug, Arthur. Accuracy of Helicobacter pylori serology in two peptic ulcer populations and in healthy controls. World Journal of Gastroenterology 2008; Volum 14. ISSN 1007-9327.s 5039 - 5045.s doi: 10.3748/wjg.14.5039.
  • Bernhoff, Eva; Gutteberg, tore jarl; Sandvik, Kjersti; Hirsch, Hans H.; Rinaldo, christine h. Cidofovir inhibits polyomavirus BK replication in human renal tubular cells downstream of viral early gene expression. American Journal of Transplantation 2008; Volum 8. ISSN 1600-6135.s 1413 - 1422.s doi: 10.1111/j.1600-6143.2008.02269.x.
  • Halvorsen, Dag Seeger; Karlsen, Joachim; Notø, Ann-Trude With; Mathiesen, Ellisiv B.; Njølstad, Inger; Gutteberg, tore jarl; Vorland, lars; Hansen, John-Bjarne. No detectable Chlamydia pneumoniae and cytomegalovirus DNA in leukocytes in subjects with echolucent and echogenic carotid artery plaques. International Journal of Cardiology 2007; Volum 117. ISSN 0167-5273.s doi: 10.1016/j.ijcard.2006.05.025.
  • Jenssen, Håvard; Gutteberg, tore jarl; Rekdal, Øystein; Lejon, Tore Sigvard. Prediction of activity, synthesis and biological testing of anti-HSV active peptides. Chemical Biology and Drug Design 2006; Volum 68. ISSN 1747-0277.s 58 - 66.
  • Jenssen, Håvard; Gutteberg, tore jarl; Lejon, Tore Sigvard. MODELLING THE ANTI-HSV ACTIVITY OF SMALL, CATIONIC PEPTIDES USING AMINO ACID DESCRIPTORS. Journal of Peptide Research 2006; Volum 66. ISSN 1397-002X.s 48 - 56.
  • Jenssen, Håvard; Gutteberg, Tore Jarl; Lejon, Tore Sigvard. Modelling of anti-HSV activity of lactoferricin analogues using amino acid descriptors. Journal of Peptide Science 2005; Volum 11 (2). ISSN 1075-2617.s 97 - 103.
  • Hunter, HN; Demcoe, AR; Jenssen, Håvard; Gutteberg, Tore Jarl; Vogel, HJ. Human lactoferricin is partially folded in aqueous solution and is better stabilized in a membrane mimetic solvent. Antimicrobial Agents and Chemotherapy 2005; Volum 49 (8). ISSN 0066-4804.s 3387 - 3395.
  • Andersen, Jeanette Hammer; Jenssen, Håvard; Sandvik, K; Gutteberg, Tore Jarl. The anti-HSV activity of lactoferrin and lactoferricin is dependent on the presence of heparan sulphate at the cell surface.. Journal of Medical Virology 2004; Volum 74. ISSN 0146-6615.s 262 - 271.
  • Husebekk, Anne; Skaug, K; Kolstad, A; Dahl, Inger Marie; Gutteberg, Tore Jarl; Skogen, Bjørn Ragnar. Hepatitis B virus-infected peripheral blood progenitor cell harvests in liquid nitrogen freezer containing non-infectious products. Transfusion 2004; Volum 44 (6). ISSN 0041-1132.s 942 - 3.
  • Jenssen, Håvard; Andersen, Jeanette Hammer; Uhlin-Hansen, Lars; Gutteberg, Tore Jarl; Rekdal, Øystein. Anti-HSV activity of lactoferricin analogues is only partly related to their affinity for heparan sulfate. Antiviral Research 2004; Volum 61. ISSN 0166-3542.s 101 - 109.
  • Vorland, Lars; Ulvatne, H.; Andersen, Johan Henr; Haukland, Hanne; Rekdal, Øystein; Svendsen, John Sigurd; Gutteberg, Tore Jarl. Antibacterial effects of lactoferricin B.. Scandinavian Journal of Infectious Diseases 1999; Volum 31. ISSN 0036-5548.s 179 - .
  • Vorland, Lars; Osbakk, S. A.; Perstølen, T.; Ulvatne, H.; Rekdal, Øystein; Svendsen, John Sigurd; Gutteberg, Tore Jarl. Interference of the Anti-microbial peptide lactoferricin B with the action of various antibiotics against Escherichia coli and Staphylococcus aureus.. Scandinavian Journal of Infectious Diseases 1999; Volum 31. ISSN 0036-5548.s 173 - .
  • Vorland, Lars; Ulvatne, H.; Andersen, Johan Henr; Haukland, Hanne; Rekdal, Øystein; Svendsen, John Sigurd; Gutteberg, Tore Jarl. Lactoferricin of bovine origin is more active than lactoferricins of human, murine and caprine origin.. Scandinavian Journal of Infectious Diseases 1998. ISSN 0036-5548.
  • Sørbye, Sveinung Wergeland; Gutteberg, Tore Jarl. Frykter helsepersonell influensasmitter pasienter. (fulltekst) 2013.
  • Sørbye, Sveinung Wergeland; Fismen, Silje; Mortensen, Elin Synnøve; Gutteberg, Tore Jarl; Skjeldestad, Finn Egil. Post-colposcopy follow-up of women with negative cervical biopsy - a prospecitve study. Eurogin 2012 2012-07-08 - 2012-07-11 2012.
  • Sørbye, Sveinung Wergeland; Fismen, Silje; Mortensen, Elin Synnøve; Gutteberg, Tore Jarl; Skjeldestad, Finn Egil. HPV mRNA and cytology cotesting in primary cervical caner screening by age. IPV 2012 2012-11-30 - 2012-12-06 2012.
  • Sørbye, Sveinung Wergeland; Fismen, Silje; Mortensen, Elin Synnøve; Gutteberg, Tore Jarl. HPV-test i forebygging av livmorhalskreft. Tidsskrift for Den norske legeforening 2012; Volum 132 (4). ISSN 0029-2001.s 396 - 397.s doi: 10.4045/tidsskr.11.0976.
  • Rinaldo, Christine H; Li, Ruomei; Sharma, Biswa Nath; Linder, Stig; Gutteberg, Tore Jarl; Hirsch, Hans H.. Polyomavirus BK (BKV) Replication in Human Urothelial Cells Role in Polyomavirus-Associated Nephropathy and Hemorrhagic Cystitis. American Journal of Transplantation 2012; Volum 12. ISSN 1600-6135.s 348 - 348.
  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve. Redegjør for HPV-resultater. (fulltekst) Dagens medisin 2011. ISSN 1501-4290.
  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve; Skjeldestad, Finn Egil. HPV mRNA testing - longterm follow-up. EUROGIN 2011-05-08 - 2011-05-11 2011.
  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve; Skjeldestad, Finn Egil. HPV mRNA test in primry screening of women 20-34 years. The 27th international Papillomavirus conference 2011-09-17 - 2011-09-22 2011.
  • Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve. HPV-testing og livmorhalskreft. Tidsskrift for Den norske legeforening 2011; Volum 3 (131). ISSN 0029-2001.s 333 - 333.s doi: 10.4045/tidsskr.10.1426.
  • Bjørkvoll, Bjørn; Viet, Le; Ol, Ha Sam; Lan, Nguyen Thi Ngoc; Husebekk, Anne; Hoel, Hedda B; Larsen, Stig; Sothy, S; Gutteberg, tore jarl; Husum, Hans. Screening test accuracy among potential blood donors of HBSAg, Anti-HBC and Anti-HCV to detect hepatitis B and C virus infection in rural Cambodia and Vietnam. Southeast Asian journal of tropical medicine and public health 2010; Volum 41 (5). ISSN 0125-1562.s 1127 - 1135.
  • Sørbye, Sveinung Wergeland; Gutteberg, Tore Jarl; Vintermyr, Olav Karsten. Ny generasjon HPV-tester på vent. (fulltekst) 2010.
  • Lie, Kathrine; Jonassen, Christine M.; Vogt, Christina; Vintermyr, Olav Karsten; Hanssen, Tor-Arne; Gutteberg, tore jarl. Fjerne HPV-takst i sekundærscreening?. Dagens medisin 2010; Volum 06 (22). ISSN 1501-4290.
  • Bernhoff, Eva; Tylden, Garth Daryl; Kjerpeseth, LJ; Gutteberg, tore jarl; Hirsch, HH; Rinaldo, christine h. Leflunomide inhibits BK virus replication but simultaneously compromises renal tubular epithelial cell proliferation. Journal of Clinical Virology 2009; Volum 46. ISSN 1386-6532.s S56 - S56.
  • Gutteberg, tore jarl; Rinaldo, christine h. Lactoferrin confidential: ancient actor starring in new role?. Transplant Infectious Disease 2008; Volum 10. ISSN 1398-2273.s 77 - 79.
  • Rinaldo, christine h; Bernhoff, E; Tylden, G; Sandvik, K; Hirsch, HH; Gutteberg, tore jarl. Time-dependent effect of cidofovir and leflunomide on polyomavirus BK replication and kidney cell viability.. American Journal of Transplantation 2008; Volum 8. ISSN 1600-6135.s 462 - 463.
  • Kristiansen, Magnhild Gangsøy; Løchen, Maja-Lisa; Maltau, Jan Martin; Holdø, B.; Gutteberg, tore jarl; Mortensen, L.; Eriksen, Bjørn Odvar; Florholmen, Jon. Prevalence of hepatitis C and B in pregnant women in the Northern Norway health region. 13th United European Gastroenterology Week 2005-10-15 - 2005-10-19 2005.
  • Jensen, Håvard; Gutteberg, Tore Jarl; Rekdal, Øystein; Lejon, Tore Sigvard. Prediction of activity, synthesis and biological testing of anti-HSV active peptides.. Organisk Kjemisk Vintermøte 2005 2005-01-13 - 2005-01-16 2005.
  • Jensen, Håvard; Gutteberg, Tore Jarl; Lejon, Tore Sigvard. Modelling of anti-HSV activity of lactoferricin analogues using amino acid descriptors.. Euro QSAR 2004 2004-09-05 - 2004-09-10 2004.
   Se alle arbeider i CRIStin



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